Neonatal antiphospholipid syndrome

Detalhes bibliográficos
Autor(a) principal: Rolim, A. M. Soares
Data de Publicação: 2006
Outros Autores: Castro, M., Santiago, Mittermayer Barreto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/12943
Resumo: Texto completo: acesso restrito. p.301–303
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spelling Rolim, A. M. SoaresCastro, M.Santiago, Mittermayer BarretoRolim, A. M. SoaresCastro, M.Santiago, Mittermayer Barreto2013-09-16T17:18:30Z20060961-2033http://www.repositorio.ufba.br/ri/handle/ri/12943v.15 n. 5Texto completo: acesso restrito. p.301–303Antiphospholipid syndrome (APS) is a clinical entity characterized by arterial and venous thrombosis, adverse obstetric outcome and the presence of antibodies against phospholipids in serum or plasma. The objective of the present study is to describe a rare case of APS that occurred in a neonate born from a patient previously diagnosed as primary APS. A male, preterm born twin infant, whose mother had been diagnosed as primary APS, developed thrombocytopenia, livedo reticularis, pericardial effusion and thrombosis of the left subclavian and external jugular veins concomitantly with severe respiratory tract infection soon after his delivery, that culminated with his death two months after the birth, in spite of the large spectrum antibiotic therapy and all supportive measures. Laboratory findings included high titers of IgM anticardiolipin antibodies and moderate titers of IgG isotype and negative antinuclear antibody, configuring a case of neonatal APS. Neonatal APS is a rare clinical condition, with only a few cases described in the literature. Its occurrence may depend on the passage of antibodies through the placenta or, as it seems to have occurred in the present case, by the production of de novo antibodies by the fetus. The present case illustrates the necessity of a higher surveillance of the neonates born from mothers with primary APS or systemic lupus erythematosus (SLE) for the eventual development of such complication.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-08-22T12:32:01Z No. of bitstreams: 1 301.full.pdf: 129500 bytes, checksum: df7c42b8aeb6d9351f796519e43274bb (MD5)Approved for entry into archive by Flávia Ferreira(flaviaccf@yahoo.com.br) on 2013-09-16T17:18:30Z (GMT) No. of bitstreams: 1 301.full.pdf: 129500 bytes, checksum: df7c42b8aeb6d9351f796519e43274bb (MD5)Made available in DSpace on 2013-09-16T17:18:30Z (GMT). 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dc.title.pt_BR.fl_str_mv Neonatal antiphospholipid syndrome
dc.title.alternative.pt_BR.fl_str_mv Lupus
title Neonatal antiphospholipid syndrome
spellingShingle Neonatal antiphospholipid syndrome
Rolim, A. M. Soares
Antiphospholipid syndrome;
Systemic lupus erythematosus;
Neonatal
title_short Neonatal antiphospholipid syndrome
title_full Neonatal antiphospholipid syndrome
title_fullStr Neonatal antiphospholipid syndrome
title_full_unstemmed Neonatal antiphospholipid syndrome
title_sort Neonatal antiphospholipid syndrome
author Rolim, A. M. Soares
author_facet Rolim, A. M. Soares
Castro, M.
Santiago, Mittermayer Barreto
author_role author
author2 Castro, M.
Santiago, Mittermayer Barreto
author2_role author
author
dc.contributor.author.fl_str_mv Rolim, A. M. Soares
Castro, M.
Santiago, Mittermayer Barreto
Rolim, A. M. Soares
Castro, M.
Santiago, Mittermayer Barreto
dc.subject.por.fl_str_mv Antiphospholipid syndrome;
Systemic lupus erythematosus;
Neonatal
topic Antiphospholipid syndrome;
Systemic lupus erythematosus;
Neonatal
description Texto completo: acesso restrito. p.301–303
publishDate 2006
dc.date.issued.fl_str_mv 2006
dc.date.accessioned.fl_str_mv 2013-09-16T17:18:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/12943
dc.identifier.issn.none.fl_str_mv 0961-2033
dc.identifier.number.pt_BR.fl_str_mv v.15 n. 5
identifier_str_mv 0961-2033
v.15 n. 5
url http://www.repositorio.ufba.br/ri/handle/ri/12943
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1191/0961203306lu2295cr
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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