Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)

Detalhes bibliográficos
Autor(a) principal: Machado, Adelmir de Souza
Data de Publicação: 2005
Outros Autores: Galvão, T. S., Porto, Maria Aurélia da Fonseca, Figueiredo, J., Cruz Filho, Álvaro Augusto Souza da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6585
Resumo: Trabalho completo: acesso restrito, p. 379–384
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spelling Machado, Adelmir de SouzaGalvão, T. S.Porto, Maria Aurélia da FonsecaFigueiredo, J.Cruz Filho, Álvaro Augusto Souza daMachado, Adelmir de SouzaGalvão, T. S.Porto, Maria Aurélia da FonsecaFigueiredo, J.Cruz Filho, Álvaro Augusto Souza da2012-08-13T19:51:03Z20050105-4538http://www.repositorio.ufba.br/ri/handle/ri/6585v. 60, n. 3Trabalho completo: acesso restrito, p. 379–384Background:  A type 2 immune response, characterized by high levels of interleukin-4 and immunoglobulin E synthesis is a hallmark of respiratory allergic diseases. Individuals infected with human T-lymphotropic virus type I (HTLV-I) virus have spontaneous T-cell proliferation and increased interferon γ production, which are immunological functions associated with a type 1 immune response. Objective:  To determine the frequency of asthma and rhinitis symptoms and immediate skin reactivity to aeroallergens in HTLV-I infected individuals, compared with noninfected subjects. Methods:  Cross sectional study of 101 HTLV-I infected and 101 control uninfected blood donors, assessed by enzyme-linked immunosorbent assay and Western blot assays. The subjects were age and sex-matched, identified as presenting allergy history by questionnaire, which was complemented by a complete clinical examination and skin prick tests for aeroallergens. Results:  The frequency of atopy was lower in infected than uninfected subjects, 14.9 and 29.7% (P = 0.017), respectively. Skin reactivity to Dermatophagoides pteronissynus, Dermatophagoides farinae and Blomia tropicalis were the most frequently observed among all the tested antigens in both groups. Skin reactivity to histamine was also reduced in the infected individuals compared with uninfected subjects (medians 4.0 vs 5.0, respectively; P < 0.0001). Infection by HTLV-I was found to be a factor of protection to atopy (RP 0.44; P = 0.005). Conclusions:  The HTLV-I infection reduces the frequency of respiratory allergy and skin reactivity to aeroallergens.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-08-13T19:51:03Z No. of bitstreams: 1 (157).pdf: 256991 bytes, checksum: cf74995498c1431541fa116407107100 (MD5)Made available in DSpace on 2012-08-13T19:51:03Z (GMT). No. of bitstreams: 1 (157).pdf: 256991 bytes, checksum: cf74995498c1431541fa116407107100 (MD5) Previous issue date: 2005-03John Wiley and Sonshttp://dx.doi.org/10.1111/j.1398-9995.2005.00709.xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAallergyasthmaatopyhuman T-lymphotropic virus type IretrovirusrhinitisSkin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)Allergyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL(157).pdf(157).pdfapplication/pdf256991https://repositorio.ufba.br/bitstream/ri/6585/1/%28157%29.pdfcf74995498c1431541fa116407107100MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6585/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT(157).pdf.txt(157).pdf.txtExtracted texttext/plain30728https://repositorio.ufba.br/bitstream/ri/6585/3/%28157%29.pdf.txt17029ffbe383d94e4eca5cf4f4153f16MD53ri/65852022-10-17 23:44:23.706oai:repositorio.ufba.br:ri/6585VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIHJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBCgogICAgUGVsbyBwcm9jZXNzbyBkZSBzdWJtaXNz77+9byBkZSBkb2N1bWVudG9zLCBvIGF1dG9yIG91IHNldQpyZXByZXNlbnRhbnRlIGxlZ2FsLCBhbyBhY2VpdGFyIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBjb25jZWRlIGFvClJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSBvIGRpcmVpdG8KZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCAKZGUgcHJlc2VydmHvv73vv71vLiBFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIAphdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIGNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4gCgogICAgUGFyYSBvcyBkb2N1bWVudG9zIHB1YmxpY2Fkb3MgY29tIHJlcGFzc2UgZGUgZGlyZWl0b3MgZGUgZGlzdHJpYnVp77+977+9bywgZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEgZW50ZW5kZSBxdWU6IAoKICAgIE1hbnRlbmRvIG9zICBkaXJlaXRvcyBhdXRvcmFpcywgcmVwYXNzYWRvcyBhIHRlcmNlaXJvcywgZW0gY2FzbyAKZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8gcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIAppbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1h77+977+9ZXMgc29icmUgbyBkb2N1bWVudG8gKE1ldGFkYWRvcyBkZXNjcml0aXZvcykuCgogRGVzdGEgZm9ybWEsIGF0ZW5kZW5kbyBhb3MgYW5zZWlvcyBkZXNzYSB1bml2ZXJzaWRhZGUgCmVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gYXMgcmVzdHJp77+977+9ZXMgaW1wb3N0YXMgcGVsb3MgCmVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4gCgogICAgUGFyYSBhcyBwdWJsaWNh77+977+9ZXMgZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgCkFjZXNzbyBBYmVydG8sIG9zIGRlcO+/vXNpdG9zIGNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gCm9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudO+/vW0gbyBhY2Vzc28gaXJyZXN0cml0byBhbyBtZXRhZGFkb3MgCmUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIApjb25zZW50aW1lbnRvIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgCmVzdGFyZW0gZW0gaW5pY2lhdGl2YXMgZGUgYWNlc3NvIGFiZXJ0by4KCiAgICBFbSBhbWJvcyBvIGNhc28sIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBwb2RlIHNlciBhY2VpdG8gcGVsbyAKYXV0b3IsIGRldGVudG9yZXMgZGUgZGlyZWl0b3MgZS9vdSB0ZXJjZWlyb3MgYW1wYXJhZG9zIHBlbGEgCnVuaXZlcnNpZGFkZS4gRGV2aWRvIGFvcyBkaWZlcmVudGVzIHByb2Nlc3NvcyBwZWxvIHF1YWwgYSBzdWJtaXNz77+9byAKcG9kZSBvY29ycmVyLCBvIHJlcG9zaXTvv71yaW8gcGVybWl0ZSBhIGFjZWl0Ye+/ve+/vW8gZGEgbGljZW7vv71hIHBvciAKdGVyY2Vpcm9zLCBzb21lbnRlIG5vcyBjYXNvcyBkZSBkb2N1bWVudG9zIHByb2R1emlkb3MgcG9yIGludGVncmFudGVzIApkYSBVRkJBIGUgc3VibWV0aWRvcyBwb3IgcGVzc29hcyBhbXBhcmFkYXMgcG9yIGVzdGEgaW5zdGl0dWnvv73vv71vLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-10-18T02:44:23Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
dc.title.alternative.pt_BR.fl_str_mv Allergy
title Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
spellingShingle Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
Machado, Adelmir de Souza
allergy
asthma
atopy
human T-lymphotropic virus type I
retrovirus
rhinitis
title_short Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
title_full Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
title_fullStr Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
title_full_unstemmed Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
title_sort Skin reactivity to aeroallergens is reduced in human T-lymphotropic virus type I-infected healthy blood-donors (asymptomatic carriers)
author Machado, Adelmir de Souza
author_facet Machado, Adelmir de Souza
Galvão, T. S.
Porto, Maria Aurélia da Fonseca
Figueiredo, J.
Cruz Filho, Álvaro Augusto Souza da
author_role author
author2 Galvão, T. S.
Porto, Maria Aurélia da Fonseca
Figueiredo, J.
Cruz Filho, Álvaro Augusto Souza da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Machado, Adelmir de Souza
Galvão, T. S.
Porto, Maria Aurélia da Fonseca
Figueiredo, J.
Cruz Filho, Álvaro Augusto Souza da
Machado, Adelmir de Souza
Galvão, T. S.
Porto, Maria Aurélia da Fonseca
Figueiredo, J.
Cruz Filho, Álvaro Augusto Souza da
dc.subject.por.fl_str_mv allergy
asthma
atopy
human T-lymphotropic virus type I
retrovirus
rhinitis
topic allergy
asthma
atopy
human T-lymphotropic virus type I
retrovirus
rhinitis
description Trabalho completo: acesso restrito, p. 379–384
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2012-08-13T19:51:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6585
dc.identifier.issn.none.fl_str_mv 0105-4538
dc.identifier.number.pt_BR.fl_str_mv v. 60, n. 3
identifier_str_mv 0105-4538
v. 60, n. 3
url http://www.repositorio.ufba.br/ri/handle/ri/6585
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv John Wiley and Sons
publisher.none.fl_str_mv John Wiley and Sons
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1111/j.1398-9995.2005.00709.x
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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