Effect of propranolol on capsular reaction around silicone implants in guinea pigs

Detalhes bibliográficos
Autor(a) principal: Mesquita, Charles Jean Gomes de
Data de Publicação: 2015
Outros Autores: Guimarães, Sérgio Botelho, Leite Filho, José Alberto Dias, Maciel, Felipe Silva, Rocha, José Lima de Carvalho, Leite, José Alberto Dias
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/18143
Resumo: MESQUITA, Charles Jean Gomes de et al. Effect of propranolol on capsular reaction around silicone implants in guinea pigs. Acta Cirúrgica Brasileira, São Paulo, v. 30, n. 1, p. 24-33, jan. 2015.
id UFC-7_4bcf4aa9525a1f8819a914334f3cfca8
oai_identifier_str oai:repositorio.ufc.br:riufc/18143
network_acronym_str UFC-7
network_name_str Repositório Institucional da Universidade Federal do Ceará (UFC)
repository_id_str
spelling Effect of propranolol on capsular reaction around silicone implants in guinea pigsColágenoPropranololElastômeros de SiliconeMESQUITA, Charles Jean Gomes de et al. Effect of propranolol on capsular reaction around silicone implants in guinea pigs. Acta Cirúrgica Brasileira, São Paulo, v. 30, n. 1, p. 24-33, jan. 2015.PURPOSE: To evaluate the effect of propranolol on capsular architecture around silicone implants by measuring the inflammation, capsular thickness, and collagen fiber density, using a guinea pig experimental model. METHODS: Thirty six adult male guinea pigs randomly divided into two groups (n=18) were used. Each one received a silicone implant with textured-surface. The capsular tissue around implants from untreated or treated animals with the beta-adrenoceptor antagonist propranolol (10 mg/kg, dissolved in daily water) were analyzed for inflammation by histological scoring, capsular thickness by computerized histometry, and collagen fibers type I and Type III density by picrosirius polarization at different time points (7, 14 or 21 days after silicone implantation). RESULTS: Propranolol treatment reduced inflammation and impaired capsular thickness and delayed collagen maturation around the textured implant. CONCLUSION: Propranolol reduces the risk of developing capsular contracture around silicone implants with textured surface.Acta Cirúrgica Brasileira2016-07-05T11:55:59Z2016-07-05T11:55:59Z2015-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMESQUITA, C. J. G. ; GUIMARÃES, S. B. ; LEITE FILHO, J. A. D. ; MACIEL, F. S. ; ROCHA, J. L. C. ; LEITE, J. A. D. (2015)On-line version 1678-2674http://www.repositorio.ufc.br/handle/riufc/18143Mesquita, Charles Jean Gomes deGuimarães, Sérgio BotelhoLeite Filho, José Alberto DiasMaciel, Felipe SilvaRocha, José Lima de CarvalhoLeite, José Alberto Diasengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2016-07-05T11:55:59Zoai:repositorio.ufc.br:riufc/18143Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2024-09-11T18:25:28.346978Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.none.fl_str_mv Effect of propranolol on capsular reaction around silicone implants in guinea pigs
title Effect of propranolol on capsular reaction around silicone implants in guinea pigs
spellingShingle Effect of propranolol on capsular reaction around silicone implants in guinea pigs
Mesquita, Charles Jean Gomes de
Colágeno
Propranolol
Elastômeros de Silicone
title_short Effect of propranolol on capsular reaction around silicone implants in guinea pigs
title_full Effect of propranolol on capsular reaction around silicone implants in guinea pigs
title_fullStr Effect of propranolol on capsular reaction around silicone implants in guinea pigs
title_full_unstemmed Effect of propranolol on capsular reaction around silicone implants in guinea pigs
title_sort Effect of propranolol on capsular reaction around silicone implants in guinea pigs
author Mesquita, Charles Jean Gomes de
author_facet Mesquita, Charles Jean Gomes de
Guimarães, Sérgio Botelho
Leite Filho, José Alberto Dias
Maciel, Felipe Silva
Rocha, José Lima de Carvalho
Leite, José Alberto Dias
author_role author
author2 Guimarães, Sérgio Botelho
Leite Filho, José Alberto Dias
Maciel, Felipe Silva
Rocha, José Lima de Carvalho
Leite, José Alberto Dias
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mesquita, Charles Jean Gomes de
Guimarães, Sérgio Botelho
Leite Filho, José Alberto Dias
Maciel, Felipe Silva
Rocha, José Lima de Carvalho
Leite, José Alberto Dias
dc.subject.por.fl_str_mv Colágeno
Propranolol
Elastômeros de Silicone
topic Colágeno
Propranolol
Elastômeros de Silicone
description MESQUITA, Charles Jean Gomes de et al. Effect of propranolol on capsular reaction around silicone implants in guinea pigs. Acta Cirúrgica Brasileira, São Paulo, v. 30, n. 1, p. 24-33, jan. 2015.
publishDate 2015
dc.date.none.fl_str_mv 2015-01
2016-07-05T11:55:59Z
2016-07-05T11:55:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv MESQUITA, C. J. G. ; GUIMARÃES, S. B. ; LEITE FILHO, J. A. D. ; MACIEL, F. S. ; ROCHA, J. L. C. ; LEITE, J. A. D. (2015)
On-line version 1678-2674
http://www.repositorio.ufc.br/handle/riufc/18143
identifier_str_mv MESQUITA, C. J. G. ; GUIMARÃES, S. B. ; LEITE FILHO, J. A. D. ; MACIEL, F. S. ; ROCHA, J. L. C. ; LEITE, J. A. D. (2015)
On-line version 1678-2674
url http://www.repositorio.ufc.br/handle/riufc/18143
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Acta Cirúrgica Brasileira
publisher.none.fl_str_mv Acta Cirúrgica Brasileira
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade Federal do Ceará (UFC)
instname:Universidade Federal do Ceará (UFC)
instacron:UFC
instname_str Universidade Federal do Ceará (UFC)
instacron_str UFC
institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
repository.name.fl_str_mv Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)
repository.mail.fl_str_mv bu@ufc.br || repositorio@ufc.br
_version_ 1813028798144184320

Registros relacionados