Ontological fundamentals of the debate on genetic selection and gene editing
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Fractal : Revista de Psicologia |
Texto Completo: | https://periodicos.uff.br/fractal/article/view/5607 |
Resumo: | This study discusses the ontological assumptions assumed in the bioethical debate about human genetic selection and gene editing. With a view to managing genetic disorders, different therapies have been employed clinically and experimentally, since the 1990s. Among the treatment strategies, we find embryo selection (by means of pre-implantation genetic diagnosis) and gene therapy (by means of gene editing). The development of these techniques raises discussions about their ethical implications. This article postulates that different conceptions of humanity can be identified in these discussions, grounding ethical positions regarding genome interventions. The article seeks to analyze these conceptions, following three steps. First, the biomedical context of genetic selection and gene editing is presented. Then, discussions on the ethical aspects of these interventions are highlighted. Finally, different conceptions of humanity grounding these discussions are identified and analyzed, considering the notion of distributive justice. |
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Ontological fundamentals of the debate on genetic selection and gene editingFundamentos ontológicos do debate sobre seleção e edição do genomagenetic selectiongene editingbioethicsdistributive justicechaveseleção genéticaedição genéticabioéticajustiça distributivaThis study discusses the ontological assumptions assumed in the bioethical debate about human genetic selection and gene editing. With a view to managing genetic disorders, different therapies have been employed clinically and experimentally, since the 1990s. Among the treatment strategies, we find embryo selection (by means of pre-implantation genetic diagnosis) and gene therapy (by means of gene editing). The development of these techniques raises discussions about their ethical implications. This article postulates that different conceptions of humanity can be identified in these discussions, grounding ethical positions regarding genome interventions. The article seeks to analyze these conceptions, following three steps. First, the biomedical context of genetic selection and gene editing is presented. Then, discussions on the ethical aspects of these interventions are highlighted. Finally, different conceptions of humanity grounding these discussions are identified and analyzed, considering the notion of distributive justice.Este trabalho problematiza os pressupostos ontológicos assumidos no debate bioético sobre a seleção e edição do genoma humano. Com vistas ao manejo de desordens genéticas, diferentes terapêuticas têm sido empregadas clínica e experimentalmente, desde a década de 1990. Entre as estratégias de tratamento destacam-se a seleção de embriões (mediante diagnóstico genético pré-implantação) e a terapia gênica (mediante edição genética). O desenvolvimento destas técnicas suscita discussões acerca de suas implicações éticas. O presente artigo postula que distintas concepções de humanidade podem ser identificadas nas discussões, as quais fundamentam posicionamentos acerca de intervenções sobre o genoma da espécie. O artigo busca analisar essas concepções, percorrendo três passos. Primeiramente, apresenta-se o contexto biomédico de aplicação da seleção e edição do genoma humano. Em seguida, são evidenciadas discussões sobre os aspectos éticos de tais intervenções. Por fim, explicitam-se diferentes concepções de humanidade que fundamentam as referidas discussões, de maneira a problematizá-las, tendo em vista a noção de justiça distributiva.ABEC2022-08-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresapplication/pdfhttps://periodicos.uff.br/fractal/article/view/560710.22409/1984-0292/v32i2/5607Fractal: Journal of Psychology; Vol. 32 No. 2 (2020); 111-119Fractal: Revista de Psicologia; v. 32 n. 2 (2020); 111-1191984-029210.22409/1984-0292/v32i2reponame:Fractal : Revista de Psicologiainstname:Universidade Federal Fluminense (UFF)instacron:UFFporhttps://periodicos.uff.br/fractal/article/view/5607/32706Copyright (c) 2020 Copyright © 2020 Furtado, R. N.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessFurtado, Rafael Nogueira2020-06-16T21:22:37Zoai:ojs.pkp.sfu.ca:article/5607Revistahttps://periodicos.uff.br/fractalPUBhttps://periodicos.uff.br/fractal/oai||anaclmonteiro@yahoo.com.br|| mlivianascimento@gmail.com1984-02921984-0292opendoar:2020-06-16T21:22:37Fractal : Revista de Psicologia - Universidade Federal Fluminense (UFF)false |
dc.title.none.fl_str_mv |
Ontological fundamentals of the debate on genetic selection and gene editing Fundamentos ontológicos do debate sobre seleção e edição do genoma |
title |
Ontological fundamentals of the debate on genetic selection and gene editing |
spellingShingle |
Ontological fundamentals of the debate on genetic selection and gene editing Furtado, Rafael Nogueira genetic selection gene editing bioethics distributive justice chave seleção genética edição genética bioética justiça distributiva |
title_short |
Ontological fundamentals of the debate on genetic selection and gene editing |
title_full |
Ontological fundamentals of the debate on genetic selection and gene editing |
title_fullStr |
Ontological fundamentals of the debate on genetic selection and gene editing |
title_full_unstemmed |
Ontological fundamentals of the debate on genetic selection and gene editing |
title_sort |
Ontological fundamentals of the debate on genetic selection and gene editing |
author |
Furtado, Rafael Nogueira |
author_facet |
Furtado, Rafael Nogueira |
author_role |
author |
dc.contributor.author.fl_str_mv |
Furtado, Rafael Nogueira |
dc.subject.por.fl_str_mv |
genetic selection gene editing bioethics distributive justice chave seleção genética edição genética bioética justiça distributiva |
topic |
genetic selection gene editing bioethics distributive justice chave seleção genética edição genética bioética justiça distributiva |
description |
This study discusses the ontological assumptions assumed in the bioethical debate about human genetic selection and gene editing. With a view to managing genetic disorders, different therapies have been employed clinically and experimentally, since the 1990s. Among the treatment strategies, we find embryo selection (by means of pre-implantation genetic diagnosis) and gene therapy (by means of gene editing). The development of these techniques raises discussions about their ethical implications. This article postulates that different conceptions of humanity can be identified in these discussions, grounding ethical positions regarding genome interventions. The article seeks to analyze these conceptions, following three steps. First, the biomedical context of genetic selection and gene editing is presented. Then, discussions on the ethical aspects of these interventions are highlighted. Finally, different conceptions of humanity grounding these discussions are identified and analyzed, considering the notion of distributive justice. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado por pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.uff.br/fractal/article/view/5607 10.22409/1984-0292/v32i2/5607 |
url |
https://periodicos.uff.br/fractal/article/view/5607 |
identifier_str_mv |
10.22409/1984-0292/v32i2/5607 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.uff.br/fractal/article/view/5607/32706 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Copyright © 2020 Furtado, R. N. https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Copyright © 2020 Furtado, R. N. https://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
ABEC |
publisher.none.fl_str_mv |
ABEC |
dc.source.none.fl_str_mv |
Fractal: Journal of Psychology; Vol. 32 No. 2 (2020); 111-119 Fractal: Revista de Psicologia; v. 32 n. 2 (2020); 111-119 1984-0292 10.22409/1984-0292/v32i2 reponame:Fractal : Revista de Psicologia instname:Universidade Federal Fluminense (UFF) instacron:UFF |
instname_str |
Universidade Federal Fluminense (UFF) |
instacron_str |
UFF |
institution |
UFF |
reponame_str |
Fractal : Revista de Psicologia |
collection |
Fractal : Revista de Psicologia |
repository.name.fl_str_mv |
Fractal : Revista de Psicologia - Universidade Federal Fluminense (UFF) |
repository.mail.fl_str_mv |
||anaclmonteiro@yahoo.com.br|| mlivianascimento@gmail.com |
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