EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS

Detalhes bibliográficos
Autor(a) principal: Braga, Luziana Tavares
Data de Publicação: 2007
Outros Autores: Nunes-Pinheiro, Diana Célia Sousa, Sousa, Jacy Aurélia Vieira de, Silva, Francisco Martileudo Sousa, Farias, Viviane Moura, Leite, Ana Karine Rocha de Melo, Lopes, Cláudio Afonso Pinho, Facó, Olivardo, Campello, Cláudio Cabral, Costa, José Hélio, Nogueira, Teresa Neuma Albuquerque Gomes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Ciência animal brasileira (Online)
Texto Completo: https://revistas.ufg.br/vet/article/view/1353
Resumo: The aim of this work was to evaluate the effect of levamisole and ethanolic extract of Momordica charantia leaves on experimental dermatophytosis. Young rabbits, New Zealand, males, were divided in groups that received by via oral during 15 days Tween 20 (1%, control; n=5), levamisole (25 mg/kg/LP; n=4) or ethanolic extract of M. charantia leaves (EE, 10 mg/kg/LP; n=6), beginning at 15th day of Microsporum canis inoculation. Total and differential blood circulating leukocyte counts, cultive of skin and histopatological evaluation of the lesions were realized. Levamisole and EE reduced the histological eva¬luation scores of the lesions provoked by M. canis and did not change of the leukocyte counts. The treatment with levamisole promoted alterations in relation to the control (p
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spelling EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITSEFEITO DO LEVAMISOL E DO EXTRATO ETANÓLICO DE FOLHAS DE Momordica Charantia SOBRE A DERMATOFITOSE EXPERIMENTAL EM COELHOSThe aim of this work was to evaluate the effect of levamisole and ethanolic extract of Momordica charantia leaves on experimental dermatophytosis. Young rabbits, New Zealand, males, were divided in groups that received by via oral during 15 days Tween 20 (1%, control; n=5), levamisole (25 mg/kg/LP; n=4) or ethanolic extract of M. charantia leaves (EE, 10 mg/kg/LP; n=6), beginning at 15th day of Microsporum canis inoculation. Total and differential blood circulating leukocyte counts, cultive of skin and histopatological evaluation of the lesions were realized. Levamisole and EE reduced the histological eva¬luation scores of the lesions provoked by M. canis and did not change of the leukocyte counts. The treatment with levamisole promoted alterations in relation to the control (pO objetivo deste trabalho foi avaliar o efeito do levamisol e do extrato etanólico das folhas de Momordica charantia na dermatofitose experimental. Para tanto, coe¬lhos jovens, Nova Zelândia, machos, divididos em grupos, receberam, por via oral, durante quinze dias consecutivos Tween 20 (1%, controle; n=5), levamisol (25 mg/Kg/PV; n=4) ou extrato etanólico de M. charantia (EE, 10 mg/Kg/PV, n=6) a partir do 15º dia inoculação por Microsporum canis. Foram realizadas as contagens total e diferencial de leucócitos do sangue periférico, cultivo do raspado de pele e avaliação histopatológica das lesões. O levamisol e o EE reduziram os escores de avaliação histológica das lesões provocadas pelo M. canis e não induziram modificação dos leucócitos circulantes. O tratamento com levamisol provocou alterações na pele infectada em relação ao controle (pUniversidade Federal de Goiás2007-07-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresapplication/pdfhttps://revistas.ufg.br/vet/article/view/135310.5216/cab.v8i2.1353Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 8 No. 2 (2007); 285-296Ciência Animal Brasileira / Brazilian Animal Science; v. 8 n. 2 (2007); 285-2961809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/vet/article/view/1353/1409Braga, Luziana TavaresNunes-Pinheiro, Diana Célia SousaSousa, Jacy Aurélia Vieira deSilva, Francisco Martileudo SousaFarias, Viviane MouraLeite, Ana Karine Rocha de MeloLopes, Cláudio Afonso PinhoFacó, OlivardoCampello, Cláudio CabralCosta, José HélioNogueira, Teresa Neuma Albuquerque Gomesinfo:eu-repo/semantics/openAccess2007-07-25T17:43:57Zoai:ojs.revistas.ufg.br:article/1353Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:54:54.350220Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
EFEITO DO LEVAMISOL E DO EXTRATO ETANÓLICO DE FOLHAS DE Momordica Charantia SOBRE A DERMATOFITOSE EXPERIMENTAL EM COELHOS
title EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
spellingShingle EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
Braga, Luziana Tavares
title_short EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
title_full EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
title_fullStr EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
title_full_unstemmed EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
title_sort EFFECT OF THE LEVAMISOLE AND THE ETHANOLIC EXTRACT OF Momordica charantia LEAVES ON THE EXPERIMENTAL DERMATOPHYTOSIS IN RABBITS
author Braga, Luziana Tavares
author_facet Braga, Luziana Tavares
Nunes-Pinheiro, Diana Célia Sousa
Sousa, Jacy Aurélia Vieira de
Silva, Francisco Martileudo Sousa
Farias, Viviane Moura
Leite, Ana Karine Rocha de Melo
Lopes, Cláudio Afonso Pinho
Facó, Olivardo
Campello, Cláudio Cabral
Costa, José Hélio
Nogueira, Teresa Neuma Albuquerque Gomes
author_role author
author2 Nunes-Pinheiro, Diana Célia Sousa
Sousa, Jacy Aurélia Vieira de
Silva, Francisco Martileudo Sousa
Farias, Viviane Moura
Leite, Ana Karine Rocha de Melo
Lopes, Cláudio Afonso Pinho
Facó, Olivardo
Campello, Cláudio Cabral
Costa, José Hélio
Nogueira, Teresa Neuma Albuquerque Gomes
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Braga, Luziana Tavares
Nunes-Pinheiro, Diana Célia Sousa
Sousa, Jacy Aurélia Vieira de
Silva, Francisco Martileudo Sousa
Farias, Viviane Moura
Leite, Ana Karine Rocha de Melo
Lopes, Cláudio Afonso Pinho
Facó, Olivardo
Campello, Cláudio Cabral
Costa, José Hélio
Nogueira, Teresa Neuma Albuquerque Gomes
description The aim of this work was to evaluate the effect of levamisole and ethanolic extract of Momordica charantia leaves on experimental dermatophytosis. Young rabbits, New Zealand, males, were divided in groups that received by via oral during 15 days Tween 20 (1%, control; n=5), levamisole (25 mg/kg/LP; n=4) or ethanolic extract of M. charantia leaves (EE, 10 mg/kg/LP; n=6), beginning at 15th day of Microsporum canis inoculation. Total and differential blood circulating leukocyte counts, cultive of skin and histopatological evaluation of the lesions were realized. Levamisole and EE reduced the histological eva¬luation scores of the lesions provoked by M. canis and did not change of the leukocyte counts. The treatment with levamisole promoted alterations in relation to the control (p
publishDate 2007
dc.date.none.fl_str_mv 2007-07-05
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/vet/article/view/1353
10.5216/cab.v8i2.1353
url https://revistas.ufg.br/vet/article/view/1353
identifier_str_mv 10.5216/cab.v8i2.1353
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/vet/article/view/1353/1409
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Goiás
publisher.none.fl_str_mv Universidade Federal de Goiás
dc.source.none.fl_str_mv Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 8 No. 2 (2007); 285-296
Ciência Animal Brasileira / Brazilian Animal Science; v. 8 n. 2 (2007); 285-296
1809-6891
1518-2797
reponame:Ciência animal brasileira (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Ciência animal brasileira (Online)
collection Ciência animal brasileira (Online)
repository.name.fl_str_mv Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv ||revistacab@gmail.com
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