Prospecção fitoquímica e avaliação das atividades antimicrobiana e antioxidante de espécies de Arecaceae

• Autor(a) principal: Fabri, Rodrigo Luiz
• Data de Publicação: 2022
• Outros Autores: de Oliveira Lemos, Ari Sérgio, de Lima Paula, Priscila de Lima Paula, de Freitas Souza, Thalita, Gomes Ferreira, Thayná, Melo Campos, Lara, Torres Branca, Matheus
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: HU Revista (Online)
• Texto Completo: https://periodicos.ufjf.br/index.php/hurevista/article/view/37425
• topic: Arecaceae; Antioxidantes; Anti-infecciosos; Flavonoides; Extratos Vegetais

Introduction: The incidence of microorganisms resistant to conventional therapies awakens the need for development of new antimicrobials. Objective: In this study, we evaluated the antioxidant and antimicrobial activities of ethanolic extracts of Bactris gasipaes Kunth leaves (BGFoEt), Manicaria saccifera Gaertn. (MSFoEt), fruits and roots of Mauritia flexuosa L.f. (MFFrEt and MFREt), seeds of Ptychosperma pullenii Essig (PPSEt), pulp of Raphia vinifera P. Beauv. (RVPoEt), Syagrusschizophylla (Mart.) Glassman fruits (SSFrEt) and the aqueous extract of Areca catechu L. fruits. (ACFrAq). Materials and methods: Phytochemical analyses, determination of flavonoid content, determination of antioxidant potential, through phosphomolybdenum complex reduction, DPPH radical reduction and inhibition of β-carotene/linoleic acid system, and antimicrobial activity, through determination of minimum inhibitory concentration, were performed. Results: Phytochemical prospection revealed the presence of alkaloids, coumarins, tannins, triterpenes, steroids, flavonoids and anthraquinones. The total flavonoid content ranged from 17.9 to 76.2 mg/g rutin equivalent. The MSFoEt, RVPoEt, PPSEt and MFREt extracts showed significant results for phosphomolybdenum complex reduction (83±0.3; 106±1.8; 25±1.6 and 29±4.5 % of antioxidant activity relative to quercetin, respectively) and DPPH radical inhibition (CE50 of 1.0±0.2; 1.7±0.2; 8.4±0.7 and 3.8±0.3 μg/mL, respectively). For these extracts, the β-carotene/linoleic acid method was performed, with oxidation inhibition percentage of 49.0±2.6; 41.4±0.6; 45.0±1.9 and 51.4±1.7 %, respectively. As for antimicrobial activity, all extracts inhibited at least one microorganism, and MFREt obtained more promising results, especially for Enterococcus faecalis (MIC 8 μg/mL) and Klebsiella pneumoniae (MIC 16 μg/mL), respectively. Conclusion: Arecaceae species extracts revealed significant antioxidant and antimicrobial properties. Further studies are needed to understand the results found.