Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats.
Autor(a) principal: | |
---|---|
Data de Publicação: | 2009 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | HU Revista (Online) |
Texto Completo: | https://periodicos.ufjf.br/index.php/hurevista/article/view/43 |
Resumo: | Aims Evaluate body weight, food and water intakes, of Wistar rats on alendronate. Methods Thirty rats, divided in 3 groups of 10. The first group (control group) received saline, the second and third ones receiving alendronate 4mg and alendronate 0.033mg, respectively (gavage). Body weight and food and water intakes were measured daily for 10 days. Results From the first to the last day the mean body weight ranged from 188,2g (SD 7,3) to 183,2g (SD 5,7) in group A, from 183,0g (SD 7,7) to (177,5g (SD 8,2) in group B, and from 188,9g (SD 17,1) to 184,5 (SD 16,4) in group C. Mean food intake ranged from 15,0g (SD 1,8) to 17,5g (SD 1,1) in group A, from 14,0g (SD 2,2) to 15,4g (SD 2,6) in group B, and from 23,3g (SD 2,0) to 14,9g (SD 2,6) in group C. Mean water intake ranged from 17,0ml (SD 6,5) to 20,6ml (SD 5,6) in group A, from 20,8ml (SD 1,3) to 22,1ml (SD 3,6) in group B, and from 16,0ml (SD 5,7) to 19,3ml (SD 2,7) in group C. Conclusions Alendronate caused significant difference in body weight (higher the dose lesser the weight) and water intake (control group consumed less water). No difference regarding food intake. |
id |
UFJF-8_6fe3012821b6db8128fd5c1ecac763aa |
---|---|
oai_identifier_str |
oai:periodicos.ufjf.br:article/43 |
network_acronym_str |
UFJF-8 |
network_name_str |
HU Revista (Online) |
repository_id_str |
|
spelling |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats.Effects of sodium alendronate on body weight and water and food intake of adult female Wistar ratsAlendronate. Rats. Weight Gain. Diet.Aims Evaluate body weight, food and water intakes, of Wistar rats on alendronate. Methods Thirty rats, divided in 3 groups of 10. The first group (control group) received saline, the second and third ones receiving alendronate 4mg and alendronate 0.033mg, respectively (gavage). Body weight and food and water intakes were measured daily for 10 days. Results From the first to the last day the mean body weight ranged from 188,2g (SD 7,3) to 183,2g (SD 5,7) in group A, from 183,0g (SD 7,7) to (177,5g (SD 8,2) in group B, and from 188,9g (SD 17,1) to 184,5 (SD 16,4) in group C. Mean food intake ranged from 15,0g (SD 1,8) to 17,5g (SD 1,1) in group A, from 14,0g (SD 2,2) to 15,4g (SD 2,6) in group B, and from 23,3g (SD 2,0) to 14,9g (SD 2,6) in group C. Mean water intake ranged from 17,0ml (SD 6,5) to 20,6ml (SD 5,6) in group A, from 20,8ml (SD 1,3) to 22,1ml (SD 3,6) in group B, and from 16,0ml (SD 5,7) to 19,3ml (SD 2,7) in group C. Conclusions Alendronate caused significant difference in body weight (higher the dose lesser the weight) and water intake (control group consumed less water). No difference regarding food intake. This study aimed to assess the body weight and food and water intake of alendronate-treated Wistar rats. Thirty rats were divided in 3 groups of 10. Group A (control group) received saline, and Groups B and C received alendronate 4mg and alendronate 0.033mg, respectively through gavage. Body weight and food and water intake were measured daily for 10 days. From the first to the last day, the mean body weight ranged from 188.2g (SD 7.3) to 183.2g (SD 5.7) in Group A, from 183.0g (SD 7.7) to 177.5g (SD 8.2) in Group B, and from 188.9g (SD 17.1) to 184.5 (SD 16.4) in Group C. Mean food intake ranged from 15.0g (SD 1.8) to 17.5g (SD 1.1) in Group A, from 14.0g (SD 2.2) to 15.4g (SD 2.6) in Group B, and from 23.3g (SD 2.0) to 14.9g (SD 2.6) in Group C. Mean water intake ranged from 17.0ml (SD 6.5) to 20.6ml (SD 5.6) in Group A, from 20.8ml (SD 1.3) to 22.1ml (SD 3.6) in Group B, and from 16.0ml (SD 5.7) to 19.3ml (SD 2.7) in Group C. Alendronate caused significant differences in body weight (the higher the dose the lower the weight) and water intake (the control group consumed less water). No difference regarding food intake was found.Editora UFJF2009-08-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtOrPesquisa experimentalapplication/pdfhttps://periodicos.ufjf.br/index.php/hurevista/article/view/43HU Revista; v. 35 n. 1 (2009)1982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/43/207Fraga, Rafael OliveiraBertges, Luiz Carlosinfo:eu-repo/semantics/openAccess2023-05-04T03:53:15Zoai:periodicos.ufjf.br:article/43Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2023-05-04T03:53:15HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false |
dc.title.none.fl_str_mv |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. Effects of sodium alendronate on body weight and water and food intake of adult female Wistar rats |
title |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. |
spellingShingle |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. Fraga, Rafael Oliveira Alendronate. Rats. Weight Gain. Diet. |
title_short |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. |
title_full |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. |
title_fullStr |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. |
title_full_unstemmed |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. |
title_sort |
Effects of sodium alendronate on body weight, water and food intakes in adult female wistar rats. |
author |
Fraga, Rafael Oliveira |
author_facet |
Fraga, Rafael Oliveira Bertges, Luiz Carlos |
author_role |
author |
author2 |
Bertges, Luiz Carlos |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Fraga, Rafael Oliveira Bertges, Luiz Carlos |
dc.subject.por.fl_str_mv |
Alendronate. Rats. Weight Gain. Diet. |
topic |
Alendronate. Rats. Weight Gain. Diet. |
description |
Aims Evaluate body weight, food and water intakes, of Wistar rats on alendronate. Methods Thirty rats, divided in 3 groups of 10. The first group (control group) received saline, the second and third ones receiving alendronate 4mg and alendronate 0.033mg, respectively (gavage). Body weight and food and water intakes were measured daily for 10 days. Results From the first to the last day the mean body weight ranged from 188,2g (SD 7,3) to 183,2g (SD 5,7) in group A, from 183,0g (SD 7,7) to (177,5g (SD 8,2) in group B, and from 188,9g (SD 17,1) to 184,5 (SD 16,4) in group C. Mean food intake ranged from 15,0g (SD 1,8) to 17,5g (SD 1,1) in group A, from 14,0g (SD 2,2) to 15,4g (SD 2,6) in group B, and from 23,3g (SD 2,0) to 14,9g (SD 2,6) in group C. Mean water intake ranged from 17,0ml (SD 6,5) to 20,6ml (SD 5,6) in group A, from 20,8ml (SD 1,3) to 22,1ml (SD 3,6) in group B, and from 16,0ml (SD 5,7) to 19,3ml (SD 2,7) in group C. Conclusions Alendronate caused significant difference in body weight (higher the dose lesser the weight) and water intake (control group consumed less water). No difference regarding food intake. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-20 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ArtOr Pesquisa experimental |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufjf.br/index.php/hurevista/article/view/43 |
url |
https://periodicos.ufjf.br/index.php/hurevista/article/view/43 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufjf.br/index.php/hurevista/article/view/43/207 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora UFJF |
publisher.none.fl_str_mv |
Editora UFJF |
dc.source.none.fl_str_mv |
HU Revista; v. 35 n. 1 (2009) 1982-8047 0103-3123 reponame:HU Revista (Online) instname:Universidade Federal de Juiz de Fora (UFJF) instacron:UFJF |
instname_str |
Universidade Federal de Juiz de Fora (UFJF) |
instacron_str |
UFJF |
institution |
UFJF |
reponame_str |
HU Revista (Online) |
collection |
HU Revista (Online) |
repository.name.fl_str_mv |
HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF) |
repository.mail.fl_str_mv |
revista.hurevista@ufjf.edu.br |
_version_ |
1796798239322669056 |