Oral microbiota versus oral mucositis during cancer treatment: a review

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Izabella Henrichs
Data de Publicação: 2020
Outros Autores: Ferigatto, Júlia, Cesar, Dionéia Evangelista, Fabri, Rodrigo Luiz, Apolônio, Ana Carolina Morais
Tipo de documento: Artigo
Idioma: por
Título da fonte: HU Revista (Online)
Texto Completo: https://periodicos.ufjf.br/index.php/hurevista/article/view/28995
Resumo: Introduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required.
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spelling Oral microbiota versus oral mucositis during cancer treatment: a reviewMicrobiota bucal versus mucosite oral durante o tratamento para o câncer: uma revisãoStomatitesOral microbiotaHead and Neck NeoplamsEstomatiteMicrobiota bucalNeoplasias de Cabeça e PescoçoIntroduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required.Introdução: A microbiota bucal tem sido associada à mucosite oral que ocorre durante a terapia para o câncer apesar de não haver consenso.  Objectivo: Este estudo objetivou estabelecer por meio de uma revisão da literatura a associação entre a microbiota bucal e a mucosite oral durante a Terapia para o Câncer de Cabeça e Pescoço (TCCP). Material e métodos: Foi realizada uma busca na base de dados PubMed no período de 2008-2018 utilizando-se as palavras chave “oral mucositis” e “oral microbiota” nos subtítulos “etiology” e “microbiology” do descritor “Head and Neck Neoplasms” da base Medical Subject Heading (MeSH). A questão norteadora do estudo foi: “Ocorre uma disbiose durante a terapia para o câncer de cabeça e pescoço que esteja associada à mucosite oral?”. Resultados: 22 artigos foram selecionados em duas etapas de extração dos dados: artigos que avaliaram a microbiota bucal durante TCCP (n=13), e artigos que também focaram na mucosite oral (n=9). Conclusão: A evidência apresentada na literatura sugere associação de uma disbiose da microbiota bucal com a progressão e agravamento da mucosite oral induzida pela radiação. Entretanto, novos estudos padronizados são necessários para se definir o core microbiano para a doença.Editora UFJF2020-04-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtRevLitapplication/pdfhttps://periodicos.ufjf.br/index.php/hurevista/article/view/2899510.34019/1982-8047.2020.v46.28995HU Revista; v. 46 (2020); 1-91982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/28995/20326Copyright (c) 2020 Izabella Henrichs Ribeiro, Júlia Ferigatto, Dionéia Evangelista Cesar, Rodrigo Luiz Fabri, Ana Carolina Morais Apolônioinfo:eu-repo/semantics/openAccessRibeiro, Izabella Henrichs Ferigatto, Júlia Cesar, Dionéia Evangelista Fabri, Rodrigo Luiz Apolônio, Ana Carolina Morais2020-05-26T12:54:12Zoai:periodicos.ufjf.br:article/28995Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2020-05-26T12:54:12HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false
dc.title.none.fl_str_mv Oral microbiota versus oral mucositis during cancer treatment: a review
Microbiota bucal versus mucosite oral durante o tratamento para o câncer: uma revisão
title Oral microbiota versus oral mucositis during cancer treatment: a review
spellingShingle Oral microbiota versus oral mucositis during cancer treatment: a review
Ribeiro, Izabella Henrichs
Stomatites
Oral microbiota
Head and Neck Neoplams
Estomatite
Microbiota bucal
Neoplasias de Cabeça e Pescoço
title_short Oral microbiota versus oral mucositis during cancer treatment: a review
title_full Oral microbiota versus oral mucositis during cancer treatment: a review
title_fullStr Oral microbiota versus oral mucositis during cancer treatment: a review
title_full_unstemmed Oral microbiota versus oral mucositis during cancer treatment: a review
title_sort Oral microbiota versus oral mucositis during cancer treatment: a review
author Ribeiro, Izabella Henrichs
author_facet Ribeiro, Izabella Henrichs
Ferigatto, Júlia
Cesar, Dionéia Evangelista
Fabri, Rodrigo Luiz
Apolônio, Ana Carolina Morais
author_role author
author2 Ferigatto, Júlia
Cesar, Dionéia Evangelista
Fabri, Rodrigo Luiz
Apolônio, Ana Carolina Morais
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Izabella Henrichs
Ferigatto, Júlia
Cesar, Dionéia Evangelista
Fabri, Rodrigo Luiz
Apolônio, Ana Carolina Morais
dc.subject.por.fl_str_mv Stomatites
Oral microbiota
Head and Neck Neoplams
Estomatite
Microbiota bucal
Neoplasias de Cabeça e Pescoço
topic Stomatites
Oral microbiota
Head and Neck Neoplams
Estomatite
Microbiota bucal
Neoplasias de Cabeça e Pescoço
description Introduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/28995
10.34019/1982-8047.2020.v46.28995
url https://periodicos.ufjf.br/index.php/hurevista/article/view/28995
identifier_str_mv 10.34019/1982-8047.2020.v46.28995
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufjf.br/index.php/hurevista/article/view/28995/20326
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editora UFJF
publisher.none.fl_str_mv Editora UFJF
dc.source.none.fl_str_mv HU Revista; v. 46 (2020); 1-9
1982-8047
0103-3123
reponame:HU Revista (Online)
instname:Universidade Federal de Juiz de Fora (UFJF)
instacron:UFJF
instname_str Universidade Federal de Juiz de Fora (UFJF)
instacron_str UFJF
institution UFJF
reponame_str HU Revista (Online)
collection HU Revista (Online)
repository.name.fl_str_mv HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)
repository.mail.fl_str_mv revista.hurevista@ufjf.edu.br
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