Oral microbiota versus oral mucositis during cancer treatment: a review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | HU Revista (Online) |
Texto Completo: | https://periodicos.ufjf.br/index.php/hurevista/article/view/28995 |
Resumo: | Introduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required. |
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Oral microbiota versus oral mucositis during cancer treatment: a reviewMicrobiota bucal versus mucosite oral durante o tratamento para o câncer: uma revisãoStomatitesOral microbiotaHead and Neck NeoplamsEstomatiteMicrobiota bucalNeoplasias de Cabeça e PescoçoIntroduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required.Introdução: A microbiota bucal tem sido associada à mucosite oral que ocorre durante a terapia para o câncer apesar de não haver consenso. Objectivo: Este estudo objetivou estabelecer por meio de uma revisão da literatura a associação entre a microbiota bucal e a mucosite oral durante a Terapia para o Câncer de Cabeça e Pescoço (TCCP). Material e métodos: Foi realizada uma busca na base de dados PubMed no período de 2008-2018 utilizando-se as palavras chave “oral mucositis” e “oral microbiota” nos subtítulos “etiology” e “microbiology” do descritor “Head and Neck Neoplasms” da base Medical Subject Heading (MeSH). A questão norteadora do estudo foi: “Ocorre uma disbiose durante a terapia para o câncer de cabeça e pescoço que esteja associada à mucosite oral?”. Resultados: 22 artigos foram selecionados em duas etapas de extração dos dados: artigos que avaliaram a microbiota bucal durante TCCP (n=13), e artigos que também focaram na mucosite oral (n=9). Conclusão: A evidência apresentada na literatura sugere associação de uma disbiose da microbiota bucal com a progressão e agravamento da mucosite oral induzida pela radiação. Entretanto, novos estudos padronizados são necessários para se definir o core microbiano para a doença.Editora UFJF2020-04-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtRevLitapplication/pdfhttps://periodicos.ufjf.br/index.php/hurevista/article/view/2899510.34019/1982-8047.2020.v46.28995HU Revista; v. 46 (2020); 1-91982-80470103-3123reponame:HU Revista (Online)instname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFporhttps://periodicos.ufjf.br/index.php/hurevista/article/view/28995/20326Copyright (c) 2020 Izabella Henrichs Ribeiro, Júlia Ferigatto, Dionéia Evangelista Cesar, Rodrigo Luiz Fabri, Ana Carolina Morais Apolônioinfo:eu-repo/semantics/openAccessRibeiro, Izabella Henrichs Ferigatto, Júlia Cesar, Dionéia Evangelista Fabri, Rodrigo Luiz Apolônio, Ana Carolina Morais2020-05-26T12:54:12Zoai:periodicos.ufjf.br:article/28995Revistahttps://periodicos.ufjf.br/index.php/hurevistaPUBhttps://periodicos.ufjf.br/index.php/hurevista/oairevista.hurevista@ufjf.edu.br1982-80470103-3123opendoar:2020-05-26T12:54:12HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF)false |
dc.title.none.fl_str_mv |
Oral microbiota versus oral mucositis during cancer treatment: a review Microbiota bucal versus mucosite oral durante o tratamento para o câncer: uma revisão |
title |
Oral microbiota versus oral mucositis during cancer treatment: a review |
spellingShingle |
Oral microbiota versus oral mucositis during cancer treatment: a review Ribeiro, Izabella Henrichs Stomatites Oral microbiota Head and Neck Neoplams Estomatite Microbiota bucal Neoplasias de Cabeça e Pescoço |
title_short |
Oral microbiota versus oral mucositis during cancer treatment: a review |
title_full |
Oral microbiota versus oral mucositis during cancer treatment: a review |
title_fullStr |
Oral microbiota versus oral mucositis during cancer treatment: a review |
title_full_unstemmed |
Oral microbiota versus oral mucositis during cancer treatment: a review |
title_sort |
Oral microbiota versus oral mucositis during cancer treatment: a review |
author |
Ribeiro, Izabella Henrichs |
author_facet |
Ribeiro, Izabella Henrichs Ferigatto, Júlia Cesar, Dionéia Evangelista Fabri, Rodrigo Luiz Apolônio, Ana Carolina Morais |
author_role |
author |
author2 |
Ferigatto, Júlia Cesar, Dionéia Evangelista Fabri, Rodrigo Luiz Apolônio, Ana Carolina Morais |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ribeiro, Izabella Henrichs Ferigatto, Júlia Cesar, Dionéia Evangelista Fabri, Rodrigo Luiz Apolônio, Ana Carolina Morais |
dc.subject.por.fl_str_mv |
Stomatites Oral microbiota Head and Neck Neoplams Estomatite Microbiota bucal Neoplasias de Cabeça e Pescoço |
topic |
Stomatites Oral microbiota Head and Neck Neoplams Estomatite Microbiota bucal Neoplasias de Cabeça e Pescoço |
description |
Introduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04-08 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ArtRevLit |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufjf.br/index.php/hurevista/article/view/28995 10.34019/1982-8047.2020.v46.28995 |
url |
https://periodicos.ufjf.br/index.php/hurevista/article/view/28995 |
identifier_str_mv |
10.34019/1982-8047.2020.v46.28995 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufjf.br/index.php/hurevista/article/view/28995/20326 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora UFJF |
publisher.none.fl_str_mv |
Editora UFJF |
dc.source.none.fl_str_mv |
HU Revista; v. 46 (2020); 1-9 1982-8047 0103-3123 reponame:HU Revista (Online) instname:Universidade Federal de Juiz de Fora (UFJF) instacron:UFJF |
instname_str |
Universidade Federal de Juiz de Fora (UFJF) |
instacron_str |
UFJF |
institution |
UFJF |
reponame_str |
HU Revista (Online) |
collection |
HU Revista (Online) |
repository.name.fl_str_mv |
HU Revista (Online) - Universidade Federal de Juiz de Fora (UFJF) |
repository.mail.fl_str_mv |
revista.hurevista@ufjf.edu.br |
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