Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | https://www.mdpi.com/2223-7747/11/23/3298 http://repositorio.ufla.br/jspui/handle/1/59558 |
Resumo: | The use of formulations containing botanical products for controlling insects that vector human and animal diseases has increased in recent years. Plant extracts seem to offer fewer risks to the environment and to human health without reducing the application strategy’s efficacy when compared to synthetic and conventional insecticides and repellents. Here, we evaluated the potential of extracts obtained from caninana, Chiococca alba (L.) Hitchc. (Rubiaceae), plants as a tool to be integrated into the management of Aedes aegypti, one of the principal vectors for the transmission of arborviruses in humans. We assessed the larvicidal and repellence performance against adult mosquitoes and evaluated the potential undesired effects of the extracts on non-target organisms. We assessed the susceptibility and predatory abilities of the nymphs of Belostoma anurum, a naturally occurring mosquito larva predator, and evaluated the C. alba extract’s cytotoxic effects in mammalian cell lines. Our chromatographic analysis revealed 18 compounds, including rutin, naringin, myricetin, morin, and quercetin. The methanolic extracts of C. alba showed larvicidal (LC50 = 82 (72–94) mg/mL) activity without killing or affecting the abilities of B. anurum to prey upon mosquito larvae. Our in silico predictions revealed the molecular interactions between rutin and the AeagOBP1 receptor to be one possible mechanism for the repellent potential recorded for formulations containing C. alba extracts. Low cytotoxicity against mammalian cell lines reinforces the selectivity of C. alba extracts. Collectively, our findings highlight the potential of C. alba and one of its constituents (rutin) as alternative tools to be integrated into the management of A. aegypti mosquitoes. |
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Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organismsPesticidas botânicosManejo de Aedes aegyptiAtividade larvicidaExtratos vegetaisInseticidas naturaisBotanical pesticidesAedes aegypti managementLarvicidal activityPlant extractsNatural insecticidesThe use of formulations containing botanical products for controlling insects that vector human and animal diseases has increased in recent years. Plant extracts seem to offer fewer risks to the environment and to human health without reducing the application strategy’s efficacy when compared to synthetic and conventional insecticides and repellents. Here, we evaluated the potential of extracts obtained from caninana, Chiococca alba (L.) Hitchc. (Rubiaceae), plants as a tool to be integrated into the management of Aedes aegypti, one of the principal vectors for the transmission of arborviruses in humans. We assessed the larvicidal and repellence performance against adult mosquitoes and evaluated the potential undesired effects of the extracts on non-target organisms. We assessed the susceptibility and predatory abilities of the nymphs of Belostoma anurum, a naturally occurring mosquito larva predator, and evaluated the C. alba extract’s cytotoxic effects in mammalian cell lines. Our chromatographic analysis revealed 18 compounds, including rutin, naringin, myricetin, morin, and quercetin. The methanolic extracts of C. alba showed larvicidal (LC50 = 82 (72–94) mg/mL) activity without killing or affecting the abilities of B. anurum to prey upon mosquito larvae. Our in silico predictions revealed the molecular interactions between rutin and the AeagOBP1 receptor to be one possible mechanism for the repellent potential recorded for formulations containing C. alba extracts. Low cytotoxicity against mammalian cell lines reinforces the selectivity of C. alba extracts. Collectively, our findings highlight the potential of C. alba and one of its constituents (rutin) as alternative tools to be integrated into the management of A. aegypti mosquitoes.Multidisciplinary Digital Publishing Institute (MDPI)2024-10-09T14:37:52Z2024-10-09T14:37:52Z2022-11-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBORGES, J. C. M.; HADDI, K.; VALBON, W. R.; COSTA, L. T. M.; ASCÊNCIO, S. D.; SANTOS, G. R.; SOARES, I. M.; BARBOSA, R. S.; VIANA, K. F.; SILVA, E. A. P.; MOURA, W. S.; ANDRADE, B. S.; OLIVEIRA, E. E.; AGUIAR, R. W. S. Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms. Plants, Basel, v. 11, p. 3298, 2022. Disponível em: https://doi.org/10.3390/plants11233298. Acesso em: 9 out. 2024.https://www.mdpi.com/2223-7747/11/23/3298http://repositorio.ufla.br/jspui/handle/1/59558Plantsreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessOliveira, Natália LeiteOliveira, Ana Carolina Salgado deSilva, Sergio HenriqueRodrigues, Adrise AparecidaBorges, Soraia VilelaOliveira, Juliano Elvis deResende, Jaime Vilela depor2024-10-09T17:46:54Zoai:localhost:1/59558Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2024-10-09T17:46:54Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
title |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
spellingShingle |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms Oliveira, Natália Leite Pesticidas botânicos Manejo de Aedes aegypti Atividade larvicida Extratos vegetais Inseticidas naturais Botanical pesticides Aedes aegypti management Larvicidal activity Plant extracts Natural insecticides |
title_short |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
title_full |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
title_fullStr |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
title_full_unstemmed |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
title_sort |
Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms |
author |
Oliveira, Natália Leite |
author_facet |
Oliveira, Natália Leite Oliveira, Ana Carolina Salgado de Silva, Sergio Henrique Rodrigues, Adrise Aparecida Borges, Soraia Vilela Oliveira, Juliano Elvis de Resende, Jaime Vilela de |
author_role |
author |
author2 |
Oliveira, Ana Carolina Salgado de Silva, Sergio Henrique Rodrigues, Adrise Aparecida Borges, Soraia Vilela Oliveira, Juliano Elvis de Resende, Jaime Vilela de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Natália Leite Oliveira, Ana Carolina Salgado de Silva, Sergio Henrique Rodrigues, Adrise Aparecida Borges, Soraia Vilela Oliveira, Juliano Elvis de Resende, Jaime Vilela de |
dc.subject.por.fl_str_mv |
Pesticidas botânicos Manejo de Aedes aegypti Atividade larvicida Extratos vegetais Inseticidas naturais Botanical pesticides Aedes aegypti management Larvicidal activity Plant extracts Natural insecticides |
topic |
Pesticidas botânicos Manejo de Aedes aegypti Atividade larvicida Extratos vegetais Inseticidas naturais Botanical pesticides Aedes aegypti management Larvicidal activity Plant extracts Natural insecticides |
description |
The use of formulations containing botanical products for controlling insects that vector human and animal diseases has increased in recent years. Plant extracts seem to offer fewer risks to the environment and to human health without reducing the application strategy’s efficacy when compared to synthetic and conventional insecticides and repellents. Here, we evaluated the potential of extracts obtained from caninana, Chiococca alba (L.) Hitchc. (Rubiaceae), plants as a tool to be integrated into the management of Aedes aegypti, one of the principal vectors for the transmission of arborviruses in humans. We assessed the larvicidal and repellence performance against adult mosquitoes and evaluated the potential undesired effects of the extracts on non-target organisms. We assessed the susceptibility and predatory abilities of the nymphs of Belostoma anurum, a naturally occurring mosquito larva predator, and evaluated the C. alba extract’s cytotoxic effects in mammalian cell lines. Our chromatographic analysis revealed 18 compounds, including rutin, naringin, myricetin, morin, and quercetin. The methanolic extracts of C. alba showed larvicidal (LC50 = 82 (72–94) mg/mL) activity without killing or affecting the abilities of B. anurum to prey upon mosquito larvae. Our in silico predictions revealed the molecular interactions between rutin and the AeagOBP1 receptor to be one possible mechanism for the repellent potential recorded for formulations containing C. alba extracts. Low cytotoxicity against mammalian cell lines reinforces the selectivity of C. alba extracts. Collectively, our findings highlight the potential of C. alba and one of its constituents (rutin) as alternative tools to be integrated into the management of A. aegypti mosquitoes. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-29 2024-10-09T14:37:52Z 2024-10-09T14:37:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
BORGES, J. C. M.; HADDI, K.; VALBON, W. R.; COSTA, L. T. M.; ASCÊNCIO, S. D.; SANTOS, G. R.; SOARES, I. M.; BARBOSA, R. S.; VIANA, K. F.; SILVA, E. A. P.; MOURA, W. S.; ANDRADE, B. S.; OLIVEIRA, E. E.; AGUIAR, R. W. S. Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms. Plants, Basel, v. 11, p. 3298, 2022. Disponível em: https://doi.org/10.3390/plants11233298. Acesso em: 9 out. 2024. https://www.mdpi.com/2223-7747/11/23/3298 http://repositorio.ufla.br/jspui/handle/1/59558 |
identifier_str_mv |
BORGES, J. C. M.; HADDI, K.; VALBON, W. R.; COSTA, L. T. M.; ASCÊNCIO, S. D.; SANTOS, G. R.; SOARES, I. M.; BARBOSA, R. S.; VIANA, K. F.; SILVA, E. A. P.; MOURA, W. S.; ANDRADE, B. S.; OLIVEIRA, E. E.; AGUIAR, R. W. S. Methanolic extracts of Chiococca alba in Aedes aegypti biorational management: larvicidal and repellent potential, and selectivity against non-target organisms. Plants, Basel, v. 11, p. 3298, 2022. Disponível em: https://doi.org/10.3390/plants11233298. Acesso em: 9 out. 2024. |
url |
https://www.mdpi.com/2223-7747/11/23/3298 http://repositorio.ufla.br/jspui/handle/1/59558 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute (MDPI) |
publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute (MDPI) |
dc.source.none.fl_str_mv |
Plants reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
instname_str |
Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
collection |
Repositório Institucional da UFLA |
repository.name.fl_str_mv |
Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
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1815438932142194688 |