Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog

Detalhes bibliográficos
Autor(a) principal: Sousa,C.P
Data de Publicação: 2011
Outros Autores: Nery,F, Azevedo,J.T, Viegas,C.A, Gomes,M.E, Dias,I.R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000100007
Resumo: Values of serum tartrate-resistant acid phosphatase ( TRAP) activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to study their relationship with serum minerals, namely calcium (Ca), phosphorous (P), and magnesium (Mg). The serum TRAP activity was 2.19±0.56IU/mL, with intra-individual variation of 18.3% and inter-individual variation of 25.6%. Significant correlations were observed between serum TRAP activity and Ca (r=-0.3431; P<0.05), Ca and Mg (r=-0.787; P<0.01), and TRAP and Mg (r=0.397; P<0.05). The results indicate that serum TRAP activity in dog could be of great value in research and in clinical practice, providing complementary non-invasive information on bone metabolism
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spelling Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dogdogbone metabolismbone resorptionosteoclastValues of serum tartrate-resistant acid phosphatase ( TRAP) activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to study their relationship with serum minerals, namely calcium (Ca), phosphorous (P), and magnesium (Mg). The serum TRAP activity was 2.19±0.56IU/mL, with intra-individual variation of 18.3% and inter-individual variation of 25.6%. Significant correlations were observed between serum TRAP activity and Ca (r=-0.3431; P<0.05), Ca and Mg (r=-0.787; P<0.01), and TRAP and Mg (r=0.397; P<0.05). The results indicate that serum TRAP activity in dog could be of great value in research and in clinical practice, providing complementary non-invasive information on bone metabolismUniversidade Federal de Minas Gerais, Escola de Veterinária2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000100007Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.63 n.1 2011reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352011000100007info:eu-repo/semantics/openAccessSousa,C.PNery,FAzevedo,J.TViegas,C.AGomes,M.EDias,I.Reng2011-04-08T00:00:00Zoai:scielo:S0102-09352011000100007Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2011-04-08T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
title Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
spellingShingle Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
Sousa,C.P
dog
bone metabolism
bone resorption
osteoclast
title_short Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
title_full Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
title_fullStr Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
title_full_unstemmed Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
title_sort Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
author Sousa,C.P
author_facet Sousa,C.P
Nery,F
Azevedo,J.T
Viegas,C.A
Gomes,M.E
Dias,I.R
author_role author
author2 Nery,F
Azevedo,J.T
Viegas,C.A
Gomes,M.E
Dias,I.R
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa,C.P
Nery,F
Azevedo,J.T
Viegas,C.A
Gomes,M.E
Dias,I.R
dc.subject.por.fl_str_mv dog
bone metabolism
bone resorption
osteoclast
topic dog
bone metabolism
bone resorption
osteoclast
description Values of serum tartrate-resistant acid phosphatase ( TRAP) activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to study their relationship with serum minerals, namely calcium (Ca), phosphorous (P), and magnesium (Mg). The serum TRAP activity was 2.19±0.56IU/mL, with intra-individual variation of 18.3% and inter-individual variation of 25.6%. Significant correlations were observed between serum TRAP activity and Ca (r=-0.3431; P<0.05), Ca and Mg (r=-0.787; P<0.01), and TRAP and Mg (r=0.397; P<0.05). The results indicate that serum TRAP activity in dog could be of great value in research and in clinical practice, providing complementary non-invasive information on bone metabolism
publishDate 2011
dc.date.none.fl_str_mv 2011-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000100007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000100007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-09352011000100007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.63 n.1 2011
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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