Bone turnover markers in sheep and goat: A review of the scientific literature
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais da Academia Brasileira de Ciências (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231 |
Resumo: | ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants. |
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Anais da Academia Brasileira de Ciências (Online) |
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Bone turnover markers in sheep and goat: A review of the scientific literatureBone formation markersbone resorption markersbone metabolismsmall ruminants.ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants.Academia Brasileira de Ciências2017-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231Anais da Academia Brasileira de Ciências v.89 n.1 2017reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201720160407info:eu-repo/semantics/openAccessCAMASSA,JOSÉ A.DIOGO,CAMILA C.SOUSA,CRISTINA P.AZEVEDO,JORGE T.VIEGAS,CARLOS A.REIS,RUI L.DOURADO,NUNODIAS,ISABEL R.eng2017-04-11T00:00:00Zoai:scielo:S0001-37652017000100231Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2017-04-11T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false |
dc.title.none.fl_str_mv |
Bone turnover markers in sheep and goat: A review of the scientific literature |
title |
Bone turnover markers in sheep and goat: A review of the scientific literature |
spellingShingle |
Bone turnover markers in sheep and goat: A review of the scientific literature CAMASSA,JOSÉ A. Bone formation markers bone resorption markers bone metabolism small ruminants. |
title_short |
Bone turnover markers in sheep and goat: A review of the scientific literature |
title_full |
Bone turnover markers in sheep and goat: A review of the scientific literature |
title_fullStr |
Bone turnover markers in sheep and goat: A review of the scientific literature |
title_full_unstemmed |
Bone turnover markers in sheep and goat: A review of the scientific literature |
title_sort |
Bone turnover markers in sheep and goat: A review of the scientific literature |
author |
CAMASSA,JOSÉ A. |
author_facet |
CAMASSA,JOSÉ A. DIOGO,CAMILA C. SOUSA,CRISTINA P. AZEVEDO,JORGE T. VIEGAS,CARLOS A. REIS,RUI L. DOURADO,NUNO DIAS,ISABEL R. |
author_role |
author |
author2 |
DIOGO,CAMILA C. SOUSA,CRISTINA P. AZEVEDO,JORGE T. VIEGAS,CARLOS A. REIS,RUI L. DOURADO,NUNO DIAS,ISABEL R. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
CAMASSA,JOSÉ A. DIOGO,CAMILA C. SOUSA,CRISTINA P. AZEVEDO,JORGE T. VIEGAS,CARLOS A. REIS,RUI L. DOURADO,NUNO DIAS,ISABEL R. |
dc.subject.por.fl_str_mv |
Bone formation markers bone resorption markers bone metabolism small ruminants. |
topic |
Bone formation markers bone resorption markers bone metabolism small ruminants. |
description |
ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0001-3765201720160407 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
Anais da Academia Brasileira de Ciências v.89 n.1 2017 reponame:Anais da Academia Brasileira de Ciências (Online) instname:Academia Brasileira de Ciências (ABC) instacron:ABC |
instname_str |
Academia Brasileira de Ciências (ABC) |
instacron_str |
ABC |
institution |
ABC |
reponame_str |
Anais da Academia Brasileira de Ciências (Online) |
collection |
Anais da Academia Brasileira de Ciências (Online) |
repository.name.fl_str_mv |
Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC) |
repository.mail.fl_str_mv |
||aabc@abc.org.br |
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1754302864401891328 |