Bone turnover markers in sheep and goat: A review of the scientific literature

Detalhes bibliográficos
Autor(a) principal: CAMASSA,JOSÉ A.
Data de Publicação: 2017
Outros Autores: DIOGO,CAMILA C., SOUSA,CRISTINA P., AZEVEDO,JORGE T., VIEGAS,CARLOS A., REIS,RUI L., DOURADO,NUNO, DIAS,ISABEL R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231
Resumo: ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants.
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spelling Bone turnover markers in sheep and goat: A review of the scientific literatureBone formation markersbone resorption markersbone metabolismsmall ruminants.ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants.Academia Brasileira de Ciências2017-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231Anais da Academia Brasileira de Ciências v.89 n.1 2017reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201720160407info:eu-repo/semantics/openAccessCAMASSA,JOSÉ A.DIOGO,CAMILA C.SOUSA,CRISTINA P.AZEVEDO,JORGE T.VIEGAS,CARLOS A.REIS,RUI L.DOURADO,NUNODIAS,ISABEL R.eng2017-04-11T00:00:00Zoai:scielo:S0001-37652017000100231Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2017-04-11T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Bone turnover markers in sheep and goat: A review of the scientific literature
title Bone turnover markers in sheep and goat: A review of the scientific literature
spellingShingle Bone turnover markers in sheep and goat: A review of the scientific literature
CAMASSA,JOSÉ A.
Bone formation markers
bone resorption markers
bone metabolism
small ruminants.
title_short Bone turnover markers in sheep and goat: A review of the scientific literature
title_full Bone turnover markers in sheep and goat: A review of the scientific literature
title_fullStr Bone turnover markers in sheep and goat: A review of the scientific literature
title_full_unstemmed Bone turnover markers in sheep and goat: A review of the scientific literature
title_sort Bone turnover markers in sheep and goat: A review of the scientific literature
author CAMASSA,JOSÉ A.
author_facet CAMASSA,JOSÉ A.
DIOGO,CAMILA C.
SOUSA,CRISTINA P.
AZEVEDO,JORGE T.
VIEGAS,CARLOS A.
REIS,RUI L.
DOURADO,NUNO
DIAS,ISABEL R.
author_role author
author2 DIOGO,CAMILA C.
SOUSA,CRISTINA P.
AZEVEDO,JORGE T.
VIEGAS,CARLOS A.
REIS,RUI L.
DOURADO,NUNO
DIAS,ISABEL R.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv CAMASSA,JOSÉ A.
DIOGO,CAMILA C.
SOUSA,CRISTINA P.
AZEVEDO,JORGE T.
VIEGAS,CARLOS A.
REIS,RUI L.
DOURADO,NUNO
DIAS,ISABEL R.
dc.subject.por.fl_str_mv Bone formation markers
bone resorption markers
bone metabolism
small ruminants.
topic Bone formation markers
bone resorption markers
bone metabolism
small ruminants.
description ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in order to highlight the most promising BTMs in small ruminant research, as well as provide a wide view of the use of sheep and goat as animal models in orthopaedic research, type of markers and commercial assay kits with cross-reactivity in sheep and goat, method of sample and storage of serum and urine for bone turnover markers determination and the usefulness and limitations of bone turnover markers in the different studies, therefore an effective tool for researchers that seek answers to different questions while using BTMs in small ruminants.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-01
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dc.relation.none.fl_str_mv 10.1590/0001-3765201720160407
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dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.89 n.1 2017
reponame:Anais da Academia Brasileira de Ciências (Online)
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