Pathology of severe urolithiasis in a flock of egg-laying hens
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | http://hdl.handle.net/1843/67579 https://orcid.org/0000-0001-9775-1182 https://orcid.org/0000-0002-8052-5389 https://orcid.org/0000-0003-1913-7608 https://orcid.org/0000-0002-1488-6987 https://orcid.org/0000-0001-9051-1565 https://orcid.org/0000-0003-0173-3524 |
Resumo: | Fourteen, 31-week-old Lohmann white layers from a flock of 30,000 chickens had a history of apathy, and a drop in egg production. Clinical signs were observed in approximately 40% of the flock, and lasted for three months. Fourteen hens were euthanized for post-mortem examinations. Macroscopic findings included marked atrophy and loss of renal lobes along with compensatory renal hypertrophy of the contralateral lobe. Ureters were markedly dilated and filled with mucus and/or with molded white to yellow-grey uroliths that obliterated the lumen. At histopathology, the uroliths inside ureters and tubules were composed of concentrically arranged mineralized concretions, as well as urates associated with heterophilic infiltrations and epithelial hyperplasia. Renal parenchyma adjacent to obstructed ureters was compressed with tubules replaced by fibrous tissue. Multifocal interstitial lymphocytic nephritis, proteinuria and membranoproliferative glomerulonephritis were also found. Heterophilic and caseous ureteritis associated with numerous Gram-positive coccoid bacteria occurred in three chickens. Immunohistochemistry for avian coronavirus was negative. This negative result along with the case history indicated that water restriction was the most likely cause of mortality. This condition resulted in significant economic loss for this farmer. |
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2024-04-23T14:37:06Z2024-04-23T14:37:06Z202114404510.24070/bjvp.1983-0246.v14i1p40-451983-0246http://hdl.handle.net/1843/67579https://orcid.org/0000-0001-9775-1182https://orcid.org/0000-0002-8052-5389https://orcid.org/0000-0003-1913-7608https://orcid.org/0000-0002-1488-6987https://orcid.org/0000-0001-9051-1565https://orcid.org/0000-0003-0173-3524Fourteen, 31-week-old Lohmann white layers from a flock of 30,000 chickens had a history of apathy, and a drop in egg production. Clinical signs were observed in approximately 40% of the flock, and lasted for three months. Fourteen hens were euthanized for post-mortem examinations. Macroscopic findings included marked atrophy and loss of renal lobes along with compensatory renal hypertrophy of the contralateral lobe. Ureters were markedly dilated and filled with mucus and/or with molded white to yellow-grey uroliths that obliterated the lumen. At histopathology, the uroliths inside ureters and tubules were composed of concentrically arranged mineralized concretions, as well as urates associated with heterophilic infiltrations and epithelial hyperplasia. Renal parenchyma adjacent to obstructed ureters was compressed with tubules replaced by fibrous tissue. Multifocal interstitial lymphocytic nephritis, proteinuria and membranoproliferative glomerulonephritis were also found. Heterophilic and caseous ureteritis associated with numerous Gram-positive coccoid bacteria occurred in three chickens. Immunohistochemistry for avian coronavirus was negative. This negative result along with the case history indicated that water restriction was the most likely cause of mortality. This condition resulted in significant economic loss for this farmer.Quatorze poedeiras brancas Lohmann de 31 semanas de um rebanho de 30.000 galinhas tinham um histórico de apatia e uma queda na produção de ovos. Sinais clínicos foram observados em aproximadamente 40% do rebanho e duraram três meses. Quatorze galinhas foram sacrificadas para exames post-mortem. Os achados macroscópicos incluíram atrofia acentuada e perda dos lobos renais, juntamente com hipertrofia renal compensatória do lobo contralateral. Os ureteres estavam marcadamente dilatados e cheios de muco e/ou urólitos moldados de cor branca a amarelo-acinzentada que obliteravam o lúmen. Na histopatologia, os urólitos no interior dos ureteres e túbulos eram compostos por concreções mineralizadas dispostas concentricamente, além de uratos associados a infiltrações heterofílicas e hiperplasia epitelial. O parênquima renal adjacente aos ureteres obstruídos foi comprimido com túbulos substituídos por tecido fibroso. Nefrite linfocítica intersticial multifocal, proteinúria e glomerulonefrite membranoproliferativa também foram encontradas. Ureterite heterofílica e caseosa associada a numerosas bactérias cocóides Gram-positivas ocorreu em três galinhas. A imunohistoquímica para coronavírus aviário foi negativa. Este resultado negativo, juntamente com o histórico do caso, indicou que a restrição hídrica era a causa mais provável de mortalidade. Esta condição resultou em perdas econômicas significativas para este agricultor.FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorengUniversidade Federal de Minas GeraisUFMGBrasilVET - DEPARTAMENTO DE ZOOTECNIABrazilian journal of veterinary pathologyGalinhasHistopatologia veterinariaPoedeira (Galinha)RimChickensHistopathologyLayersKidneysUrolithsPathology of severe urolithiasis in a flock of egg-laying hensPatologia de urolitíase grave em um bando de galinhas poedeirasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://bjvp.org.br/v-14-n-1-7-pathology-of-severe-urolithiasis-in-a-flock-of-egg-laying-hens/Marcelo Coelho LopesRoselene EccoClarissa S. FonsecaCamila Issa AmaralLuís Henrique Gouvêa SaraivaLetícia Batelli de OliveiraDayse Helena Lages da SilvaMatheus Vilardo Lóes MoreiraFabrício J. M. da SilvaNatalie K. Armourapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/67579/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALPathology of severe urolithiasis in a flock of egg-laying hens.pdfPathology of severe urolithiasis in a flock of egg-laying hens.pdfapplication/pdf538960https://repositorio.ufmg.br/bitstream/1843/67579/2/Pathology%20of%20severe%20urolithiasis%20in%20a%20flock%20of%20egg-laying%20hens.pdf281fbc8b664d29d31beefa8bfba1c90dMD521843/675792024-04-23 11:37:07.041oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2024-04-23T14:37:07Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Pathology of severe urolithiasis in a flock of egg-laying hens |
dc.title.alternative.pt_BR.fl_str_mv |
Patologia de urolitíase grave em um bando de galinhas poedeiras |
title |
Pathology of severe urolithiasis in a flock of egg-laying hens |
spellingShingle |
Pathology of severe urolithiasis in a flock of egg-laying hens Marcelo Coelho Lopes Chickens Histopathology Layers Kidneys Uroliths Galinhas Histopatologia veterinaria Poedeira (Galinha) Rim |
title_short |
Pathology of severe urolithiasis in a flock of egg-laying hens |
title_full |
Pathology of severe urolithiasis in a flock of egg-laying hens |
title_fullStr |
Pathology of severe urolithiasis in a flock of egg-laying hens |
title_full_unstemmed |
Pathology of severe urolithiasis in a flock of egg-laying hens |
title_sort |
Pathology of severe urolithiasis in a flock of egg-laying hens |
author |
Marcelo Coelho Lopes |
author_facet |
Marcelo Coelho Lopes Roselene Ecco Clarissa S. Fonseca Camila Issa Amaral Luís Henrique Gouvêa Saraiva Letícia Batelli de Oliveira Dayse Helena Lages da Silva Matheus Vilardo Lóes Moreira Fabrício J. M. da Silva Natalie K. Armour |
author_role |
author |
author2 |
Roselene Ecco Clarissa S. Fonseca Camila Issa Amaral Luís Henrique Gouvêa Saraiva Letícia Batelli de Oliveira Dayse Helena Lages da Silva Matheus Vilardo Lóes Moreira Fabrício J. M. da Silva Natalie K. Armour |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Marcelo Coelho Lopes Roselene Ecco Clarissa S. Fonseca Camila Issa Amaral Luís Henrique Gouvêa Saraiva Letícia Batelli de Oliveira Dayse Helena Lages da Silva Matheus Vilardo Lóes Moreira Fabrício J. M. da Silva Natalie K. Armour |
dc.subject.por.fl_str_mv |
Chickens Histopathology Layers Kidneys Uroliths |
topic |
Chickens Histopathology Layers Kidneys Uroliths Galinhas Histopatologia veterinaria Poedeira (Galinha) Rim |
dc.subject.other.pt_BR.fl_str_mv |
Galinhas Histopatologia veterinaria Poedeira (Galinha) Rim |
description |
Fourteen, 31-week-old Lohmann white layers from a flock of 30,000 chickens had a history of apathy, and a drop in egg production. Clinical signs were observed in approximately 40% of the flock, and lasted for three months. Fourteen hens were euthanized for post-mortem examinations. Macroscopic findings included marked atrophy and loss of renal lobes along with compensatory renal hypertrophy of the contralateral lobe. Ureters were markedly dilated and filled with mucus and/or with molded white to yellow-grey uroliths that obliterated the lumen. At histopathology, the uroliths inside ureters and tubules were composed of concentrically arranged mineralized concretions, as well as urates associated with heterophilic infiltrations and epithelial hyperplasia. Renal parenchyma adjacent to obstructed ureters was compressed with tubules replaced by fibrous tissue. Multifocal interstitial lymphocytic nephritis, proteinuria and membranoproliferative glomerulonephritis were also found. Heterophilic and caseous ureteritis associated with numerous Gram-positive coccoid bacteria occurred in three chickens. Immunohistochemistry for avian coronavirus was negative. This negative result along with the case history indicated that water restriction was the most likely cause of mortality. This condition resulted in significant economic loss for this farmer. |
publishDate |
2021 |
dc.date.issued.fl_str_mv |
2021 |
dc.date.accessioned.fl_str_mv |
2024-04-23T14:37:06Z |
dc.date.available.fl_str_mv |
2024-04-23T14:37:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/67579 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.24070/bjvp.1983-0246.v14i1p40-45 |
dc.identifier.issn.pt_BR.fl_str_mv |
1983-0246 |
dc.identifier.orcid.pt_BR.fl_str_mv |
https://orcid.org/0000-0001-9775-1182 https://orcid.org/0000-0002-8052-5389 https://orcid.org/0000-0003-1913-7608 https://orcid.org/0000-0002-1488-6987 https://orcid.org/0000-0001-9051-1565 https://orcid.org/0000-0003-0173-3524 |
identifier_str_mv |
10.24070/bjvp.1983-0246.v14i1p40-45 1983-0246 |
url |
http://hdl.handle.net/1843/67579 https://orcid.org/0000-0001-9775-1182 https://orcid.org/0000-0002-8052-5389 https://orcid.org/0000-0003-1913-7608 https://orcid.org/0000-0002-1488-6987 https://orcid.org/0000-0001-9051-1565 https://orcid.org/0000-0003-0173-3524 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Brazilian journal of veterinary pathology |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.publisher.initials.fl_str_mv |
UFMG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
VET - DEPARTAMENTO DE ZOOTECNIA |
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Universidade Federal de Minas Gerais |
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