Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | http://dx.doi.org/10.4322/acr.2020.218 http://hdl.handle.net/1843/61358 |
Resumo: | The Numb Chin Syndrome (NCS) is defined as facial and oral numbness restricted to the mental nerve's distribution involving the lower lip, skin of the chin, or gingiva of the lower anterior teeth. Hypoesthesia can occur unilaterally or bilaterally. Although this syndrome is rare, its importance is related to the fact that it represents the clinical manifestations of malignant diseases. Breast cancer and non-Hodgkin lymphoma are the most common cause of NCS. The patient, a 58-year-old woman, treated for a Burkitt Lymphoma (BL) nine years ago, described a two-week history of change in sensitivity and pain in the chin region, without relief with the use of analgesics. She had no headache, speech disturbance, dysphagia, visual disturbance, or other neurological symptoms. No surgical intervention has been performed recently. The intraoral examination revealed a healthy oral mucosa and a small area adjacent to the right mental nerve region that was uncomfortable to palpation. No changes were found in the bone trabeculae at cone-beam computed tomography. The contrasted magnetic resonance features made it possible to identify a change in the mandibular body extending to the entire right side, coinciding with the patient's complaint, indicating a probable mandibular medullary invasion. The patient was submitted to a biopsy to rule out a possible recurrence of BL. The microscopic findings were consistent with the diagnosis of BL. The present report described a very unusual presentation of late recurrent BL nine years after the first treatment, which manifested as an NCS. |
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2023-11-24T19:21:35Z2023-11-24T19:21:35Z2021-12-0811e2020218http://dx.doi.org/10.4322/acr.2020.21822361960http://hdl.handle.net/1843/61358The Numb Chin Syndrome (NCS) is defined as facial and oral numbness restricted to the mental nerve's distribution involving the lower lip, skin of the chin, or gingiva of the lower anterior teeth. Hypoesthesia can occur unilaterally or bilaterally. Although this syndrome is rare, its importance is related to the fact that it represents the clinical manifestations of malignant diseases. Breast cancer and non-Hodgkin lymphoma are the most common cause of NCS. The patient, a 58-year-old woman, treated for a Burkitt Lymphoma (BL) nine years ago, described a two-week history of change in sensitivity and pain in the chin region, without relief with the use of analgesics. She had no headache, speech disturbance, dysphagia, visual disturbance, or other neurological symptoms. No surgical intervention has been performed recently. The intraoral examination revealed a healthy oral mucosa and a small area adjacent to the right mental nerve region that was uncomfortable to palpation. No changes were found in the bone trabeculae at cone-beam computed tomography. The contrasted magnetic resonance features made it possible to identify a change in the mandibular body extending to the entire right side, coinciding with the patient's complaint, indicating a probable mandibular medullary invasion. The patient was submitted to a biopsy to rule out a possible recurrence of BL. The microscopic findings were consistent with the diagnosis of BL. The present report described a very unusual presentation of late recurrent BL nine years after the first treatment, which manifested as an NCS.engUniversidade Federal de Minas GeraisUFMGBrasilFAO - DEPARTAMENTO DE CLÍNICAAutopsy and Case ReportsB-lymphocytesBurkitt lymphomaHypesthesiaRecurrenceLinfomanome periódico revista Autopsy and case reports open acess Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom assunto Burkitt Lymphoma busca dia 06 do 11 novembro d.c depois de Cristo segunda-feira 2023 fao clínicaLate recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptominfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.autopsyandcasereports.org/article/doi/10.4322/acr.2020.218Bernar Monteiro BenitesWanessa Miranda-SilvaAndré Caroli RochaUla Lindoso PassosFelipe Paiva FonsecaCelso Arrais Rodrigues da SilvaEduardo Rodrigues Fregnaniinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/61358/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALLate recurrence of burkitt' s lymphoma in the jaw numb chin syndrome as the only symptom.pdfLate recurrence of burkitt' s lymphoma in the jaw numb chin syndrome as the only symptom.pdfapplication/pdf1770631https://repositorio.ufmg.br/bitstream/1843/61358/2/Late%20recurrence%20of%20burkitt%27%20s%20lymphoma%20in%20the%20jaw%20%20numb%20chin%20syndrome%20as%20the%20only%20symptom.pdf871589d09fe5843e934b2b6e0e1a89c3MD521843/613582023-11-24 16:21:35.992oai:repositorio.ufmg.br:1843/61358Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-11-24T19:21:35Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
title |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
spellingShingle |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom Bernar Monteiro Benites Linfoma nome periódico revista Autopsy and case reports open acess Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom assunto Burkitt Lymphoma busca dia 06 do 11 novembro d.c depois de Cristo segunda-feira 2023 fao clínica B-lymphocytes Burkitt lymphoma Hypesthesia Recurrence |
title_short |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
title_full |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
title_fullStr |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
title_full_unstemmed |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
title_sort |
Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom |
author |
Bernar Monteiro Benites |
author_facet |
Bernar Monteiro Benites Wanessa Miranda-Silva André Caroli Rocha Ula Lindoso Passos Felipe Paiva Fonseca Celso Arrais Rodrigues da Silva Eduardo Rodrigues Fregnani |
author_role |
author |
author2 |
Wanessa Miranda-Silva André Caroli Rocha Ula Lindoso Passos Felipe Paiva Fonseca Celso Arrais Rodrigues da Silva Eduardo Rodrigues Fregnani |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bernar Monteiro Benites Wanessa Miranda-Silva André Caroli Rocha Ula Lindoso Passos Felipe Paiva Fonseca Celso Arrais Rodrigues da Silva Eduardo Rodrigues Fregnani |
dc.subject.por.fl_str_mv |
Linfoma nome periódico revista Autopsy and case reports open acess Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom assunto Burkitt Lymphoma busca dia 06 do 11 novembro d.c depois de Cristo segunda-feira 2023 fao clínica |
topic |
Linfoma nome periódico revista Autopsy and case reports open acess Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom assunto Burkitt Lymphoma busca dia 06 do 11 novembro d.c depois de Cristo segunda-feira 2023 fao clínica B-lymphocytes Burkitt lymphoma Hypesthesia Recurrence |
dc.subject.other.pt_BR.fl_str_mv |
B-lymphocytes Burkitt lymphoma Hypesthesia Recurrence |
description |
The Numb Chin Syndrome (NCS) is defined as facial and oral numbness restricted to the mental nerve's distribution involving the lower lip, skin of the chin, or gingiva of the lower anterior teeth. Hypoesthesia can occur unilaterally or bilaterally. Although this syndrome is rare, its importance is related to the fact that it represents the clinical manifestations of malignant diseases. Breast cancer and non-Hodgkin lymphoma are the most common cause of NCS. The patient, a 58-year-old woman, treated for a Burkitt Lymphoma (BL) nine years ago, described a two-week history of change in sensitivity and pain in the chin region, without relief with the use of analgesics. She had no headache, speech disturbance, dysphagia, visual disturbance, or other neurological symptoms. No surgical intervention has been performed recently. The intraoral examination revealed a healthy oral mucosa and a small area adjacent to the right mental nerve region that was uncomfortable to palpation. No changes were found in the bone trabeculae at cone-beam computed tomography. The contrasted magnetic resonance features made it possible to identify a change in the mandibular body extending to the entire right side, coinciding with the patient's complaint, indicating a probable mandibular medullary invasion. The patient was submitted to a biopsy to rule out a possible recurrence of BL. The microscopic findings were consistent with the diagnosis of BL. The present report described a very unusual presentation of late recurrent BL nine years after the first treatment, which manifested as an NCS. |
publishDate |
2021 |
dc.date.issued.fl_str_mv |
2021-12-08 |
dc.date.accessioned.fl_str_mv |
2023-11-24T19:21:35Z |
dc.date.available.fl_str_mv |
2023-11-24T19:21:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/61358 |
dc.identifier.doi.pt_BR.fl_str_mv |
http://dx.doi.org/10.4322/acr.2020.218 |
dc.identifier.issn.pt_BR.fl_str_mv |
22361960 |
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http://dx.doi.org/10.4322/acr.2020.218 http://hdl.handle.net/1843/61358 |
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22361960 |
dc.language.iso.fl_str_mv |
eng |
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Autopsy and Case Reports |
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Universidade Federal de Minas Gerais |
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UFMG |
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Brasil |
dc.publisher.department.fl_str_mv |
FAO - DEPARTAMENTO DE CLÍNICA |
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Universidade Federal de Minas Gerais |
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