Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom

• Autor(a) principal: Bernar Monteiro Benites
• Data de Publicação: 2021
• Outros Autores: Wanessa Miranda-Silva, André Caroli Rocha, Ula Lindoso Passos, Felipe Paiva Fonseca, Celso Arrais Rodrigues da Silva, Eduardo Rodrigues Fregnani
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: http://dx.doi.org/10.4322/acr.2020.218; http://hdl.handle.net/1843/61358
• topic: Linfoma; nome periódico revista Autopsy and case reports open acess Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom assunto Burkitt Lymphoma busca dia 06 do 11 novembro d.c depois de Cristo segunda-feira 2023 fao clínica; B-lymphocytes; Burkitt lymphoma; Hypesthesia; Recurrence

The Numb Chin Syndrome (NCS) is defined as facial and oral numbness restricted to the mental nerve's distribution involving the lower lip, skin of the chin, or gingiva of the lower anterior teeth. Hypoesthesia can occur unilaterally or bilaterally. Although this syndrome is rare, its importance is related to the fact that it represents the clinical manifestations of malignant diseases. Breast cancer and non-Hodgkin lymphoma are the most common cause of NCS. The patient, a 58-year-old woman, treated for a Burkitt Lymphoma (BL) nine years ago, described a two-week history of change in sensitivity and pain in the chin region, without relief with the use of analgesics. She had no headache, speech disturbance, dysphagia, visual disturbance, or other neurological symptoms. No surgical intervention has been performed recently. The intraoral examination revealed a healthy oral mucosa and a small area adjacent to the right mental nerve region that was uncomfortable to palpation. No changes were found in the bone trabeculae at cone-beam computed tomography. The contrasted magnetic resonance features made it possible to identify a change in the mandibular body extending to the entire right side, coinciding with the patient's complaint, indicating a probable mandibular medullary invasion. The patient was submitted to a biopsy to rule out a possible recurrence of BL. The microscopic findings were consistent with the diagnosis of BL. The present report described a very unusual presentation of late recurrent BL nine years after the first treatment, which manifested as an NCS.