Spatial resolution of a preclinical PET tomograph
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | http://hdl.handle.net/1843/57384 |
Resumo: | Positron emission tomography (PET) is an important molecular image modality and its application in preclinical research has increased during the last decades. Thus, in laboratory practice, it is important to implement a quality control of the equipment, since intrinsic factors influence the image quality. The objective of this work was to perform and implement spatial resolution tests for the small animal PET scanner of the Molecular Imaging Laboratory, LIM/CDTN. Empirically, the spatial resolution of a PET scanner can be determined from the measurement of point or linear sources and FWHM (full width half maximum) analysis of the PET image. In this work, a point source of 22Na and a hot rod style phantom filled with the 18F-FDG solution were used. Acquisition and reconstruction of images were performed with the LabPET 1.12.1 software, provided by the equipment manufacturer. PeakFit® and Amide software were used to perform images post-processing. The results indicate that the PET scanner spatial resolution value is compatible with values reported in an international study performed on similar equipment. |
id |
UFMG_89e49f852c16e7131d908effa1e7604a |
---|---|
oai_identifier_str |
oai:repositorio.ufmg.br:1843/57384 |
network_acronym_str |
UFMG |
network_name_str |
Repositório Institucional da UFMG |
repository_id_str |
|
spelling |
2023-08-02T20:46:52Z2023-08-02T20:46:52Z202191A011810.15392/bjrs.v9i1a.150323190612http://hdl.handle.net/1843/573840000-0001-6479-3087Positron emission tomography (PET) is an important molecular image modality and its application in preclinical research has increased during the last decades. Thus, in laboratory practice, it is important to implement a quality control of the equipment, since intrinsic factors influence the image quality. The objective of this work was to perform and implement spatial resolution tests for the small animal PET scanner of the Molecular Imaging Laboratory, LIM/CDTN. Empirically, the spatial resolution of a PET scanner can be determined from the measurement of point or linear sources and FWHM (full width half maximum) analysis of the PET image. In this work, a point source of 22Na and a hot rod style phantom filled with the 18F-FDG solution were used. Acquisition and reconstruction of images were performed with the LabPET 1.12.1 software, provided by the equipment manufacturer. PeakFit® and Amide software were used to perform images post-processing. The results indicate that the PET scanner spatial resolution value is compatible with values reported in an international study performed on similar equipment.engUniversidade Federal de Minas GeraisUFMGBrasilMEDICINA - FACULDADE DE MEDICINABrazilian Journal of Radiation SciencesTomografia por Emissão de PósitronsDiagnóstico por ImagemSPATIAL RESOLUTIONSMALL ANIMAL PET SCANNERIMAGE QUALITY CONTROLSpatial resolution of a preclinical PET tomographinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.bjrs.org.br/revista/index.php/REVISTA/article/view/1503Guilherme Cavalcante de Albuquerque SouzaRodrigo Modesto Gadelha GontijoJuliana Batista da SilvaMarcelo MamedeAndréa Vidal Ferreiraapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/57384/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALSpatial resolution of a preclinical PET tomograph pdfa.pdfSpatial resolution of a preclinical PET tomograph pdfa.pdfapplication/pdf632242https://repositorio.ufmg.br/bitstream/1843/57384/2/Spatial%20resolution%20of%20a%20preclinical%20PET%20tomograph%20pdfa.pdf1c7f7bd7515b6deb4277093a449bef81MD521843/573842023-08-02 18:11:21.637oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-08-02T21:11:21Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Spatial resolution of a preclinical PET tomograph |
title |
Spatial resolution of a preclinical PET tomograph |
spellingShingle |
Spatial resolution of a preclinical PET tomograph Guilherme Cavalcante de Albuquerque Souza SPATIAL RESOLUTION SMALL ANIMAL PET SCANNER IMAGE QUALITY CONTROL Tomografia por Emissão de Pósitrons Diagnóstico por Imagem |
title_short |
Spatial resolution of a preclinical PET tomograph |
title_full |
Spatial resolution of a preclinical PET tomograph |
title_fullStr |
Spatial resolution of a preclinical PET tomograph |
title_full_unstemmed |
Spatial resolution of a preclinical PET tomograph |
title_sort |
Spatial resolution of a preclinical PET tomograph |
author |
Guilherme Cavalcante de Albuquerque Souza |
author_facet |
Guilherme Cavalcante de Albuquerque Souza Rodrigo Modesto Gadelha Gontijo Juliana Batista da Silva Marcelo Mamede Andréa Vidal Ferreira |
author_role |
author |
author2 |
Rodrigo Modesto Gadelha Gontijo Juliana Batista da Silva Marcelo Mamede Andréa Vidal Ferreira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Guilherme Cavalcante de Albuquerque Souza Rodrigo Modesto Gadelha Gontijo Juliana Batista da Silva Marcelo Mamede Andréa Vidal Ferreira |
dc.subject.por.fl_str_mv |
SPATIAL RESOLUTION SMALL ANIMAL PET SCANNER IMAGE QUALITY CONTROL |
topic |
SPATIAL RESOLUTION SMALL ANIMAL PET SCANNER IMAGE QUALITY CONTROL Tomografia por Emissão de Pósitrons Diagnóstico por Imagem |
dc.subject.other.pt_BR.fl_str_mv |
Tomografia por Emissão de Pósitrons Diagnóstico por Imagem |
description |
Positron emission tomography (PET) is an important molecular image modality and its application in preclinical research has increased during the last decades. Thus, in laboratory practice, it is important to implement a quality control of the equipment, since intrinsic factors influence the image quality. The objective of this work was to perform and implement spatial resolution tests for the small animal PET scanner of the Molecular Imaging Laboratory, LIM/CDTN. Empirically, the spatial resolution of a PET scanner can be determined from the measurement of point or linear sources and FWHM (full width half maximum) analysis of the PET image. In this work, a point source of 22Na and a hot rod style phantom filled with the 18F-FDG solution were used. Acquisition and reconstruction of images were performed with the LabPET 1.12.1 software, provided by the equipment manufacturer. PeakFit® and Amide software were used to perform images post-processing. The results indicate that the PET scanner spatial resolution value is compatible with values reported in an international study performed on similar equipment. |
publishDate |
2021 |
dc.date.issued.fl_str_mv |
2021 |
dc.date.accessioned.fl_str_mv |
2023-08-02T20:46:52Z |
dc.date.available.fl_str_mv |
2023-08-02T20:46:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/57384 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.15392/bjrs.v9i1a.1503 |
dc.identifier.issn.pt_BR.fl_str_mv |
23190612 |
dc.identifier.orcid.pt_BR.fl_str_mv |
0000-0001-6479-3087 |
identifier_str_mv |
10.15392/bjrs.v9i1a.1503 23190612 0000-0001-6479-3087 |
url |
http://hdl.handle.net/1843/57384 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Brazilian Journal of Radiation Sciences |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.publisher.initials.fl_str_mv |
UFMG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
MEDICINA - FACULDADE DE MEDICINA |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Repositório Institucional da UFMG |
collection |
Repositório Institucional da UFMG |
bitstream.url.fl_str_mv |
https://repositorio.ufmg.br/bitstream/1843/57384/1/License.txt https://repositorio.ufmg.br/bitstream/1843/57384/2/Spatial%20resolution%20of%20a%20preclinical%20PET%20tomograph%20pdfa.pdf |
bitstream.checksum.fl_str_mv |
fa505098d172de0bc8864fc1287ffe22 1c7f7bd7515b6deb4277093a449bef81 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
|
_version_ |
1803589575942078464 |