Spatial resolution of a preclinical PET tomograph

• Autor(a) principal: Guilherme Cavalcante de Albuquerque Souza
• Data de Publicação: 2021
• Outros Autores: Rodrigo Modesto Gadelha Gontijo, Juliana Batista da Silva, Marcelo Mamede, Andréa Vidal Ferreira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: http://hdl.handle.net/1843/57384
• topic: SPATIAL RESOLUTION; SMALL ANIMAL PET SCANNER; IMAGE QUALITY CONTROL; Tomografia por Emissão de Pósitrons; Diagnóstico por Imagem

Positron emission tomography (PET) is an important molecular image modality and its application in preclinical research has increased during the last decades. Thus, in laboratory practice, it is important to implement a quality control of the equipment, since intrinsic factors influence the image quality. The objective of this work was to perform and implement spatial resolution tests for the small animal PET scanner of the Molecular Imaging Laboratory, LIM/CDTN. Empirically, the spatial resolution of a PET scanner can be determined from the measurement of point or linear sources and FWHM (full width half maximum) analysis of the PET image. In this work, a point source of 22Na and a hot rod style phantom filled with the 18F-FDG solution were used. Acquisition and reconstruction of images were performed with the LabPET 1.12.1 software, provided by the equipment manufacturer. PeakFit® and Amide software were used to perform images post-processing. The results indicate that the PET scanner spatial resolution value is compatible with values reported in an international study performed on similar equipment.