Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.3390/nu10080981 http://hdl.handle.net/1843/60056 https://orcid.org/0000-0003-0116-7411 https://orcid.org/0000-0002-0987-368X https://orcid.org/0000-0001-8349-5042 https://orcid.org/0000-0002-4477-5241 https://orcid.org/0000-0001-7383-7811 https://orcid.org/0000-0001-6889-7334 https://orcid.org/0000-0001-8746-5860 |
Resumo: | The secular trend of hyperuricemia coincides with the substantial increase in the consumption of sugar-sweetened beverages. Our aim was to evaluate the association between the consumption of soft drinks, dietary fructose and unsweetened, non-processed fruit juices with hyperuricemia in a cross-sectional analysis of baseline data (2008–2010; n = 7173) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The explanatory variables were the consumption of soft drinks, fruit juice, and fructose using a validated semi-quantitative food frequency questionnaire. The outcomes were hyperuricemia and the uric acid concentration in serum. Regression models were tested, and a significance level of 5% was adopted. In men, the daily consumption of a portion of soft drink/day (250 mL) almost doubled the chance of hyperuricemia with a linear trend. In women, the consumption of _0.1 to <1.0 soft drink/day was associated with a higher chance of hyperuricemia, but there was no linear trend. High fructose consumption in men and moderate and high consumption in women were associated with hyperuricemia. All categories of soft drinks consumption were linearly associated with increased serum uric acid levels. Our findings suggest that the consumption of soft drinks and dietary fructose is positively associated with a higher chance of hyperuricemia and higher uric acid levels in Brazilian adults. |
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2023-10-25T20:37:57Z2023-10-25T20:37:57Z2018-07-27108https://doi.org/10.3390/nu100809812072-6643http://hdl.handle.net/1843/60056https://orcid.org/0000-0003-0116-7411https://orcid.org/0000-0002-0987-368Xhttps://orcid.org/0000-0001-8349-5042https://orcid.org/0000-0002-4477-5241https://orcid.org/0000-0001-7383-7811https://orcid.org/0000-0001-6889-7334https://orcid.org/0000-0001-8746-5860The secular trend of hyperuricemia coincides with the substantial increase in the consumption of sugar-sweetened beverages. Our aim was to evaluate the association between the consumption of soft drinks, dietary fructose and unsweetened, non-processed fruit juices with hyperuricemia in a cross-sectional analysis of baseline data (2008–2010; n = 7173) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The explanatory variables were the consumption of soft drinks, fruit juice, and fructose using a validated semi-quantitative food frequency questionnaire. The outcomes were hyperuricemia and the uric acid concentration in serum. Regression models were tested, and a significance level of 5% was adopted. In men, the daily consumption of a portion of soft drink/day (250 mL) almost doubled the chance of hyperuricemia with a linear trend. In women, the consumption of _0.1 to <1.0 soft drink/day was associated with a higher chance of hyperuricemia, but there was no linear trend. High fructose consumption in men and moderate and high consumption in women were associated with hyperuricemia. All categories of soft drinks consumption were linearly associated with increased serum uric acid levels. Our findings suggest that the consumption of soft drinks and dietary fructose is positively associated with a higher chance of hyperuricemia and higher uric acid levels in Brazilian adults.A tendência secular da hiperuricemia coincide com o aumento substancial do consumo de bebidas açucaradas. Nosso objetivo foi avaliar a associação entre o consumo de refrigerantes, frutose dietética e sucos de frutas não processados e sem açúcar com hiperuricemia em uma análise transversal de dados de base (2008–2010; n = 7.173) do Estudo Longitudinal Brasileiro de Saúde do Adulto (ELSA-Brasil). As variáveis explicativas foram o consumo de refrigerantes, suco de frutas e frutose por meio de questionário de frequência alimentar semiquantitativo validado. Os desfechos foram hiperuricemia e concentração de ácido úrico no soro. Foram testados modelos de regressão e adotado nível de significância de 5%. Nos homens, o consumo diário de uma porção de refrigerante/dia (250 mL) quase dobrou a chance de hiperuricemia com tendência linear. Nas mulheres, o consumo de _0,1 a <1,0 refrigerante/dia foi associado a maior chance de hiperuricemia, mas não houve tendência linear. O alto consumo de frutose em homens e o consumo moderado e alto em mulheres foram associados à hiperuricemia. Todas as categorias de consumo de refrigerantes foram linearmente associadas ao aumento dos níveis séricos de ácido úrico. Nossos achados sugerem que o consumo de refrigerantes e frutose na dieta está positivamente associado a maior chance de hiperuricemia e níveis mais elevados de ácido úrico em adultos brasileiros.CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e ProjetosengUniversidade Federal de Minas GeraisUFMGBrasilENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICAMED - DEPARTAMENTO DE CLÍNICA MÉDICAMED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIALNutrientsBebidas adoçadas com açúcarSucos de frutas e vegetaisFrutoseÁcido úricoHiperuricemiaSugar-sweetened soft drinks intakeFruit and vegetable juicesFructoseUric acidHyperuricemiaSugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil)O consumo de refrigerantes adoçados com açúcar e frutose associado à hiperuricemia: análise transversal do Brasil, Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.mdpi.com/2072-6643/10/8/981Jordana Herzog SiqueiraJosé Geraldo MillGustavo Velasquez-MelendezAlexandra Dias MoreiraSandhi Maria BarretoIsabela Martins BenseñorMaria del Carmen Bisi Molinaapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGORIGINALSweetened soft drinks consumption is associated with metabolic syndrome cross-sectional analysis from the brazilian longitudinal study of adult healt_PDF-A.pdfSweetened soft drinks consumption is associated with metabolic syndrome cross-sectional analysis from the brazilian longitudinal study of adult healt_PDF-A.pdfapplication/pdf237318https://repositorio.ufmg.br/bitstream/1843/60056/2/Sweetened%20soft%20drinks%20consumption%20is%20associated%20with%20metabolic%20syndrome%20cross-sectional%20analysis%20from%20the%20brazilian%20longitudinal%20study%20of%20adult%20healt_PDF-A.pdfb38fce9902516b6916b76666eb7ef5a9MD52LICENSELicense.txtLicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
dc.title.alternative.pt_BR.fl_str_mv |
O consumo de refrigerantes adoçados com açúcar e frutose associado à hiperuricemia: análise transversal do Brasil, Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) |
title |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
spellingShingle |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) Jordana Herzog Siqueira Sugar-sweetened soft drinks intake Fruit and vegetable juices Fructose Uric acid Hyperuricemia Bebidas adoçadas com açúcar Sucos de frutas e vegetais Frutose Ácido úrico Hiperuricemia |
title_short |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
title_full |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
title_fullStr |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
title_full_unstemmed |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
title_sort |
Sugar-sweetened soft drinks and fructose consumption are associated with hyperuricemia: cross-sectional analysis from the brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
author |
Jordana Herzog Siqueira |
author_facet |
Jordana Herzog Siqueira José Geraldo Mill Gustavo Velasquez-Melendez Alexandra Dias Moreira Sandhi Maria Barreto Isabela Martins Benseñor Maria del Carmen Bisi Molina |
author_role |
author |
author2 |
José Geraldo Mill Gustavo Velasquez-Melendez Alexandra Dias Moreira Sandhi Maria Barreto Isabela Martins Benseñor Maria del Carmen Bisi Molina |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Jordana Herzog Siqueira José Geraldo Mill Gustavo Velasquez-Melendez Alexandra Dias Moreira Sandhi Maria Barreto Isabela Martins Benseñor Maria del Carmen Bisi Molina |
dc.subject.por.fl_str_mv |
Sugar-sweetened soft drinks intake Fruit and vegetable juices Fructose Uric acid Hyperuricemia |
topic |
Sugar-sweetened soft drinks intake Fruit and vegetable juices Fructose Uric acid Hyperuricemia Bebidas adoçadas com açúcar Sucos de frutas e vegetais Frutose Ácido úrico Hiperuricemia |
dc.subject.other.pt_BR.fl_str_mv |
Bebidas adoçadas com açúcar Sucos de frutas e vegetais Frutose Ácido úrico Hiperuricemia |
description |
The secular trend of hyperuricemia coincides with the substantial increase in the consumption of sugar-sweetened beverages. Our aim was to evaluate the association between the consumption of soft drinks, dietary fructose and unsweetened, non-processed fruit juices with hyperuricemia in a cross-sectional analysis of baseline data (2008–2010; n = 7173) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The explanatory variables were the consumption of soft drinks, fruit juice, and fructose using a validated semi-quantitative food frequency questionnaire. The outcomes were hyperuricemia and the uric acid concentration in serum. Regression models were tested, and a significance level of 5% was adopted. In men, the daily consumption of a portion of soft drink/day (250 mL) almost doubled the chance of hyperuricemia with a linear trend. In women, the consumption of _0.1 to <1.0 soft drink/day was associated with a higher chance of hyperuricemia, but there was no linear trend. High fructose consumption in men and moderate and high consumption in women were associated with hyperuricemia. All categories of soft drinks consumption were linearly associated with increased serum uric acid levels. Our findings suggest that the consumption of soft drinks and dietary fructose is positively associated with a higher chance of hyperuricemia and higher uric acid levels in Brazilian adults. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-07-27 |
dc.date.accessioned.fl_str_mv |
2023-10-25T20:37:57Z |
dc.date.available.fl_str_mv |
2023-10-25T20:37:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/60056 |
dc.identifier.doi.pt_BR.fl_str_mv |
https://doi.org/10.3390/nu10080981 |
dc.identifier.issn.pt_BR.fl_str_mv |
2072-6643 |
dc.identifier.orcid.pt_BR.fl_str_mv |
https://orcid.org/0000-0003-0116-7411 https://orcid.org/0000-0002-0987-368X https://orcid.org/0000-0001-8349-5042 https://orcid.org/0000-0002-4477-5241 https://orcid.org/0000-0001-7383-7811 https://orcid.org/0000-0001-6889-7334 https://orcid.org/0000-0001-8746-5860 |
url |
https://doi.org/10.3390/nu10080981 http://hdl.handle.net/1843/60056 https://orcid.org/0000-0003-0116-7411 https://orcid.org/0000-0002-0987-368X https://orcid.org/0000-0001-8349-5042 https://orcid.org/0000-0002-4477-5241 https://orcid.org/0000-0001-7383-7811 https://orcid.org/0000-0001-6889-7334 https://orcid.org/0000-0001-8746-5860 |
identifier_str_mv |
2072-6643 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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Nutrients |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
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UFMG |
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Brasil |
dc.publisher.department.fl_str_mv |
ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA MED - DEPARTAMENTO DE CLÍNICA MÉDICA MED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIAL |
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Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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