Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications

Detalhes bibliográficos
Autor(a) principal: Daisy Motta Santos
Data de Publicação: 2020
Outros Autores: Robson Augusto Souza dos Santos, Sérgio Henrique Sousa Santos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1002/oby.22949
http://hdl.handle.net/1843/45004
Resumo: We have read with interest the recent review by Zbinden-Foncea et al. suggesting that high levels of cardiorespiratory fitness induced by prior exercise training may confer some innate immune protection against coronavirus disease (COVID-19) by attenuating the “cytokine storm syndrome” by modulating angiotensin-converting enzyme 2 (ACE2) effects. However, it is important to highlight that the benefic effects of physical exercise also involves the angiotensin-(1-7)/MAS1 proto-oncogene, GPCR receptor (MAS receptor; Mas) axis activation.
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spelling Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implicationsObesidadeAngiotensinaCOVID-19 (Doença)Exercícios físicosWe have read with interest the recent review by Zbinden-Foncea et al. suggesting that high levels of cardiorespiratory fitness induced by prior exercise training may confer some innate immune protection against coronavirus disease (COVID-19) by attenuating the “cytokine storm syndrome” by modulating angiotensin-converting enzyme 2 (ACE2) effects. However, it is important to highlight that the benefic effects of physical exercise also involves the angiotensin-(1-7)/MAS1 proto-oncogene, GPCR receptor (MAS receptor; Mas) axis activation.CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorUniversidade Federal de Minas GeraisBrasilICA - INSTITUTO DE CIÊNCIAS AGRÁRIASUFMG2022-09-08T15:16:01Z2022-09-08T15:16:01Z2020-06-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.1002/oby.229491930-739Xhttp://hdl.handle.net/1843/45004engObesityDaisy Motta SantosRobson Augusto Souza dos SantosSérgio Henrique Sousa Santosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2022-09-08T15:16:02Zoai:repositorio.ufmg.br:1843/45004Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2022-09-08T15:16:02Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
title Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
spellingShingle Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
Daisy Motta Santos
Obesidade
Angiotensina
COVID-19 (Doença)
Exercícios físicos
title_short Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
title_full Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
title_fullStr Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
title_full_unstemmed Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
title_sort Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
author Daisy Motta Santos
author_facet Daisy Motta Santos
Robson Augusto Souza dos Santos
Sérgio Henrique Sousa Santos
author_role author
author2 Robson Augusto Souza dos Santos
Sérgio Henrique Sousa Santos
author2_role author
author
dc.contributor.author.fl_str_mv Daisy Motta Santos
Robson Augusto Souza dos Santos
Sérgio Henrique Sousa Santos
dc.subject.por.fl_str_mv Obesidade
Angiotensina
COVID-19 (Doença)
Exercícios físicos
topic Obesidade
Angiotensina
COVID-19 (Doença)
Exercícios físicos
description We have read with interest the recent review by Zbinden-Foncea et al. suggesting that high levels of cardiorespiratory fitness induced by prior exercise training may confer some innate immune protection against coronavirus disease (COVID-19) by attenuating the “cytokine storm syndrome” by modulating angiotensin-converting enzyme 2 (ACE2) effects. However, it is important to highlight that the benefic effects of physical exercise also involves the angiotensin-(1-7)/MAS1 proto-oncogene, GPCR receptor (MAS receptor; Mas) axis activation.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-04
2022-09-08T15:16:01Z
2022-09-08T15:16:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.1002/oby.22949
1930-739X
http://hdl.handle.net/1843/45004
url https://doi.org/10.1002/oby.22949
http://hdl.handle.net/1843/45004
identifier_str_mv 1930-739X
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Obesity
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
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