Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.

Detalhes bibliográficos
Autor(a) principal: Butera, Anna Paola
Data de Publicação: 2007
Outros Autores: Souza Filho, José Dias de, Carvalho, Diogo Teixeira, Figueiredo, Rute Cunha, Faria, Luiz Carlos Alves de, Nunes, Maria Angélica Antunes, Prado, Maria Auxiliadora Fontes, Alves, Ricardo José, Andrade, Milton Hércules Guerra de, Rúbio, Karina Taciana Santos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFOP
Texto Completo: http://www.repositorio.ufop.br/handle/123456789/4558
http://dx.doi.org/10.1590/S0100-40422007000500040
Resumo: We report herein the synthesis of some -D-galactopyranosylamine and -lactosylamine amides and sulfonamides. The interactions of these compounds with lectins from the seeds of Erythrina cristagalli (LEC) and Ricinus communis (RCA120) were evaluated in a hemagglutination inhibitory activity assay. D-Galactose and lactose were used as reference compounds. The -lactosylamine amides and sulfonamides were nearly as active as lactose in inhibiting LEC mediated hemagglutination and were less active against RCA120 agglutinin. The -D-galactopyranosylamine amides and sulfonamides were, with one exception, considerably less active than Dgalactose in the assay with both lectins.
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spelling Butera, Anna PaolaSouza Filho, José Dias deCarvalho, Diogo TeixeiraFigueiredo, Rute CunhaFaria, Luiz Carlos Alves deNunes, Maria Angélica AntunesPrado, Maria Auxiliadora FontesAlves, Ricardo JoséAndrade, Milton Hércules Guerra deRúbio, Karina Taciana Santos2015-03-06T18:37:21Z2015-03-06T18:37:21Z2007BUTERA. A. P. et al. Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis. Química Nova, v. 1, p. 1-5, 2007. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500040&lang=pt>. Acesso em: 08 nov. 2014.1678-7064http://www.repositorio.ufop.br/handle/123456789/4558http://dx.doi.org/10.1590/S0100-40422007000500040We report herein the synthesis of some -D-galactopyranosylamine and -lactosylamine amides and sulfonamides. The interactions of these compounds with lectins from the seeds of Erythrina cristagalli (LEC) and Ricinus communis (RCA120) were evaluated in a hemagglutination inhibitory activity assay. D-Galactose and lactose were used as reference compounds. The -lactosylamine amides and sulfonamides were nearly as active as lactose in inhibiting LEC mediated hemagglutination and were less active against RCA120 agglutinin. The -D-galactopyranosylamine amides and sulfonamides were, with one exception, considerably less active than Dgalactose in the assay with both lectins.CarbohydratesPlant lectinsAmidesSíntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.Synthesis of amides and sulfonamides of d-galactopyranosylamine and lactosylamine and evaluation of their interactions with the lectins from erythrina cristagalli and ricinus communis.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleA Sociedade Brasileira de Química dá permissão à UFOP para reproduzir no RI/UFOP, uma cópia em formato eletrônico dos artigos completos, sem nenhuma edição e/ou modificação, publicados na revista Química Nova, que tenham como autores seus alunos e/ou professores. Fonte: Email do editor de 17 set. 2013.info:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOPLICENSElicense.txtlicense.txttext/plain; charset=utf-82636http://www.repositorio.ufop.br/bitstream/123456789/4558/2/license.txtc2ffdd99e58acf69202dff00d361f23aMD52ORIGINALARTIGO_SinteseAmidasSulfonamidas.pdfARTIGO_SinteseAmidasSulfonamidas.pdfapplication/pdf241346http://www.repositorio.ufop.br/bitstream/123456789/4558/1/ARTIGO_SinteseAmidasSulfonamidas.pdf88d003aab87c8ed6790bda19ce3aa291MD51123456789/45582019-07-16 09:01:58.374oai:localhost: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Repositório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332019-07-16T13:01:58Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false
dc.title.pt_BR.fl_str_mv Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
dc.title.alternative.pt_BR.fl_str_mv Synthesis of amides and sulfonamides of d-galactopyranosylamine and lactosylamine and evaluation of their interactions with the lectins from erythrina cristagalli and ricinus communis.
title Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
spellingShingle Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
Butera, Anna Paola
Carbohydrates
Plant lectins
Amides
title_short Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
title_full Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
title_fullStr Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
title_full_unstemmed Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
title_sort Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis.
author Butera, Anna Paola
author_facet Butera, Anna Paola
Souza Filho, José Dias de
Carvalho, Diogo Teixeira
Figueiredo, Rute Cunha
Faria, Luiz Carlos Alves de
Nunes, Maria Angélica Antunes
Prado, Maria Auxiliadora Fontes
Alves, Ricardo José
Andrade, Milton Hércules Guerra de
Rúbio, Karina Taciana Santos
author_role author
author2 Souza Filho, José Dias de
Carvalho, Diogo Teixeira
Figueiredo, Rute Cunha
Faria, Luiz Carlos Alves de
Nunes, Maria Angélica Antunes
Prado, Maria Auxiliadora Fontes
Alves, Ricardo José
Andrade, Milton Hércules Guerra de
Rúbio, Karina Taciana Santos
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Butera, Anna Paola
Souza Filho, José Dias de
Carvalho, Diogo Teixeira
Figueiredo, Rute Cunha
Faria, Luiz Carlos Alves de
Nunes, Maria Angélica Antunes
Prado, Maria Auxiliadora Fontes
Alves, Ricardo José
Andrade, Milton Hércules Guerra de
Rúbio, Karina Taciana Santos
dc.subject.por.fl_str_mv Carbohydrates
Plant lectins
Amides
topic Carbohydrates
Plant lectins
Amides
description We report herein the synthesis of some -D-galactopyranosylamine and -lactosylamine amides and sulfonamides. The interactions of these compounds with lectins from the seeds of Erythrina cristagalli (LEC) and Ricinus communis (RCA120) were evaluated in a hemagglutination inhibitory activity assay. D-Galactose and lactose were used as reference compounds. The -lactosylamine amides and sulfonamides were nearly as active as lactose in inhibiting LEC mediated hemagglutination and were less active against RCA120 agglutinin. The -D-galactopyranosylamine amides and sulfonamides were, with one exception, considerably less active than Dgalactose in the assay with both lectins.
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2015-03-06T18:37:21Z
dc.date.available.fl_str_mv 2015-03-06T18:37:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv BUTERA. A. P. et al. Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis. Química Nova, v. 1, p. 1-5, 2007. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500040&lang=pt>. Acesso em: 08 nov. 2014.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufop.br/handle/123456789/4558
dc.identifier.issn.none.fl_str_mv 1678-7064
dc.identifier.doi.none.fl_str_mv http://dx.doi.org/10.1590/S0100-40422007000500040
identifier_str_mv BUTERA. A. P. et al. Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e avaliação de suas interações com lectinas de erythrina cristagalli e de ricinus communis. Química Nova, v. 1, p. 1-5, 2007. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500040&lang=pt>. Acesso em: 08 nov. 2014.
1678-7064
url http://www.repositorio.ufop.br/handle/123456789/4558
http://dx.doi.org/10.1590/S0100-40422007000500040
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collection Repositório Institucional da UFOP
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