Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum

Detalhes bibliográficos
Autor(a) principal: PINHEIRO, Eduardo Antonio Abreu
Data de Publicação: 2016
Outros Autores: BORGES, Fábio Cardoso, PINA, Jeferson Rodrigo Souza, FERREIRA, Leila do Remédio Santos, CORDEIRO, Jorgeffson da Silva, CARVALHO, Josiwander Miranda, FEITOSA, André de Oliveira, CAMPOS, Francinete Ramos, BARISON, Andersson, SOUZA, Afonso Duarte Leão de, MARINHO, Patrícia Santana Barbosa, MARINHO, Andrey Moacir do Rosário
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFPA
Texto Completo: http://repositorio.ufpa.br/jspui/handle/2011/8880
Resumo: The paper describes the isolation of ergosterol peroxide, monocerin, annularin I and annularin J compounds of Exserohilum rostratum biomass extracts. Compounds were isolated by silica gel column chromatography in polarity gradient and the structures were determined by nuclear magnetic resonance (NMR) and mass spectrometry (MS) methods. Monocerin, annularin I and annularin J compounds were tested against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis bacteria and showed moderate activity. Annularin I and annularin J compounds are new natural products.
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spelling 2017-07-19T18:19:10Z2017-07-19T18:19:10Z2016-08PINHEIRO, Eduardo Antonio Abreu et al. Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum. Journal of the Brazilian Chemical Society, São Paulo, v. 27, n. 8, p. 1432-1436, ago. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801432&lng=pt&nrm=iso>. Acesso em: 19 jul. 2017. <http://dx.doi.org/10.5935/0103-5053.20160140>.1678-4790http://repositorio.ufpa.br/jspui/handle/2011/8880The paper describes the isolation of ergosterol peroxide, monocerin, annularin I and annularin J compounds of Exserohilum rostratum biomass extracts. Compounds were isolated by silica gel column chromatography in polarity gradient and the structures were determined by nuclear magnetic resonance (NMR) and mass spectrometry (MS) methods. Monocerin, annularin I and annularin J compounds were tested against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis bacteria and showed moderate activity. Annularin I and annularin J compounds are new natural products.porUniversidade Federal do ParáUFPABrasilJournal of the Brazilian Chemical SocietyFungo endofíticoAnnularinsMicroorganismosFungo exserohilum rostratumTeste antimicrobianoAnnularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratuminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article27814321436PINHEIRO, Eduardo Antonio AbreuBORGES, Fábio CardosoPINA, Jeferson Rodrigo SouzaFERREIRA, Leila do Remédio SantosCORDEIRO, Jorgeffson da SilvaCARVALHO, Josiwander MirandaFEITOSA, André de OliveiraCAMPOS, Francinete RamosBARISON, AnderssonSOUZA, Afonso Duarte Leão deMARINHO, Patrícia Santana BarbosaMARINHO, Andrey Moacir do Rosárioinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPACC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/8880/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/8880/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/8880/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54ORIGINALArtigo_AnnularinsNewMetabolites.pdfArtigo_AnnularinsNewMetabolites.pdfapplication/pdf147410http://repositorio.ufpa.br/oai/bitstream/2011/8880/1/Artigo_AnnularinsNewMetabolites.pdfd6098398ea37cbbac8954bbd8b2471e6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81866http://repositorio.ufpa.br/oai/bitstream/2011/8880/5/license.txt43cd690d6a359e86c1fe3d5b7cba0c9bMD55TEXTArtigo_AnnularinsNewMetabolites.pdf.txtArtigo_AnnularinsNewMetabolites.pdf.txtExtracted texttext/plain17642http://repositorio.ufpa.br/oai/bitstream/2011/8880/6/Artigo_AnnularinsNewMetabolites.pdf.txt56bd4ad52d129146596fbdc8a80ae59fMD562011/88802017-12-20 12:30:47.646oai:repositorio.ufpa.br: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ório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232017-12-20T15:30:47Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false
dc.title.pt_BR.fl_str_mv Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
title Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
spellingShingle Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
PINHEIRO, Eduardo Antonio Abreu
Fungo endofítico
Annularins
Microorganismos
Fungo exserohilum rostratum
Teste antimicrobiano
title_short Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
title_full Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
title_fullStr Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
title_full_unstemmed Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
title_sort Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
author PINHEIRO, Eduardo Antonio Abreu
author_facet PINHEIRO, Eduardo Antonio Abreu
BORGES, Fábio Cardoso
PINA, Jeferson Rodrigo Souza
FERREIRA, Leila do Remédio Santos
CORDEIRO, Jorgeffson da Silva
CARVALHO, Josiwander Miranda
FEITOSA, André de Oliveira
CAMPOS, Francinete Ramos
BARISON, Andersson
SOUZA, Afonso Duarte Leão de
MARINHO, Patrícia Santana Barbosa
MARINHO, Andrey Moacir do Rosário
author_role author
author2 BORGES, Fábio Cardoso
PINA, Jeferson Rodrigo Souza
FERREIRA, Leila do Remédio Santos
CORDEIRO, Jorgeffson da Silva
CARVALHO, Josiwander Miranda
FEITOSA, André de Oliveira
CAMPOS, Francinete Ramos
BARISON, Andersson
SOUZA, Afonso Duarte Leão de
MARINHO, Patrícia Santana Barbosa
MARINHO, Andrey Moacir do Rosário
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv PINHEIRO, Eduardo Antonio Abreu
BORGES, Fábio Cardoso
PINA, Jeferson Rodrigo Souza
FERREIRA, Leila do Remédio Santos
CORDEIRO, Jorgeffson da Silva
CARVALHO, Josiwander Miranda
FEITOSA, André de Oliveira
CAMPOS, Francinete Ramos
BARISON, Andersson
SOUZA, Afonso Duarte Leão de
MARINHO, Patrícia Santana Barbosa
MARINHO, Andrey Moacir do Rosário
dc.subject.por.fl_str_mv Fungo endofítico
Annularins
Microorganismos
Fungo exserohilum rostratum
Teste antimicrobiano
topic Fungo endofítico
Annularins
Microorganismos
Fungo exserohilum rostratum
Teste antimicrobiano
description The paper describes the isolation of ergosterol peroxide, monocerin, annularin I and annularin J compounds of Exserohilum rostratum biomass extracts. Compounds were isolated by silica gel column chromatography in polarity gradient and the structures were determined by nuclear magnetic resonance (NMR) and mass spectrometry (MS) methods. Monocerin, annularin I and annularin J compounds were tested against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis bacteria and showed moderate activity. Annularin I and annularin J compounds are new natural products.
publishDate 2016
dc.date.issued.fl_str_mv 2016-08
dc.date.accessioned.fl_str_mv 2017-07-19T18:19:10Z
dc.date.available.fl_str_mv 2017-07-19T18:19:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv PINHEIRO, Eduardo Antonio Abreu et al. Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum. Journal of the Brazilian Chemical Society, São Paulo, v. 27, n. 8, p. 1432-1436, ago. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801432&lng=pt&nrm=iso>. Acesso em: 19 jul. 2017. <http://dx.doi.org/10.5935/0103-5053.20160140>.
dc.identifier.uri.fl_str_mv http://repositorio.ufpa.br/jspui/handle/2011/8880
dc.identifier.issn.pt_BR.fl_str_mv 1678-4790
identifier_str_mv PINHEIRO, Eduardo Antonio Abreu et al. Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum. Journal of the Brazilian Chemical Society, São Paulo, v. 27, n. 8, p. 1432-1436, ago. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000801432&lng=pt&nrm=iso>. Acesso em: 19 jul. 2017. <http://dx.doi.org/10.5935/0103-5053.20160140>.
1678-4790
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dc.relation.ispartof.pt_BR.fl_str_mv Journal of the Brazilian Chemical Society
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