Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/125264 |
Resumo: | OBJECTIVE: Total lung capacity (TLC) can be measured using body plethysmography,single-breath helium or RX planimetry. Body plethysmography is the goldstandard test,allowing comparison with other methods. The single breath helium method (SBHe),when used in association with CO2diffusing capacity, can estimate lung volumes inpatients with airway flow obstruction. The aim of the present study is to evaluate if TLCmeasured with SBHe after treatment with bronchodilator is similar to that obtained frombody plethysmography.MATERIALS AND METHODS: The sample included 155 adult patients submitted topulmonary function testing including lung volumes at the Pulmonary Physiology Unit,Pulmonary Department at Hospital de Clínicas de Porto Alegre. The patients were placedin two groups: one group underwent SBHe with bronchodilator, and the other group wassubmitted to SBHe without bronchodilator. Afterwards, each group was subdivided intotwo subgroups: normal patients and patients with airway obstruction.RESULTS: The TLC results obtained with the body plethysmography technique weregreater than the alternative methods for all groups. In the group without bronchodilatortreatment, there was a median difference of 934 ml (CI 95% = 657 ml – 1210 ml;P<0.001) for normal patients, and a median difference of 1679 ml (95% Cl = 1289ml –2069 ml; P<0.001) for patients with airway obstruction. While bronchodilator treatmentwas used, the median difference for normal patients with airway obstruction was 1751ml (95% Cl 1516 – 1985 ml; P<0.001).CONCLUSIONS: The results showed that treatment with bronchodilator did not makeTLC measurements similar when SBHe was compared to body plethysmography, neitherfor normal patients nor for patients with airway obstruction; this leads to the conclusionthat SBHe is not a reliable test for TLC measurements. |
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Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilatorDeterminação da capacidade pulmonar total: pletismografia versus método de diluição do hélio em respiração única após teste broncodilatadorTestes de função pulmonarvolumes pulmonaresdistúrbio ventilatório obstrutivoPulmonary function testslung volumeairflow obstructive defectOBJECTIVE: Total lung capacity (TLC) can be measured using body plethysmography,single-breath helium or RX planimetry. Body plethysmography is the goldstandard test,allowing comparison with other methods. The single breath helium method (SBHe),when used in association with CO2diffusing capacity, can estimate lung volumes inpatients with airway flow obstruction. The aim of the present study is to evaluate if TLCmeasured with SBHe after treatment with bronchodilator is similar to that obtained frombody plethysmography.MATERIALS AND METHODS: The sample included 155 adult patients submitted topulmonary function testing including lung volumes at the Pulmonary Physiology Unit,Pulmonary Department at Hospital de Clínicas de Porto Alegre. The patients were placedin two groups: one group underwent SBHe with bronchodilator, and the other group wassubmitted to SBHe without bronchodilator. Afterwards, each group was subdivided intotwo subgroups: normal patients and patients with airway obstruction.RESULTS: The TLC results obtained with the body plethysmography technique weregreater than the alternative methods for all groups. In the group without bronchodilatortreatment, there was a median difference of 934 ml (CI 95% = 657 ml – 1210 ml;P<0.001) for normal patients, and a median difference of 1679 ml (95% Cl = 1289ml –2069 ml; P<0.001) for patients with airway obstruction. While bronchodilator treatmentwas used, the median difference for normal patients with airway obstruction was 1751ml (95% Cl 1516 – 1985 ml; P<0.001).CONCLUSIONS: The results showed that treatment with bronchodilator did not makeTLC measurements similar when SBHe was compared to body plethysmography, neitherfor normal patients nor for patients with airway obstruction; this leads to the conclusionthat SBHe is not a reliable test for TLC measurements.OBJETIVO: A capacidade pulmonar total (CPT) pode ser medida através dapletismografia, de testes de diluição de gases e por planimetria radiográfica. Apletismografia constitui-se no padrão aúreo, base de comparação para os outrostestes. O teste de respiração única com hélio (TDHe), realizado em conjunto com adeterminação da capacidade de difusão com monóxido de carbono, subdimensionao volume pulmonar em pacientes com obstrução ao fluxo aéreo. O objetivo dopresente trabalho foi o de avaliar se o TDHe após broncodilatador aproximaria ovalor da CPT obtido pelo TDHe com o da pletismografia, otimizando o teste erotinizando-o após broncodilatador.MATERIAIS E MÉTODOS: Foram estudados 155 pacientes adultos, que realizaramtestes com determinação de volumes na Unidade de Fisiologia Pulmonar do Serviçode Pneumologia do Hospital de Clínicas de Porto Alegre. Dividiu-se os pacientes emdois grupos: os que foram submetidos ao TDHe sem broncodilatador e os que fizeramTDHe com broncodilatador. Cada grupo foi subdividido em dois subgrupos: normaise obstrutivos.RESULTADOS: Os valores da CPT obtidos com pletismografia foram superiores emtodos os grupos. No grupo sem broncodilatador, os valores de CPT tiveram umadiferença média de 934 ml (IC 95% de 657 a 1210; P<0,001) nos normais e de 1679 ml(IC 95% de 1289 a 2069; P<0,001) nos obstrutivos. Com o broncodilatador, a diferençamédia dos pacientes normais foi de 1111 ml (IC 95% de 706 a 1515; P<0,001) e nosobstrutivos a diferença foi de 1751 ml (IC 95% de 1516 a 1985; P<0,001).CONCLUSÕES: Os resultados demonstraram que o uso do broncodilatador nãoaproximou os valores da CPT do TDHe aos da pletismografia, tanto em indivíduosnormais como naqueles com doença obstrutiva das vias aéreas. O TDHE não seconstitui em teste fidedigno para determinação de volumes pulmonares absolutos.HCPA/FAMED/UFRGS2022-06-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125264Clinical & Biomedical Research; Vol. 20 No. 1 (2000): Revista HCPAClinical and Biomedical Research; v. 20 n. 1 (2000): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125264/85190http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMancopes, Paula Fontoura, Maria Ângela S.M. Barreto, Sérgio 2022-09-16T16:33:00Zoai:seer.ufrgs.br:article/125264Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-09-16T16:33Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator Determinação da capacidade pulmonar total: pletismografia versus método de diluição do hélio em respiração única após teste broncodilatador |
title |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator |
spellingShingle |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator Mancopes, Paula Testes de função pulmonar volumes pulmonares distúrbio ventilatório obstrutivo Pulmonary function tests lung volume airflow obstructive defect |
title_short |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator |
title_full |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator |
title_fullStr |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator |
title_full_unstemmed |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator |
title_sort |
Measurement of total lung capacity: plethysmography versus single breath helium method after treatment with bronchodilator |
author |
Mancopes, Paula |
author_facet |
Mancopes, Paula Fontoura, Maria Ângela S.M. Barreto, Sérgio |
author_role |
author |
author2 |
Fontoura, Maria Ângela S.M. Barreto, Sérgio |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Mancopes, Paula Fontoura, Maria Ângela S.M. Barreto, Sérgio |
dc.subject.por.fl_str_mv |
Testes de função pulmonar volumes pulmonares distúrbio ventilatório obstrutivo Pulmonary function tests lung volume airflow obstructive defect |
topic |
Testes de função pulmonar volumes pulmonares distúrbio ventilatório obstrutivo Pulmonary function tests lung volume airflow obstructive defect |
description |
OBJECTIVE: Total lung capacity (TLC) can be measured using body plethysmography,single-breath helium or RX planimetry. Body plethysmography is the goldstandard test,allowing comparison with other methods. The single breath helium method (SBHe),when used in association with CO2diffusing capacity, can estimate lung volumes inpatients with airway flow obstruction. The aim of the present study is to evaluate if TLCmeasured with SBHe after treatment with bronchodilator is similar to that obtained frombody plethysmography.MATERIALS AND METHODS: The sample included 155 adult patients submitted topulmonary function testing including lung volumes at the Pulmonary Physiology Unit,Pulmonary Department at Hospital de Clínicas de Porto Alegre. The patients were placedin two groups: one group underwent SBHe with bronchodilator, and the other group wassubmitted to SBHe without bronchodilator. Afterwards, each group was subdivided intotwo subgroups: normal patients and patients with airway obstruction.RESULTS: The TLC results obtained with the body plethysmography technique weregreater than the alternative methods for all groups. In the group without bronchodilatortreatment, there was a median difference of 934 ml (CI 95% = 657 ml – 1210 ml;P<0.001) for normal patients, and a median difference of 1679 ml (95% Cl = 1289ml –2069 ml; P<0.001) for patients with airway obstruction. While bronchodilator treatmentwas used, the median difference for normal patients with airway obstruction was 1751ml (95% Cl 1516 – 1985 ml; P<0.001).CONCLUSIONS: The results showed that treatment with bronchodilator did not makeTLC measurements similar when SBHe was compared to body plethysmography, neitherfor normal patients nor for patients with airway obstruction; this leads to the conclusionthat SBHe is not a reliable test for TLC measurements. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliado por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/125264 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/125264 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/125264/85190 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 20 No. 1 (2000): Revista HCPA Clinical and Biomedical Research; v. 20 n. 1 (2000): Revista HCPA 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
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1799767056917200896 |