Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity

Detalhes bibliográficos
Autor(a) principal: Santos, Eduardo da Silveira dos
Data de Publicação: 2016
Tipo de documento: Trabalho de conclusão de curso
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/184776
Resumo: A new series of 4-methyl-quinolines was synthesized as potential cruzain inhibitors using Doebner-Von Miller synthesis. The compounds (1a-f) are undergoing analysis in order to guarantee their purities and further explore their biological activity.
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spelling Santos, Eduardo da Silveira dosGnoatto, Simone Cristina Baggio2018-11-17T03:12:08Z2016http://hdl.handle.net/10183/184776001020636A new series of 4-methyl-quinolines was synthesized as potential cruzain inhibitors using Doebner-Von Miller synthesis. The compounds (1a-f) are undergoing analysis in order to guarantee their purities and further explore their biological activity.application/pdfengFarmáciaQuinolineDoebner-Von MillerCruzainTrypanosoma cruziChagas diseaseSynthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal do Rio Grande do SulFaculdade de FarmáciaPorto Alegre, BR-RS2016Farmáciagraduaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001020636.pdf.txt001020636.pdf.txtExtracted Texttext/plain56097http://www.lume.ufrgs.br/bitstream/10183/184776/2/001020636.pdf.txt69e456796cfded7520f252f1bf70885aMD52ORIGINAL001020636.pdfTexto completo (inglês)application/pdf1326560http://www.lume.ufrgs.br/bitstream/10183/184776/1/001020636.pdf0cd75f7463788e1cba07ac68102c2785MD5110183/1847762018-11-18 02:41:35.958791oai:www.lume.ufrgs.br:10183/184776Repositório InstitucionalPUBhttps://lume.ufrgs.br/oai/requestlume@ufrgs.bropendoar:2018-11-18T04:41:35Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
title Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
spellingShingle Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
Santos, Eduardo da Silveira dos
Farmácia
Quinoline
Doebner-Von Miller
Cruzain
Trypanosoma cruzi
Chagas disease
title_short Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
title_full Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
title_fullStr Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
title_full_unstemmed Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
title_sort Synthesis of substituted 4-methyl-quinolines as potential cruzain inhibitors toward anti-Trypanosoma cruzi activity
author Santos, Eduardo da Silveira dos
author_facet Santos, Eduardo da Silveira dos
author_role author
dc.contributor.author.fl_str_mv Santos, Eduardo da Silveira dos
dc.contributor.advisor1.fl_str_mv Gnoatto, Simone Cristina Baggio
contributor_str_mv Gnoatto, Simone Cristina Baggio
dc.subject.por.fl_str_mv Farmácia
topic Farmácia
Quinoline
Doebner-Von Miller
Cruzain
Trypanosoma cruzi
Chagas disease
dc.subject.eng.fl_str_mv Quinoline
Doebner-Von Miller
Cruzain
Trypanosoma cruzi
Chagas disease
description A new series of 4-methyl-quinolines was synthesized as potential cruzain inhibitors using Doebner-Von Miller synthesis. The compounds (1a-f) are undergoing analysis in order to guarantee their purities and further explore their biological activity.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2018-11-17T03:12:08Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/bachelorThesis
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/184776
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