Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/198941 |
Resumo: | Background: Risk factors for ischemic stroke are mostly known, but it is still unclear in most countries, what are their combined population-attributable risk percent (PAR%). In a case-control study the individual odds ratios (ORs) and the individual and combined PAR%, including risk factors not addressed in previous studies were estimated. Methods: Cases and controls were selected from patients attending to an emergency department. Cases were patients aged with 45 years or more with the first episode of ischemic stroke, characterized by a focal neurological deficit or change in the mental status occurring during the previous 24 hours. Controls, matched to cases by age and gender, were selected from patients without neurological complaints. Results: 133 cases and 272 controls were studied. Odds ratios for ischemic stroke were: atrial fibrillation (27.3; CI 95% 7.5– 99.9), left ventricular hypertrophy (20.3; CI 95% 8.8–46.4), history of hypertension (11.2; CI 95% 5.4–23.3), physical inactivity (6.6; CI 95% 3.3–13.1), low levels of HDL-cholesterol (5.0; CI 95%2.8–8.9), heavy smoking (2.8; CI 95% 1.5–5.0), carotid bruit (2.5; CI 95% 1.3–4.6), diabetes (2.4; CI 95% 1.4–4.0) and alcohol abuse (2.1; CI 95% 1.1–4.0), The combination of these risk factors accounted for 98.9% (95% CI; 96.4%–99.7%) of the PAR% for all stroke. Conclusions: Nine risk factors, easily identified, explain almost 100% of the population attributable risk for ischemic stroke. |
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Mallmann, Adroaldo BasseggioFuchs, Sandra Cristina Pereira CostaGus, MiguelFuchs, Flávio DanniMoreira, Leila Beltrami2019-09-07T02:33:26Z20121932-6203http://hdl.handle.net/10183/198941000857342Background: Risk factors for ischemic stroke are mostly known, but it is still unclear in most countries, what are their combined population-attributable risk percent (PAR%). In a case-control study the individual odds ratios (ORs) and the individual and combined PAR%, including risk factors not addressed in previous studies were estimated. Methods: Cases and controls were selected from patients attending to an emergency department. Cases were patients aged with 45 years or more with the first episode of ischemic stroke, characterized by a focal neurological deficit or change in the mental status occurring during the previous 24 hours. Controls, matched to cases by age and gender, were selected from patients without neurological complaints. Results: 133 cases and 272 controls were studied. Odds ratios for ischemic stroke were: atrial fibrillation (27.3; CI 95% 7.5– 99.9), left ventricular hypertrophy (20.3; CI 95% 8.8–46.4), history of hypertension (11.2; CI 95% 5.4–23.3), physical inactivity (6.6; CI 95% 3.3–13.1), low levels of HDL-cholesterol (5.0; CI 95%2.8–8.9), heavy smoking (2.8; CI 95% 1.5–5.0), carotid bruit (2.5; CI 95% 1.3–4.6), diabetes (2.4; CI 95% 1.4–4.0) and alcohol abuse (2.1; CI 95% 1.1–4.0), The combination of these risk factors accounted for 98.9% (95% CI; 96.4%–99.7%) of the PAR% for all stroke. Conclusions: Nine risk factors, easily identified, explain almost 100% of the population attributable risk for ischemic stroke.application/pdfengPLoS ONE. San Francisco. Vol. 7, no. 4 (Apr. 2012), e35680 [4 p.]AVC isquêmicoEstudo de casoFatores de riscoPopulation-attributable risks for ischemic stroke in a community in south Brazil : a case-control studyEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT000857342.pdf.txt000857342.pdf.txtExtracted Texttext/plain24879http://www.lume.ufrgs.br/bitstream/10183/198941/2/000857342.pdf.txt148b2e65c1301db3b40df7e3d0199885MD52ORIGINAL000857342.pdfTexto completo (inglês)application/pdf590118http://www.lume.ufrgs.br/bitstream/10183/198941/1/000857342.pdfb0951a891b0f1fe4f86139e7ac06ead8MD5110183/1989412023-01-20 06:01:09.68029oai:www.lume.ufrgs.br:10183/198941Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-01-20T08:01:09Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
title |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
spellingShingle |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study Mallmann, Adroaldo Basseggio AVC isquêmico Estudo de caso Fatores de risco |
title_short |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
title_full |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
title_fullStr |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
title_full_unstemmed |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
title_sort |
Population-attributable risks for ischemic stroke in a community in south Brazil : a case-control study |
author |
Mallmann, Adroaldo Basseggio |
author_facet |
Mallmann, Adroaldo Basseggio Fuchs, Sandra Cristina Pereira Costa Gus, Miguel Fuchs, Flávio Danni Moreira, Leila Beltrami |
author_role |
author |
author2 |
Fuchs, Sandra Cristina Pereira Costa Gus, Miguel Fuchs, Flávio Danni Moreira, Leila Beltrami |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Mallmann, Adroaldo Basseggio Fuchs, Sandra Cristina Pereira Costa Gus, Miguel Fuchs, Flávio Danni Moreira, Leila Beltrami |
dc.subject.por.fl_str_mv |
AVC isquêmico Estudo de caso Fatores de risco |
topic |
AVC isquêmico Estudo de caso Fatores de risco |
description |
Background: Risk factors for ischemic stroke are mostly known, but it is still unclear in most countries, what are their combined population-attributable risk percent (PAR%). In a case-control study the individual odds ratios (ORs) and the individual and combined PAR%, including risk factors not addressed in previous studies were estimated. Methods: Cases and controls were selected from patients attending to an emergency department. Cases were patients aged with 45 years or more with the first episode of ischemic stroke, characterized by a focal neurological deficit or change in the mental status occurring during the previous 24 hours. Controls, matched to cases by age and gender, were selected from patients without neurological complaints. Results: 133 cases and 272 controls were studied. Odds ratios for ischemic stroke were: atrial fibrillation (27.3; CI 95% 7.5– 99.9), left ventricular hypertrophy (20.3; CI 95% 8.8–46.4), history of hypertension (11.2; CI 95% 5.4–23.3), physical inactivity (6.6; CI 95% 3.3–13.1), low levels of HDL-cholesterol (5.0; CI 95%2.8–8.9), heavy smoking (2.8; CI 95% 1.5–5.0), carotid bruit (2.5; CI 95% 1.3–4.6), diabetes (2.4; CI 95% 1.4–4.0) and alcohol abuse (2.1; CI 95% 1.1–4.0), The combination of these risk factors accounted for 98.9% (95% CI; 96.4%–99.7%) of the PAR% for all stroke. Conclusions: Nine risk factors, easily identified, explain almost 100% of the population attributable risk for ischemic stroke. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
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2019-09-07T02:33:26Z |
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Estrangeiro info:eu-repo/semantics/article |
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eng |
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PLoS ONE. San Francisco. Vol. 7, no. 4 (Apr. 2012), e35680 [4 p.] |
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