Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/141111 |
Resumo: | PURPOSE: To evaluate experimental cranial vault reconstructions, by combining bone morphogenetic protein type 2 (BMP-2) and different matrices.METHODS: Fourty-nine animals were initially included (seven per group). We designed an experimental, open, prospective and comparative study, divided in seven groups: 1 – BMP-2+calcium phosphate (BT); 2 – BMP-2+acellular dermal matrix (BM); 3 – BMP-2+calcium alginate (BA); 4 – TCP; 5 – MDM; 6 – ALG; 7 – Bone autograft (BAG). A bone failure was created in left parietal bone of adult male mice. At the same procedure reconstruction was performed. After five weeks, animals were sacrificed, and reconstruction area was removed to histological analysis. After exclusion due to death or infection, thirty-eight animals were evaluated (BT=5; BM=6; BA=6; TCP=7; MDM=3; ALG=6; BAG=5).RESULTS: A higher incidence of infection has occurred in MDM group (57%, P=0.037). In cortical fusion, groups BAG, TCP, and BMP-2+TCP (BT) obtained the best scores, comparing to the others (P=0.00846). In new bone formation, groups BT, BAG, and TCP have presented the best scores (P=0.00835). When neovascularization was considered, best groups were BMP-2+MDM (BM), BMP-2+ALG (BA), TCP, and MDM (P=0.001695). BAG group was the best in bone marrow formation, followed by groups BT and TCP (P=0.008317). CONCLUSIONS: Bone morphogenetic protein type 2 increased bone regeneration in experimental skull reconstruction, especially when combined to calcium phosphate. Such association was even comparable to bone autograft, the gold-standard treatment, in some histological criteria. |
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Cavalcante, Kaoli PereiraCardoso, Luciana de SouzaSussella, RovanaBecker, Vanessa2016-05-14T02:08:10Z20160018-8158http://hdl.handle.net/10183/141111000990797PURPOSE: To evaluate experimental cranial vault reconstructions, by combining bone morphogenetic protein type 2 (BMP-2) and different matrices.METHODS: Fourty-nine animals were initially included (seven per group). We designed an experimental, open, prospective and comparative study, divided in seven groups: 1 – BMP-2+calcium phosphate (BT); 2 – BMP-2+acellular dermal matrix (BM); 3 – BMP-2+calcium alginate (BA); 4 – TCP; 5 – MDM; 6 – ALG; 7 – Bone autograft (BAG). A bone failure was created in left parietal bone of adult male mice. At the same procedure reconstruction was performed. After five weeks, animals were sacrificed, and reconstruction area was removed to histological analysis. After exclusion due to death or infection, thirty-eight animals were evaluated (BT=5; BM=6; BA=6; TCP=7; MDM=3; ALG=6; BAG=5).RESULTS: A higher incidence of infection has occurred in MDM group (57%, P=0.037). In cortical fusion, groups BAG, TCP, and BMP-2+TCP (BT) obtained the best scores, comparing to the others (P=0.00846). In new bone formation, groups BT, BAG, and TCP have presented the best scores (P=0.00835). When neovascularization was considered, best groups were BMP-2+MDM (BM), BMP-2+ALG (BA), TCP, and MDM (P=0.001695). BAG group was the best in bone marrow formation, followed by groups BT and TCP (P=0.008317). CONCLUSIONS: Bone morphogenetic protein type 2 increased bone regeneration in experimental skull reconstruction, especially when combined to calcium phosphate. Such association was even comparable to bone autograft, the gold-standard treatment, in some histological criteria.application/pdfengHydrobiologia. Vol.771, N.1 ,(2016), p.265-280Taxonomia vegetal : Algas : Brasil Rio Grande do SulBone and BonesBone TransplantationTissue EngineeringBone MatrixCraniofacial AbnormalitiesMiceTowards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirsEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000990797.pdf000990797.pdfTexto completo (inglês)application/pdf1782557http://www.lume.ufrgs.br/bitstream/10183/141111/1/000990797.pdf120598bb77fa499a0cd169903d12d096MD51TEXT000990797.pdf.txt000990797.pdf.txtExtracted Texttext/plain43636http://www.lume.ufrgs.br/bitstream/10183/141111/2/000990797.pdf.txtbef629731b79ded68cc77f5b4597e341MD52THUMBNAIL000990797.pdf.jpg000990797.pdf.jpgGenerated Thumbnailimage/jpeg1829http://www.lume.ufrgs.br/bitstream/10183/141111/3/000990797.pdf.jpg6fc02521cc767fd0e9c187770462c405MD5310183/1411112021-09-18 04:48:38.039726oai:www.lume.ufrgs.br:10183/141111Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-09-18T07:48:38Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
title |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
spellingShingle |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs Cavalcante, Kaoli Pereira Taxonomia vegetal : Algas : Brasil Rio Grande do Sul Bone and Bones Bone Transplantation Tissue Engineering Bone Matrix Craniofacial Abnormalities Mice |
title_short |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
title_full |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
title_fullStr |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
title_full_unstemmed |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
title_sort |
Towards a comprehension of Ceratium (Dinophyceae) invasion in Brazilian freshwaters:autoecology of C. furcoides in subtropical reservoirs |
author |
Cavalcante, Kaoli Pereira |
author_facet |
Cavalcante, Kaoli Pereira Cardoso, Luciana de Souza Sussella, Rovana Becker, Vanessa |
author_role |
author |
author2 |
Cardoso, Luciana de Souza Sussella, Rovana Becker, Vanessa |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Cavalcante, Kaoli Pereira Cardoso, Luciana de Souza Sussella, Rovana Becker, Vanessa |
dc.subject.por.fl_str_mv |
Taxonomia vegetal : Algas : Brasil Rio Grande do Sul |
topic |
Taxonomia vegetal : Algas : Brasil Rio Grande do Sul Bone and Bones Bone Transplantation Tissue Engineering Bone Matrix Craniofacial Abnormalities Mice |
dc.subject.eng.fl_str_mv |
Bone and Bones Bone Transplantation Tissue Engineering Bone Matrix Craniofacial Abnormalities Mice |
description |
PURPOSE: To evaluate experimental cranial vault reconstructions, by combining bone morphogenetic protein type 2 (BMP-2) and different matrices.METHODS: Fourty-nine animals were initially included (seven per group). We designed an experimental, open, prospective and comparative study, divided in seven groups: 1 – BMP-2+calcium phosphate (BT); 2 – BMP-2+acellular dermal matrix (BM); 3 – BMP-2+calcium alginate (BA); 4 – TCP; 5 – MDM; 6 – ALG; 7 – Bone autograft (BAG). A bone failure was created in left parietal bone of adult male mice. At the same procedure reconstruction was performed. After five weeks, animals were sacrificed, and reconstruction area was removed to histological analysis. After exclusion due to death or infection, thirty-eight animals were evaluated (BT=5; BM=6; BA=6; TCP=7; MDM=3; ALG=6; BAG=5).RESULTS: A higher incidence of infection has occurred in MDM group (57%, P=0.037). In cortical fusion, groups BAG, TCP, and BMP-2+TCP (BT) obtained the best scores, comparing to the others (P=0.00846). In new bone formation, groups BT, BAG, and TCP have presented the best scores (P=0.00835). When neovascularization was considered, best groups were BMP-2+MDM (BM), BMP-2+ALG (BA), TCP, and MDM (P=0.001695). BAG group was the best in bone marrow formation, followed by groups BT and TCP (P=0.008317). CONCLUSIONS: Bone morphogenetic protein type 2 increased bone regeneration in experimental skull reconstruction, especially when combined to calcium phosphate. Such association was even comparable to bone autograft, the gold-standard treatment, in some histological criteria. |
publishDate |
2016 |
dc.date.accessioned.fl_str_mv |
2016-05-14T02:08:10Z |
dc.date.issued.fl_str_mv |
2016 |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
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format |
article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/141111 |
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0018-8158 |
dc.identifier.nrb.pt_BR.fl_str_mv |
000990797 |
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http://hdl.handle.net/10183/141111 |
dc.language.iso.fl_str_mv |
eng |
language |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Hydrobiologia. Vol.771, N.1 ,(2016), p.265-280 |
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openAccess |
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