Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/26837 |
Resumo: | Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS). |
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Siqueira, Felipe SegabinazziCrestani, AllanCanto, Rômulo Faria SantosEifler-Lima, Vera Lucia2010-11-23T04:19:31Z2010http://hdl.handle.net/10183/26837000758698Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS).application/pdfporSíntese orgânica em fase sólidaDihydropirimidinonesBiginelli reactionSolid-phase organic synthesisSíntese em fase sólida convergente de derivados 5-amidos diidropirimidinonasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal do Rio Grande do SulFaculdade de FarmáciaPorto Alegre, BR-RS2010Farmáciagraduaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000758698.pdf000758698.pdfTexto completoapplication/pdf264777http://www.lume.ufrgs.br/bitstream/10183/26837/1/000758698.pdf5b3f685e45ce3c7dcbe912a2a5f39989MD51TEXT000758698.pdf.txt000758698.pdf.txtExtracted Texttext/plain21586http://www.lume.ufrgs.br/bitstream/10183/26837/2/000758698.pdf.txtc17ec508d1f4568f123c4bfa75e6e9aeMD52THUMBNAIL000758698.pdf.jpg000758698.pdf.jpgGenerated Thumbnailimage/jpeg983http://www.lume.ufrgs.br/bitstream/10183/26837/3/000758698.pdf.jpga0c52434b0eae741c23be7c17214182bMD5310183/268372018-10-18 07:39:20.294oai:www.lume.ufrgs.br:10183/26837Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-18T10:39:20Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
title |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
spellingShingle |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas Siqueira, Felipe Segabinazzi Síntese orgânica em fase sólida Dihydropirimidinones Biginelli reaction Solid-phase organic synthesis |
title_short |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
title_full |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
title_fullStr |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
title_full_unstemmed |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
title_sort |
Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas |
author |
Siqueira, Felipe Segabinazzi |
author_facet |
Siqueira, Felipe Segabinazzi Crestani, Allan Canto, Rômulo Faria Santos |
author_role |
author |
author2 |
Crestani, Allan Canto, Rômulo Faria Santos |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Siqueira, Felipe Segabinazzi Crestani, Allan Canto, Rômulo Faria Santos |
dc.contributor.advisor1.fl_str_mv |
Eifler-Lima, Vera Lucia |
contributor_str_mv |
Eifler-Lima, Vera Lucia |
dc.subject.por.fl_str_mv |
Síntese orgânica em fase sólida |
topic |
Síntese orgânica em fase sólida Dihydropirimidinones Biginelli reaction Solid-phase organic synthesis |
dc.subject.eng.fl_str_mv |
Dihydropirimidinones Biginelli reaction Solid-phase organic synthesis |
description |
Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS). |
publishDate |
2010 |
dc.date.accessioned.fl_str_mv |
2010-11-23T04:19:31Z |
dc.date.issued.fl_str_mv |
2010 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
format |
bachelorThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/26837 |
dc.identifier.nrb.pt_BR.fl_str_mv |
000758698 |
url |
http://hdl.handle.net/10183/26837 |
identifier_str_mv |
000758698 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
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Repositório Institucional da UFRGS |
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