Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas

Detalhes bibliográficos
Autor(a) principal: Siqueira, Felipe Segabinazzi
Data de Publicação: 2010
Outros Autores: Crestani, Allan, Canto, Rômulo Faria Santos
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/26837
Resumo: Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS).
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spelling Siqueira, Felipe SegabinazziCrestani, AllanCanto, Rômulo Faria SantosEifler-Lima, Vera Lucia2010-11-23T04:19:31Z2010http://hdl.handle.net/10183/26837000758698Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS).application/pdfporSíntese orgânica em fase sólidaDihydropirimidinonesBiginelli reactionSolid-phase organic synthesisSíntese em fase sólida convergente de derivados 5-amidos diidropirimidinonasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal do Rio Grande do SulFaculdade de FarmáciaPorto Alegre, BR-RS2010Farmáciagraduaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000758698.pdf000758698.pdfTexto completoapplication/pdf264777http://www.lume.ufrgs.br/bitstream/10183/26837/1/000758698.pdf5b3f685e45ce3c7dcbe912a2a5f39989MD51TEXT000758698.pdf.txt000758698.pdf.txtExtracted Texttext/plain21586http://www.lume.ufrgs.br/bitstream/10183/26837/2/000758698.pdf.txtc17ec508d1f4568f123c4bfa75e6e9aeMD52THUMBNAIL000758698.pdf.jpg000758698.pdf.jpgGenerated Thumbnailimage/jpeg983http://www.lume.ufrgs.br/bitstream/10183/26837/3/000758698.pdf.jpga0c52434b0eae741c23be7c17214182bMD5310183/268372018-10-18 07:39:20.294oai:www.lume.ufrgs.br:10183/26837Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-18T10:39:20Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
title Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
spellingShingle Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
Siqueira, Felipe Segabinazzi
Síntese orgânica em fase sólida
Dihydropirimidinones
Biginelli reaction
Solid-phase organic synthesis
title_short Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
title_full Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
title_fullStr Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
title_full_unstemmed Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
title_sort Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
author Siqueira, Felipe Segabinazzi
author_facet Siqueira, Felipe Segabinazzi
Crestani, Allan
Canto, Rômulo Faria Santos
author_role author
author2 Crestani, Allan
Canto, Rômulo Faria Santos
author2_role author
author
dc.contributor.author.fl_str_mv Siqueira, Felipe Segabinazzi
Crestani, Allan
Canto, Rômulo Faria Santos
dc.contributor.advisor1.fl_str_mv Eifler-Lima, Vera Lucia
contributor_str_mv Eifler-Lima, Vera Lucia
dc.subject.por.fl_str_mv Síntese orgânica em fase sólida
topic Síntese orgânica em fase sólida
Dihydropirimidinones
Biginelli reaction
Solid-phase organic synthesis
dc.subject.eng.fl_str_mv Dihydropirimidinones
Biginelli reaction
Solid-phase organic synthesis
description Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS).
publishDate 2010
dc.date.accessioned.fl_str_mv 2010-11-23T04:19:31Z
dc.date.issued.fl_str_mv 2010
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/26837
dc.identifier.nrb.pt_BR.fl_str_mv 000758698
url http://hdl.handle.net/10183/26837
identifier_str_mv 000758698
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