Toward precision psychiatry in bipolar disorder : staging 2.0
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/187754 |
Resumo: | Personalized treatment is defined as choosing the “right treatment for the right person at the right time.” Although psychiatry has not yet reached this level of precision, we are on the way thanks to recent technological developments that may aid to detect plausible molecular and genetic markers. At the moment there are some models that are contributing to precision psychiatry through the concept of staging. While staging was initially presented as a way to categorize patients according to clinical presentation, course, and illness severity, current stagingmodels integratemultiple levels of information that can help to define each patient’s characteristics, severity, and prognosis in a more precise and individualized way. Moreover, staging might serve as the foundation to create a clinical decision-making algorithm on the basis of the patient’s stage. In this review we will summarize the evolution of the bipolar disorder staging model in relation to the new discoveries on the neurobiology of bipolar disorder. Furthermore, we will discuss how the latest and future progress in psychiatry might transform current staging models into precision staging models. |
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Salagre Muñoz, EstelaDodd, SeetalSeguel, Alberto Ignacio AedoRosa, Adriane RibeiroGuadall, Silvia AmorettiEspinosa, Justo Emilio PinzónReinares, MariaBerk, MichaelKapczinski, Flávio PereiraVieta, EduardGrande, Iria2019-01-15T04:03:20Z20181664-0640http://hdl.handle.net/10183/187754001084325Personalized treatment is defined as choosing the “right treatment for the right person at the right time.” Although psychiatry has not yet reached this level of precision, we are on the way thanks to recent technological developments that may aid to detect plausible molecular and genetic markers. At the moment there are some models that are contributing to precision psychiatry through the concept of staging. While staging was initially presented as a way to categorize patients according to clinical presentation, course, and illness severity, current stagingmodels integratemultiple levels of information that can help to define each patient’s characteristics, severity, and prognosis in a more precise and individualized way. Moreover, staging might serve as the foundation to create a clinical decision-making algorithm on the basis of the patient’s stage. In this review we will summarize the evolution of the bipolar disorder staging model in relation to the new discoveries on the neurobiology of bipolar disorder. Furthermore, we will discuss how the latest and future progress in psychiatry might transform current staging models into precision staging models.application/pdfengFrontiers in psychiatry. Lausanne. Vol. 9 (Nov. 2018), 641, 15 p.Transtorno bipolarBiomarcadoresPrevenção de doençasPsiquiatriaBipolar disorderStagingBiomarkersPersonalized psychiatryPreventionToward precision psychiatry in bipolar disorder : staging 2.0Estrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001084325.pdf.txt001084325.pdf.txtExtracted Texttext/plain88902http://www.lume.ufrgs.br/bitstream/10183/187754/2/001084325.pdf.txtff38b395cd465258e086f7407acb894cMD52ORIGINAL001084325.pdfTexto completo (inglês)application/pdf935537http://www.lume.ufrgs.br/bitstream/10183/187754/1/001084325.pdf380398d8d4e8b0a44f1e0d354799bd9eMD5110183/1877542019-01-16 04:11:28.31617oai:www.lume.ufrgs.br:10183/187754Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-01-16T06:11:28Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
title |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
spellingShingle |
Toward precision psychiatry in bipolar disorder : staging 2.0 Salagre Muñoz, Estela Transtorno bipolar Biomarcadores Prevenção de doenças Psiquiatria Bipolar disorder Staging Biomarkers Personalized psychiatry Prevention |
title_short |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
title_full |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
title_fullStr |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
title_full_unstemmed |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
title_sort |
Toward precision psychiatry in bipolar disorder : staging 2.0 |
author |
Salagre Muñoz, Estela |
author_facet |
Salagre Muñoz, Estela Dodd, Seetal Seguel, Alberto Ignacio Aedo Rosa, Adriane Ribeiro Guadall, Silvia Amoretti Espinosa, Justo Emilio Pinzón Reinares, Maria Berk, Michael Kapczinski, Flávio Pereira Vieta, Eduard Grande, Iria |
author_role |
author |
author2 |
Dodd, Seetal Seguel, Alberto Ignacio Aedo Rosa, Adriane Ribeiro Guadall, Silvia Amoretti Espinosa, Justo Emilio Pinzón Reinares, Maria Berk, Michael Kapczinski, Flávio Pereira Vieta, Eduard Grande, Iria |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Salagre Muñoz, Estela Dodd, Seetal Seguel, Alberto Ignacio Aedo Rosa, Adriane Ribeiro Guadall, Silvia Amoretti Espinosa, Justo Emilio Pinzón Reinares, Maria Berk, Michael Kapczinski, Flávio Pereira Vieta, Eduard Grande, Iria |
dc.subject.por.fl_str_mv |
Transtorno bipolar Biomarcadores Prevenção de doenças Psiquiatria |
topic |
Transtorno bipolar Biomarcadores Prevenção de doenças Psiquiatria Bipolar disorder Staging Biomarkers Personalized psychiatry Prevention |
dc.subject.eng.fl_str_mv |
Bipolar disorder Staging Biomarkers Personalized psychiatry Prevention |
description |
Personalized treatment is defined as choosing the “right treatment for the right person at the right time.” Although psychiatry has not yet reached this level of precision, we are on the way thanks to recent technological developments that may aid to detect plausible molecular and genetic markers. At the moment there are some models that are contributing to precision psychiatry through the concept of staging. While staging was initially presented as a way to categorize patients according to clinical presentation, course, and illness severity, current stagingmodels integratemultiple levels of information that can help to define each patient’s characteristics, severity, and prognosis in a more precise and individualized way. Moreover, staging might serve as the foundation to create a clinical decision-making algorithm on the basis of the patient’s stage. In this review we will summarize the evolution of the bipolar disorder staging model in relation to the new discoveries on the neurobiology of bipolar disorder. Furthermore, we will discuss how the latest and future progress in psychiatry might transform current staging models into precision staging models. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018 |
dc.date.accessioned.fl_str_mv |
2019-01-15T04:03:20Z |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/187754 |
dc.identifier.issn.pt_BR.fl_str_mv |
1664-0640 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001084325 |
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1664-0640 001084325 |
url |
http://hdl.handle.net/10183/187754 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Frontiers in psychiatry. Lausanne. Vol. 9 (Nov. 2018), 641, 15 p. |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Repositório Institucional da UFRGS |
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