Effects of obesity, energy restriction and neutering on the faecal microbiota of cats
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/253322 |
Resumo: | Surveys report that 25–57 % of cats are overweight or obese. The most evinced cause is neutering. Weight loss often fails; thus, new strategies are needed. Obesity has been associated with altered gut bacterial populations and increases in microbial dietary energy extraction, body weight and adiposity. This study aimed to determine whether alterations in intestinal bacteria were associated with obesity, energy restriction and neutering by characterising faecal microbiota using 16S rRNA gene sequencing in eight lean intact, eight lean neutered and eight obese neutered cats before and after 6 weeks of energy restriction. Lean neutered cats had a bacterial profile similar to obese rodents and humans, with a greater abundance (P<0·05) of Firmicutes and lower abundance (P <0·05) of Bacteroidetes compared with the other groups. The greater abundance of Firmicutes in lean neutered cats was due to a bloom in Peptostreptococcaceae. Obese cats had an 18 % reduction in fat mass after energy restriction (P<0·05). Energy reduction was concurrent with significant shifts in two low-abundance bacterial genera and trends in four additional genera. The greatest change was a reduction in the Firmicutes genus, Sarcina, from 4·54 to 0·65 % abundance after energy restriction. The short duration of energy restriction may explain why few bacterial changes were observed in the obese cats. Additional work is needed to understand how neutering, obesity and weight loss are related to changes in feline microbiota and how these microbial shifts affect host physiology. |
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Fischer, Manuela MarquesKessler, Alexandre de MelloKieffer, Dorothy A.Knotts, Trina A.Kim, KyoungmiWei, AlfredaRamsey, Jon. J.Fascetti, Andrea J.2023-01-02T05:09:04Z20170007-1145http://hdl.handle.net/10183/253322001154560Surveys report that 25–57 % of cats are overweight or obese. The most evinced cause is neutering. Weight loss often fails; thus, new strategies are needed. Obesity has been associated with altered gut bacterial populations and increases in microbial dietary energy extraction, body weight and adiposity. This study aimed to determine whether alterations in intestinal bacteria were associated with obesity, energy restriction and neutering by characterising faecal microbiota using 16S rRNA gene sequencing in eight lean intact, eight lean neutered and eight obese neutered cats before and after 6 weeks of energy restriction. Lean neutered cats had a bacterial profile similar to obese rodents and humans, with a greater abundance (P<0·05) of Firmicutes and lower abundance (P <0·05) of Bacteroidetes compared with the other groups. The greater abundance of Firmicutes in lean neutered cats was due to a bloom in Peptostreptococcaceae. Obese cats had an 18 % reduction in fat mass after energy restriction (P<0·05). Energy reduction was concurrent with significant shifts in two low-abundance bacterial genera and trends in four additional genera. The greatest change was a reduction in the Firmicutes genus, Sarcina, from 4·54 to 0·65 % abundance after energy restriction. The short duration of energy restriction may explain why few bacterial changes were observed in the obese cats. Additional work is needed to understand how neutering, obesity and weight loss are related to changes in feline microbiota and how these microbial shifts affect host physiology.application/pdfengBritish journal of nutrition. Wallingford. Vol. 118, no. 7 (Oct. 2017), p. 513-524Nutricao animalGatoFaecal microbiotFeline nutritionObesityNeutered catsEnergy restrictionEffects of obesity, energy restriction and neutering on the faecal microbiota of catsEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001154560.pdf.txt001154560.pdf.txtExtracted Texttext/plain55492http://www.lume.ufrgs.br/bitstream/10183/253322/2/001154560.pdf.txtad5a366049713908862f4dec5391584eMD52ORIGINAL001154560.pdfTexto completo (inglês)application/pdf1422229http://www.lume.ufrgs.br/bitstream/10183/253322/1/001154560.pdf4e6999aea1a8569ed36a7cca1b9a715fMD5110183/2533222023-01-04 06:01:52.711904oai:www.lume.ufrgs.br:10183/253322Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-01-04T08:01:52Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
title |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
spellingShingle |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats Fischer, Manuela Marques Nutricao animal Gato Faecal microbiot Feline nutrition Obesity Neutered cats Energy restriction |
title_short |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
title_full |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
title_fullStr |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
title_full_unstemmed |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
title_sort |
Effects of obesity, energy restriction and neutering on the faecal microbiota of cats |
author |
Fischer, Manuela Marques |
author_facet |
Fischer, Manuela Marques Kessler, Alexandre de Mello Kieffer, Dorothy A. Knotts, Trina A. Kim, Kyoungmi Wei, Alfreda Ramsey, Jon. J. Fascetti, Andrea J. |
author_role |
author |
author2 |
Kessler, Alexandre de Mello Kieffer, Dorothy A. Knotts, Trina A. Kim, Kyoungmi Wei, Alfreda Ramsey, Jon. J. Fascetti, Andrea J. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Fischer, Manuela Marques Kessler, Alexandre de Mello Kieffer, Dorothy A. Knotts, Trina A. Kim, Kyoungmi Wei, Alfreda Ramsey, Jon. J. Fascetti, Andrea J. |
dc.subject.por.fl_str_mv |
Nutricao animal Gato |
topic |
Nutricao animal Gato Faecal microbiot Feline nutrition Obesity Neutered cats Energy restriction |
dc.subject.eng.fl_str_mv |
Faecal microbiot Feline nutrition Obesity Neutered cats Energy restriction |
description |
Surveys report that 25–57 % of cats are overweight or obese. The most evinced cause is neutering. Weight loss often fails; thus, new strategies are needed. Obesity has been associated with altered gut bacterial populations and increases in microbial dietary energy extraction, body weight and adiposity. This study aimed to determine whether alterations in intestinal bacteria were associated with obesity, energy restriction and neutering by characterising faecal microbiota using 16S rRNA gene sequencing in eight lean intact, eight lean neutered and eight obese neutered cats before and after 6 weeks of energy restriction. Lean neutered cats had a bacterial profile similar to obese rodents and humans, with a greater abundance (P<0·05) of Firmicutes and lower abundance (P <0·05) of Bacteroidetes compared with the other groups. The greater abundance of Firmicutes in lean neutered cats was due to a bloom in Peptostreptococcaceae. Obese cats had an 18 % reduction in fat mass after energy restriction (P<0·05). Energy reduction was concurrent with significant shifts in two low-abundance bacterial genera and trends in four additional genera. The greatest change was a reduction in the Firmicutes genus, Sarcina, from 4·54 to 0·65 % abundance after energy restriction. The short duration of energy restriction may explain why few bacterial changes were observed in the obese cats. Additional work is needed to understand how neutering, obesity and weight loss are related to changes in feline microbiota and how these microbial shifts affect host physiology. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
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2023-01-02T05:09:04Z |
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Estrangeiro info:eu-repo/semantics/article |
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http://hdl.handle.net/10183/253322 |
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http://hdl.handle.net/10183/253322 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
British journal of nutrition. Wallingford. Vol. 118, no. 7 (Oct. 2017), p. 513-524 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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