Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/jspui/handle/123456789/23266 |
Resumo: | Gamma-band synchronization adjusts the timing of excitatory and inhibitory inputs to a neuron. Neurons in the visual cortex are selective for stimulus orientation because of dynamic interactions between excitatory and inhibitory inputs. We hypothesized that these interactions and hence also orientation selectivity vary during the gamma cycle. We determined for each spike its phase relative to the gamma cycle. As a function of gamma phase, we then determined spike rates and their orientation selectivity. Orientation selectivity was modulated by gamma phase. The firing rate of spiking activity that occurred close to a neuron’s mean gamma phase of firing was most orientation selective. This stimulus- selective signal could best be conveyed to postsynaptic neurons if it were not corrupted by noise correlations. Noise correlations between firing rates were modulated by gamma phase such that they were not statistically detectable for the spiking activity occurring close to a neuron’s mean gamma phase of firing. Thus, gamma-band synchronization produces spiking activity that carries maximal stimulus selectivity and minimal noise correlation in its firing rate, and at the same time synchronizes this spiking activity for maximal impact on postsynaptic targets. |
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Thilo WomelsdorfBruss LimaMartin VinckRobert OostenveldWolf SingerMaciel, Sergio Tulio NeuenschwanderPascal Fries2017-05-31T12:49:32Z2017-05-31T12:49:32Z2012-02-011091-6490https://repositorio.ufrn.br/jspui/handle/123456789/23266engoscillationprimary visual cortexneuronal codingneuronal tuninginformation theoryOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleGamma-band synchronization adjusts the timing of excitatory and inhibitory inputs to a neuron. Neurons in the visual cortex are selective for stimulus orientation because of dynamic interactions between excitatory and inhibitory inputs. We hypothesized that these interactions and hence also orientation selectivity vary during the gamma cycle. We determined for each spike its phase relative to the gamma cycle. As a function of gamma phase, we then determined spike rates and their orientation selectivity. Orientation selectivity was modulated by gamma phase. The firing rate of spiking activity that occurred close to a neuron’s mean gamma phase of firing was most orientation selective. This stimulus- selective signal could best be conveyed to postsynaptic neurons if it were not corrupted by noise correlations. Noise correlations between firing rates were modulated by gamma phase such that they were not statistically detectable for the spiking activity occurring close to a neuron’s mean gamma phase of firing. Thus, gamma-band synchronization produces spiking activity that carries maximal stimulus selectivity and minimal noise correlation in its firing rate, and at the same time synchronizes this spiking activity for maximal impact on postsynaptic targets.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle.pdfOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle.pdfArtigo completoapplication/pdf834682https://repositorio.ufrn.br/bitstream/123456789/23266/1/Orientation%20selectivity%20and%20noise%20correlation%20in%20awake%20monkey%20area%20V1%20are%20modulated%20by%20the%20gamma%20cycle.pdfc58e4e32edc23e0f8d866e4384419c82MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufrn.br/bitstream/123456789/23266/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle.pdf.txtOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle.pdf.txtExtracted texttext/plain45882https://repositorio.ufrn.br/bitstream/123456789/23266/5/Orientation%20selectivity%20and%20noise%20correlation%20in%20awake%20monkey%20area%20V1%20are%20modulated%20by%20the%20gamma%20cycle.pdf.txte8b57e91bad72ea632d0d744c694dd53MD55THUMBNAILOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle.pdf.jpgOrientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle.pdf.jpgIM Thumbnailimage/jpeg14395https://repositorio.ufrn.br/bitstream/123456789/23266/6/Orientation%20selectivity%20and%20noise%20correlation%20in%20awake%20monkey%20area%20V1%20are%20modulated%20by%20the%20gamma%20cycle.pdf.jpga3d2a62c3e27c7333131b0b622967bc5MD56123456789/232662021-07-09 20:02:17.873oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-07-09T23:02:17Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
title |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
spellingShingle |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle Thilo Womelsdorf oscillation primary visual cortex neuronal coding neuronal tuning information theory |
title_short |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
title_full |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
title_fullStr |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
title_full_unstemmed |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
title_sort |
Orientation selectivity and noise correlation in awake monkey area V1 are modulated by the gamma cycle |
author |
Thilo Womelsdorf |
author_facet |
Thilo Womelsdorf Bruss Lima Martin Vinck Robert Oostenveld Wolf Singer Maciel, Sergio Tulio Neuenschwander Pascal Fries |
author_role |
author |
author2 |
Bruss Lima Martin Vinck Robert Oostenveld Wolf Singer Maciel, Sergio Tulio Neuenschwander Pascal Fries |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Thilo Womelsdorf Bruss Lima Martin Vinck Robert Oostenveld Wolf Singer Maciel, Sergio Tulio Neuenschwander Pascal Fries |
dc.subject.por.fl_str_mv |
oscillation primary visual cortex neuronal coding neuronal tuning information theory |
topic |
oscillation primary visual cortex neuronal coding neuronal tuning information theory |
description |
Gamma-band synchronization adjusts the timing of excitatory and inhibitory inputs to a neuron. Neurons in the visual cortex are selective for stimulus orientation because of dynamic interactions between excitatory and inhibitory inputs. We hypothesized that these interactions and hence also orientation selectivity vary during the gamma cycle. We determined for each spike its phase relative to the gamma cycle. As a function of gamma phase, we then determined spike rates and their orientation selectivity. Orientation selectivity was modulated by gamma phase. The firing rate of spiking activity that occurred close to a neuron’s mean gamma phase of firing was most orientation selective. This stimulus- selective signal could best be conveyed to postsynaptic neurons if it were not corrupted by noise correlations. Noise correlations between firing rates were modulated by gamma phase such that they were not statistically detectable for the spiking activity occurring close to a neuron’s mean gamma phase of firing. Thus, gamma-band synchronization produces spiking activity that carries maximal stimulus selectivity and minimal noise correlation in its firing rate, and at the same time synchronizes this spiking activity for maximal impact on postsynaptic targets. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-02-01 |
dc.date.accessioned.fl_str_mv |
2017-05-31T12:49:32Z |
dc.date.available.fl_str_mv |
2017-05-31T12:49:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/jspui/handle/123456789/23266 |
dc.identifier.issn.none.fl_str_mv |
1091-6490 |
identifier_str_mv |
1091-6490 |
url |
https://repositorio.ufrn.br/jspui/handle/123456789/23266 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFRN instname:Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN |
instname_str |
Universidade Federal do Rio Grande do Norte (UFRN) |
instacron_str |
UFRN |
institution |
UFRN |
reponame_str |
Repositório Institucional da UFRN |
collection |
Repositório Institucional da UFRN |
bitstream.url.fl_str_mv |
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