.

Detalhes bibliográficos
Autor(a) principal: Contar, Juida de Deus Palma
Data de Publicação: 1992
Outros Autores: Fedatto Junior, Zelio, Contar, Angelo Palma
Tipo de documento: Artigo
Idioma: por
Título da fonte: Biotemas (Online)
Texto Completo: https://periodicos.ufsc.br/index.php/biotemas/article/view/22799
Resumo: In this study, the neuroleptic effects of two compounds of Stevia rebaudiana were evaluated. Thus, Wistar adult male rats were submitted to Steviolbioside (120 and 240 mg/kg) and Isosteviol compounds (120, 160, 200 and 240 mg/kg) by i.p. injections. These substances were diluted in destilated water 9 pH and the Haloperidol (2 mg/kg), also infected i.p., used as a standarddrug for evaluate catatonic and palpebral ptosis responses. Animals submitted to Isosteviol exhibited significant catatonic and palpebral ptosis responses. It has been concluded that Isosteviol toxicity should be more investigated.
id UFSC-14_e25b447c4c2ab690f73a891b52071eec
oai_identifier_str oai:periodicos.ufsc.br:article/22799
network_acronym_str UFSC-14
network_name_str Biotemas (Online)
repository_id_str
spelling .Estudos dos efeitos neurolépticos de dois compostos derivados da Stevia rebaudianaIn this study, the neuroleptic effects of two compounds of Stevia rebaudiana were evaluated. Thus, Wistar adult male rats were submitted to Steviolbioside (120 and 240 mg/kg) and Isosteviol compounds (120, 160, 200 and 240 mg/kg) by i.p. injections. These substances were diluted in destilated water 9 pH and the Haloperidol (2 mg/kg), also infected i.p., used as a standarddrug for evaluate catatonic and palpebral ptosis responses. Animals submitted to Isosteviol exhibited significant catatonic and palpebral ptosis responses. It has been concluded that Isosteviol toxicity should be more investigated.Dois compostos de Stevia rebaudiana foram analisados, com o objetivo de avaliar os seus efeitos neurolépticos. Os compostos Steviolbioside (120 e 240 mg/kg) e Isosteviol (120, 160, 200 e 240 mg/kg) foram administrados, via i.p., em ratos Wistar adultos. Os dois compostos foram diluídos em água destilada com pH 9 e o Haloperiodol (2 mg/kg), administrado também via i.p., foi utilizado como droga padrão para catatonia e ptose palpebral. Somente os animais tratados com Isosteviol exibiram ptose palpebral e catatonia de forma significativa. Concluiu-se que a toxidade do Isosteviol deve ser alvo de maiores investigações.Universidade Federal de Santa Catarina1992-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufsc.br/index.php/biotemas/article/view/2279910.5007/%xBiotemas; v. 5 n. 2 (1992); 87-922175-79250103-1643reponame:Biotemas (Online)instname:Universidade Federal de Santa Catarina (UFSC)instacron:UFSCporhttps://periodicos.ufsc.br/index.php/biotemas/article/view/22799/20765Copyright (c) 1992 Juida de Deus Palma Contar, Zelio Fedatto Junior, Angelo Palma Contarinfo:eu-repo/semantics/openAccessContar, Juida de Deus PalmaFedatto Junior, ZelioContar, Angelo Palma2012-01-24T14:12:04Zoai:periodicos.ufsc.br:article/22799Revistahttp://www.biotemas.ufsc.br/index.htmPUBhttps://periodicos.ufsc.br/index.php/biotemas/oai||carlospinto@ccb.ufsc.br2175-79250103-1643opendoar:2012-01-24T14:12:04Biotemas (Online) - Universidade Federal de Santa Catarina (UFSC)false
dc.title.none.fl_str_mv .
Estudos dos efeitos neurolépticos de dois compostos derivados da Stevia rebaudiana
title .
spellingShingle .
Contar, Juida de Deus Palma
title_short .
title_full .
title_fullStr .
title_full_unstemmed .
title_sort .
author Contar, Juida de Deus Palma
author_facet Contar, Juida de Deus Palma
Fedatto Junior, Zelio
Contar, Angelo Palma
author_role author
author2 Fedatto Junior, Zelio
Contar, Angelo Palma
author2_role author
author
dc.contributor.author.fl_str_mv Contar, Juida de Deus Palma
Fedatto Junior, Zelio
Contar, Angelo Palma
description In this study, the neuroleptic effects of two compounds of Stevia rebaudiana were evaluated. Thus, Wistar adult male rats were submitted to Steviolbioside (120 and 240 mg/kg) and Isosteviol compounds (120, 160, 200 and 240 mg/kg) by i.p. injections. These substances were diluted in destilated water 9 pH and the Haloperidol (2 mg/kg), also infected i.p., used as a standarddrug for evaluate catatonic and palpebral ptosis responses. Animals submitted to Isosteviol exhibited significant catatonic and palpebral ptosis responses. It has been concluded that Isosteviol toxicity should be more investigated.
publishDate 1992
dc.date.none.fl_str_mv 1992-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufsc.br/index.php/biotemas/article/view/22799
10.5007/%x
url https://periodicos.ufsc.br/index.php/biotemas/article/view/22799
identifier_str_mv 10.5007/%x
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufsc.br/index.php/biotemas/article/view/22799/20765
dc.rights.driver.fl_str_mv Copyright (c) 1992 Juida de Deus Palma Contar, Zelio Fedatto Junior, Angelo Palma Contar
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 1992 Juida de Deus Palma Contar, Zelio Fedatto Junior, Angelo Palma Contar
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Catarina
publisher.none.fl_str_mv Universidade Federal de Santa Catarina
dc.source.none.fl_str_mv Biotemas; v. 5 n. 2 (1992); 87-92
2175-7925
0103-1643
reponame:Biotemas (Online)
instname:Universidade Federal de Santa Catarina (UFSC)
instacron:UFSC
instname_str Universidade Federal de Santa Catarina (UFSC)
instacron_str UFSC
institution UFSC
reponame_str Biotemas (Online)
collection Biotemas (Online)
repository.name.fl_str_mv Biotemas (Online) - Universidade Federal de Santa Catarina (UFSC)
repository.mail.fl_str_mv ||carlospinto@ccb.ufsc.br
_version_ 1799940551850590208

Registros relacionados