Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients
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Publication Date: | 2012 |
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Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNIFESP |
Download full: | http://repositorio.unifesp.br/handle/11600/7092 http://dx.doi.org/10.1590/S0100-879X2012007500025 |
Summary: | The objectives of this study were to evaluate and compare the use of linear and nonlinear methods for analysis of heart rate variability (HRV) in healthy subjects and in patients after acute myocardial infarction (AMI). Heart rate (HR) was recorded for 15 min in the supine position in 10 patients with AMI taking β-blockers (aged 57 ± 9 years) and in 11 healthy subjects (aged 53 ± 4 years). HRV was analyzed in the time domain (RMSSD and RMSM), the frequency domain using low- and high-frequency bands in normalized units (nu; LFnu and HFnu) and the LF/HF ratio and approximate entropy (ApEn) were determined. There was a correlation (P < 0.05) of RMSSD, RMSM, LFnu, HFnu, and the LF/HF ratio index with the ApEn of the AMI group on the 2nd (r = 0.87, 0.65, 0.72, 0.72, and 0.64) and 7th day (r = 0.88, 0.70, 0.69, 0.69, and 0.87) and of the healthy group (r = 0.63, 0.71, 0.63, 0.63, and 0.74), respectively. The median HRV indexes of the AMI group on the 2nd and 7th day differed from the healthy group (P < 0.05): RMSSD = 10.37, 19.95, 24.81; RMSM = 23.47, 31.96, 43.79; LFnu = 0.79, 0.79, 0.62; HFnu = 0.20, 0.20, 0.37; LF/HF ratio = 3.87, 3.94, 1.65; ApEn = 1.01, 1.24, 1.31, respectively. There was agreement between the methods, suggesting that these have the same power to evaluate autonomic modulation of HR in both AMI patients and healthy subjects. AMI contributed to a reduction in cardiac signal irregularity, higher sympathetic modulation and lower vagal modulation. |
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Kunz, V.c.Borges, E.n.Coelho, Regina Célia [UNIFESP]Gubolino, L.a.Martins, L.e.b.Silva, E.Universidade Federal de São Carlos Departamento de Fisioterapia Núcleo de Pesquisa em Exercício FísicoUniversidade Metodista de Piracicaba Faculdade de Ciências da SaúdeUniversidade Federal de São Paulo (UNIFESP)Unidade Coronariana do Hospital dos Fornecedores de Cana de PiracicabaUniversidade Estadual de Campinas (UNICAMP)2015-06-14T13:43:44Z2015-06-14T13:43:44Z2012-05-01Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 45, n. 5, p. 450-458, 2012.0100-879Xhttp://repositorio.unifesp.br/handle/11600/7092http://dx.doi.org/10.1590/S0100-879X2012007500025S0100-879X2012000500011.pdfS0100-879X201200050001110.1590/S0100-879X2012007500025WOS:000303940200011The objectives of this study were to evaluate and compare the use of linear and nonlinear methods for analysis of heart rate variability (HRV) in healthy subjects and in patients after acute myocardial infarction (AMI). Heart rate (HR) was recorded for 15 min in the supine position in 10 patients with AMI taking β-blockers (aged 57 ± 9 years) and in 11 healthy subjects (aged 53 ± 4 years). HRV was analyzed in the time domain (RMSSD and RMSM), the frequency domain using low- and high-frequency bands in normalized units (nu; LFnu and HFnu) and the LF/HF ratio and approximate entropy (ApEn) were determined. There was a correlation (P < 0.05) of RMSSD, RMSM, LFnu, HFnu, and the LF/HF ratio index with the ApEn of the AMI group on the 2nd (r = 0.87, 0.65, 0.72, 0.72, and 0.64) and 7th day (r = 0.88, 0.70, 0.69, 0.69, and 0.87) and of the healthy group (r = 0.63, 0.71, 0.63, 0.63, and 0.74), respectively. The median HRV indexes of the AMI group on the 2nd and 7th day differed from the healthy group (P < 0.05): RMSSD = 10.37, 19.95, 24.81; RMSM = 23.47, 31.96, 43.79; LFnu = 0.79, 0.79, 0.62; HFnu = 0.20, 0.20, 0.37; LF/HF ratio = 3.87, 3.94, 1.65; ApEn = 1.01, 1.24, 1.31, respectively. There was agreement between the methods, suggesting that these have the same power to evaluate autonomic modulation of HR in both AMI patients and healthy subjects. AMI contributed to a reduction in cardiac signal irregularity, higher sympathetic modulation and lower vagal modulation.Universidade Federal de São Carlos Departamento de Fisioterapia Núcleo de Pesquisa em Exercício FísicoUniversidade Metodista de Piracicaba Faculdade de Ciências da SaúdeUniversidade Federal de São Paulo (UNIFESP) Instituto de Ciência e TecnologiaUnidade Coronariana do Hospital dos Fornecedores de Cana de PiracicabaUniversidade Estadual de Campinas Faculdade de Educação FísicaUNIFESP, Instituto de Ciência e TecnologiaSciELO450-458engAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological ResearchMyocardial infarctionHeart rate variabilityAutonomic nervous systemSpectral analysisNonlinear dynamicsLinear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS0100-879X2012000500011.pdfapplication/pdf1912530${dspace.ui.url}/bitstream/11600/7092/1/S0100-879X2012000500011.pdfbdad2f19cf6cd72c09ab3828c7d05acaMD51open accessTEXTS0100-879X2012000500011.pdf.txtS0100-879X2012000500011.pdf.txtExtracted texttext/plain35861${dspace.ui.url}/bitstream/11600/7092/9/S0100-879X2012000500011.pdf.txt7892855e971efa973c74a56fe72800d7MD59open accessTHUMBNAILS0100-879X2012000500011.pdf.jpgS0100-879X2012000500011.pdf.jpgIM Thumbnailimage/jpeg9393${dspace.ui.url}/bitstream/11600/7092/11/S0100-879X2012000500011.pdf.jpgba9af4c79b27ce476fc0eeeef2bc1067MD511open access11600/70922023-06-05 19:08:23.003open accessoai:repositorio.unifesp.br:11600/7092Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:08:23Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
title |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
spellingShingle |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients Kunz, V.c. Myocardial infarction Heart rate variability Autonomic nervous system Spectral analysis Nonlinear dynamics |
title_short |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
title_full |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
title_fullStr |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
title_full_unstemmed |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
title_sort |
Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients |
author |
Kunz, V.c. |
author_facet |
Kunz, V.c. Borges, E.n. Coelho, Regina Célia [UNIFESP] Gubolino, L.a. Martins, L.e.b. Silva, E. |
author_role |
author |
author2 |
Borges, E.n. Coelho, Regina Célia [UNIFESP] Gubolino, L.a. Martins, L.e.b. Silva, E. |
author2_role |
author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Carlos Departamento de Fisioterapia Núcleo de Pesquisa em Exercício Físico Universidade Metodista de Piracicaba Faculdade de Ciências da Saúde Universidade Federal de São Paulo (UNIFESP) Unidade Coronariana do Hospital dos Fornecedores de Cana de Piracicaba Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Kunz, V.c. Borges, E.n. Coelho, Regina Célia [UNIFESP] Gubolino, L.a. Martins, L.e.b. Silva, E. |
dc.subject.eng.fl_str_mv |
Myocardial infarction Heart rate variability Autonomic nervous system Spectral analysis Nonlinear dynamics |
topic |
Myocardial infarction Heart rate variability Autonomic nervous system Spectral analysis Nonlinear dynamics |
description |
The objectives of this study were to evaluate and compare the use of linear and nonlinear methods for analysis of heart rate variability (HRV) in healthy subjects and in patients after acute myocardial infarction (AMI). Heart rate (HR) was recorded for 15 min in the supine position in 10 patients with AMI taking β-blockers (aged 57 ± 9 years) and in 11 healthy subjects (aged 53 ± 4 years). HRV was analyzed in the time domain (RMSSD and RMSM), the frequency domain using low- and high-frequency bands in normalized units (nu; LFnu and HFnu) and the LF/HF ratio and approximate entropy (ApEn) were determined. There was a correlation (P < 0.05) of RMSSD, RMSM, LFnu, HFnu, and the LF/HF ratio index with the ApEn of the AMI group on the 2nd (r = 0.87, 0.65, 0.72, 0.72, and 0.64) and 7th day (r = 0.88, 0.70, 0.69, 0.69, and 0.87) and of the healthy group (r = 0.63, 0.71, 0.63, 0.63, and 0.74), respectively. The median HRV indexes of the AMI group on the 2nd and 7th day differed from the healthy group (P < 0.05): RMSSD = 10.37, 19.95, 24.81; RMSM = 23.47, 31.96, 43.79; LFnu = 0.79, 0.79, 0.62; HFnu = 0.20, 0.20, 0.37; LF/HF ratio = 3.87, 3.94, 1.65; ApEn = 1.01, 1.24, 1.31, respectively. There was agreement between the methods, suggesting that these have the same power to evaluate autonomic modulation of HR in both AMI patients and healthy subjects. AMI contributed to a reduction in cardiac signal irregularity, higher sympathetic modulation and lower vagal modulation. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-05-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:43:44Z |
dc.date.available.fl_str_mv |
2015-06-14T13:43:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 45, n. 5, p. 450-458, 2012. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/7092 http://dx.doi.org/10.1590/S0100-879X2012007500025 |
dc.identifier.issn.none.fl_str_mv |
0100-879X |
dc.identifier.file.none.fl_str_mv |
S0100-879X2012000500011.pdf |
dc.identifier.scielo.none.fl_str_mv |
S0100-879X2012000500011 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0100-879X2012007500025 |
dc.identifier.wos.none.fl_str_mv |
WOS:000303940200011 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 45, n. 5, p. 450-458, 2012. 0100-879X S0100-879X2012000500011.pdf S0100-879X2012000500011 10.1590/S0100-879X2012007500025 WOS:000303940200011 |
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http://repositorio.unifesp.br/handle/11600/7092 http://dx.doi.org/10.1590/S0100-879X2012007500025 |
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eng |
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Brazilian Journal of Medical and Biological Research |
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info:eu-repo/semantics/openAccess |
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openAccess |
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450-458 |
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Associação Brasileira de Divulgação Científica |
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Associação Brasileira de Divulgação Científica |
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