Acoustic rhinometry in nasal provocation tests in children and adolescents
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
dARK ID: | ark:/48912/001300000bvbt |
Texto Completo: | http://dx.doi.org/10.18176/jiaci.0036 http://repositorio.unifesp.br/handle/11600/49461 |
Resumo: | Objectives: To standardize acoustic rhinometry (AR) in nasal provocation tests (NPTs) with histamine in children and adolescents. Patients and Methods: We performed a cross-sectional validation to compare AR with anterior active rhinomanometry (AAR) during histamine NPT in 20 children and adolescents with persistent allergic rhinitis and 20 controls. Changes in total nasal resistance (AAR) were compared with changes in nasal volume in the first 5 cm (V5). Results: Compared with controls, patients with rhinitis had significantly higher mean total nasal resistance (0.34 Pa/cm(3)/s vs 0.21 Pa/cm(3)/s |
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Repositório Institucional da UNIFESP |
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3465 |
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Acoustic rhinometry in nasal provocation tests in children and adolescentsRhinitisNasal Provocation TestsHistamineAcoustic RhinometryRhinomanometryNasal CavityAirway ResistanceAllergic RhinitisChallengeResistancePatencyObjectives: To standardize acoustic rhinometry (AR) in nasal provocation tests (NPTs) with histamine in children and adolescents. Patients and Methods: We performed a cross-sectional validation to compare AR with anterior active rhinomanometry (AAR) during histamine NPT in 20 children and adolescents with persistent allergic rhinitis and 20 controls. Changes in total nasal resistance (AAR) were compared with changes in nasal volume in the first 5 cm (V5). Results: Compared with controls, patients with rhinitis had significantly higher mean total nasal resistance (0.34 Pa/cm(3)/s vs 0.21 Pa/cm(3)/sP=.01) and lower mean V5 values (8.20 cm(3) vs 9.24 cm(3)P=.04) at baseline. The mean histamine concentration necessary to increase total nasal resistance by at least 100% was significantly lower in the rhinitis group than in the control group (0.72 mg/mL vs 2.4 mg/mLP<.001). At the end of the NPT a mean increase of 126% in total nasal resistance and a mean decrease of 24.3% in V5 were observed in the rhinitis group. When compared with the AAR criteria, the highest sensitivity and specificity values were observed for a cutoff represented by a 19%-21% drop in V5. Conclusions: We found AR to be a feasible and sensitive tool for monitoring nasal response in children and adolescents undergoing histamine NPT. The best AR cutoff for ending the NPT was a 19%-21% drop in V5.Division of Allergy and Clinical Immunology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), São Paulo, BrazilDivision of Allergy and Clinical Immunology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), Rua Otonis 725, BR-04025002 Sao Paulo, SP, Brazil.Web of ScienceFAPESPCAPESThis study was funded FAPESP and CAPES.Hindawi Ltd2019-01-21T10:29:54Z2019-01-21T10:29:54Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion156-160http://dx.doi.org/10.18176/jiaci.0036Journal Of Investigational Allergology And Clinical Immunology. Barcelona, v. 26, n. 3, p. 156-160, 2016.10.18176/jiaci.00361018-9068http://repositorio.unifesp.br/handle/11600/49461WOS:000379704800002ark:/48912/001300000bvbtengJournal Of Investigational Allergology And Clinical Immunologyinfo:eu-repo/semantics/openAccessWandalsen, G. F. [UNIFESP]Mendes, A. L. [UNIFESP]Matsumoto, F. [UNIFESP]Sole, D. [UNIFESP]reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2022-02-07T20:58:48Zoai:repositorio.unifesp.br/:11600/49461Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:09:55.960352Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
title |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
spellingShingle |
Acoustic rhinometry in nasal provocation tests in children and adolescents Wandalsen, G. F. [UNIFESP] Rhinitis Nasal Provocation Tests Histamine Acoustic Rhinometry Rhinomanometry Nasal Cavity Airway ResistanceAllergic Rhinitis Challenge Resistance Patency |
title_short |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
title_full |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
title_fullStr |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
title_full_unstemmed |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
title_sort |
Acoustic rhinometry in nasal provocation tests in children and adolescents |
author |
Wandalsen, G. F. [UNIFESP] |
author_facet |
Wandalsen, G. F. [UNIFESP] Mendes, A. L. [UNIFESP] Matsumoto, F. [UNIFESP] Sole, D. [UNIFESP] |
author_role |
author |
author2 |
Mendes, A. L. [UNIFESP] Matsumoto, F. [UNIFESP] Sole, D. [UNIFESP] |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Wandalsen, G. F. [UNIFESP] Mendes, A. L. [UNIFESP] Matsumoto, F. [UNIFESP] Sole, D. [UNIFESP] |
dc.subject.por.fl_str_mv |
Rhinitis Nasal Provocation Tests Histamine Acoustic Rhinometry Rhinomanometry Nasal Cavity Airway ResistanceAllergic Rhinitis Challenge Resistance Patency |
topic |
Rhinitis Nasal Provocation Tests Histamine Acoustic Rhinometry Rhinomanometry Nasal Cavity Airway ResistanceAllergic Rhinitis Challenge Resistance Patency |
description |
Objectives: To standardize acoustic rhinometry (AR) in nasal provocation tests (NPTs) with histamine in children and adolescents. Patients and Methods: We performed a cross-sectional validation to compare AR with anterior active rhinomanometry (AAR) during histamine NPT in 20 children and adolescents with persistent allergic rhinitis and 20 controls. Changes in total nasal resistance (AAR) were compared with changes in nasal volume in the first 5 cm (V5). Results: Compared with controls, patients with rhinitis had significantly higher mean total nasal resistance (0.34 Pa/cm(3)/s vs 0.21 Pa/cm(3)/s |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016 2019-01-21T10:29:54Z 2019-01-21T10:29:54Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.18176/jiaci.0036 Journal Of Investigational Allergology And Clinical Immunology. Barcelona, v. 26, n. 3, p. 156-160, 2016. 10.18176/jiaci.0036 1018-9068 http://repositorio.unifesp.br/handle/11600/49461 WOS:000379704800002 |
dc.identifier.dark.fl_str_mv |
ark:/48912/001300000bvbt |
url |
http://dx.doi.org/10.18176/jiaci.0036 http://repositorio.unifesp.br/handle/11600/49461 |
identifier_str_mv |
Journal Of Investigational Allergology And Clinical Immunology. Barcelona, v. 26, n. 3, p. 156-160, 2016. 10.18176/jiaci.0036 1018-9068 WOS:000379704800002 ark:/48912/001300000bvbt |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal Of Investigational Allergology And Clinical Immunology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
156-160 |
dc.publisher.none.fl_str_mv |
Hindawi Ltd |
publisher.none.fl_str_mv |
Hindawi Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1818602440157560832 |