Acoustic rhinometry in nasal provocation tests in children and adolescents

Detalhes bibliográficos
Autor(a) principal: Wandalsen, G. F. [UNIFESP]
Data de Publicação: 2016
Outros Autores: Mendes, A. L. [UNIFESP], Matsumoto, F. [UNIFESP], Sole, D. [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
dARK ID: ark:/48912/001300000bvbt
Texto Completo: http://dx.doi.org/10.18176/jiaci.0036
http://repositorio.unifesp.br/handle/11600/49461
Resumo: Objectives: To standardize acoustic rhinometry (AR) in nasal provocation tests (NPTs) with histamine in children and adolescents. Patients and Methods: We performed a cross-sectional validation to compare AR with anterior active rhinomanometry (AAR) during histamine NPT in 20 children and adolescents with persistent allergic rhinitis and 20 controls. Changes in total nasal resistance (AAR) were compared with changes in nasal volume in the first 5 cm (V5). Results: Compared with controls, patients with rhinitis had significantly higher mean total nasal resistance (0.34 Pa/cm(3)/s vs 0.21 Pa/cm(3)/s
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spelling Acoustic rhinometry in nasal provocation tests in children and adolescentsRhinitisNasal Provocation TestsHistamineAcoustic RhinometryRhinomanometryNasal CavityAirway ResistanceAllergic RhinitisChallengeResistancePatencyObjectives: To standardize acoustic rhinometry (AR) in nasal provocation tests (NPTs) with histamine in children and adolescents. Patients and Methods: We performed a cross-sectional validation to compare AR with anterior active rhinomanometry (AAR) during histamine NPT in 20 children and adolescents with persistent allergic rhinitis and 20 controls. Changes in total nasal resistance (AAR) were compared with changes in nasal volume in the first 5 cm (V5). Results: Compared with controls, patients with rhinitis had significantly higher mean total nasal resistance (0.34 Pa/cm(3)/s vs 0.21 Pa/cm(3)/sP=.01) and lower mean V5 values (8.20 cm(3) vs 9.24 cm(3)P=.04) at baseline. The mean histamine concentration necessary to increase total nasal resistance by at least 100% was significantly lower in the rhinitis group than in the control group (0.72 mg/mL vs 2.4 mg/mLP<.001). At the end of the NPT a mean increase of 126% in total nasal resistance and a mean decrease of 24.3% in V5 were observed in the rhinitis group. When compared with the AAR criteria, the highest sensitivity and specificity values were observed for a cutoff represented by a 19%-21% drop in V5. Conclusions: We found AR to be a feasible and sensitive tool for monitoring nasal response in children and adolescents undergoing histamine NPT. The best AR cutoff for ending the NPT was a 19%-21% drop in V5.Division of Allergy and Clinical Immunology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), São Paulo, BrazilDivision of Allergy and Clinical Immunology, Department of Pediatrics, Federal University of São Paulo (UNIFESP), Rua Otonis 725, BR-04025002 Sao Paulo, SP, Brazil.Web of ScienceFAPESPCAPESThis study was funded FAPESP and CAPES.Hindawi Ltd2019-01-21T10:29:54Z2019-01-21T10:29:54Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion156-160http://dx.doi.org/10.18176/jiaci.0036Journal Of Investigational Allergology And Clinical Immunology. Barcelona, v. 26, n. 3, p. 156-160, 2016.10.18176/jiaci.00361018-9068http://repositorio.unifesp.br/handle/11600/49461WOS:000379704800002ark:/48912/001300000bvbtengJournal Of Investigational Allergology And Clinical Immunologyinfo:eu-repo/semantics/openAccessWandalsen, G. F. [UNIFESP]Mendes, A. L. [UNIFESP]Matsumoto, F. [UNIFESP]Sole, D. [UNIFESP]reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2022-02-07T20:58:48Zoai:repositorio.unifesp.br/:11600/49461Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:09:55.960352Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Acoustic rhinometry in nasal provocation tests in children and adolescents
title Acoustic rhinometry in nasal provocation tests in children and adolescents
spellingShingle Acoustic rhinometry in nasal provocation tests in children and adolescents
Wandalsen, G. F. [UNIFESP]
Rhinitis
Nasal Provocation Tests
Histamine
Acoustic Rhinometry
Rhinomanometry
Nasal Cavity
Airway ResistanceAllergic Rhinitis
Challenge
Resistance
Patency
title_short Acoustic rhinometry in nasal provocation tests in children and adolescents
title_full Acoustic rhinometry in nasal provocation tests in children and adolescents
title_fullStr Acoustic rhinometry in nasal provocation tests in children and adolescents
title_full_unstemmed Acoustic rhinometry in nasal provocation tests in children and adolescents
title_sort Acoustic rhinometry in nasal provocation tests in children and adolescents
author Wandalsen, G. F. [UNIFESP]
author_facet Wandalsen, G. F. [UNIFESP]
Mendes, A. L. [UNIFESP]
Matsumoto, F. [UNIFESP]
Sole, D. [UNIFESP]
author_role author
author2 Mendes, A. L. [UNIFESP]
Matsumoto, F. [UNIFESP]
Sole, D. [UNIFESP]
author2_role author
author
author
dc.contributor.author.fl_str_mv Wandalsen, G. F. [UNIFESP]
Mendes, A. L. [UNIFESP]
Matsumoto, F. [UNIFESP]
Sole, D. [UNIFESP]
dc.subject.por.fl_str_mv Rhinitis
Nasal Provocation Tests
Histamine
Acoustic Rhinometry
Rhinomanometry
Nasal Cavity
Airway ResistanceAllergic Rhinitis
Challenge
Resistance
Patency
topic Rhinitis
Nasal Provocation Tests
Histamine
Acoustic Rhinometry
Rhinomanometry
Nasal Cavity
Airway ResistanceAllergic Rhinitis
Challenge
Resistance
Patency
description Objectives: To standardize acoustic rhinometry (AR) in nasal provocation tests (NPTs) with histamine in children and adolescents. Patients and Methods: We performed a cross-sectional validation to compare AR with anterior active rhinomanometry (AAR) during histamine NPT in 20 children and adolescents with persistent allergic rhinitis and 20 controls. Changes in total nasal resistance (AAR) were compared with changes in nasal volume in the first 5 cm (V5). Results: Compared with controls, patients with rhinitis had significantly higher mean total nasal resistance (0.34 Pa/cm(3)/s vs 0.21 Pa/cm(3)/s
publishDate 2016
dc.date.none.fl_str_mv 2016
2019-01-21T10:29:54Z
2019-01-21T10:29:54Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.18176/jiaci.0036
Journal Of Investigational Allergology And Clinical Immunology. Barcelona, v. 26, n. 3, p. 156-160, 2016.
10.18176/jiaci.0036
1018-9068
http://repositorio.unifesp.br/handle/11600/49461
WOS:000379704800002
dc.identifier.dark.fl_str_mv ark:/48912/001300000bvbt
url http://dx.doi.org/10.18176/jiaci.0036
http://repositorio.unifesp.br/handle/11600/49461
identifier_str_mv Journal Of Investigational Allergology And Clinical Immunology. Barcelona, v. 26, n. 3, p. 156-160, 2016.
10.18176/jiaci.0036
1018-9068
WOS:000379704800002
ark:/48912/001300000bvbt
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal Of Investigational Allergology And Clinical Immunology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 156-160
dc.publisher.none.fl_str_mv Hindawi Ltd
publisher.none.fl_str_mv Hindawi Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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