MYC and gastric adenocarcinoma carcinogenesis

Detalhes bibliográficos
Autor(a) principal: Calcagno, Danielle Queiroz
Data de Publicação: 2008
Outros Autores: Leal, Mariana Ferreira [UNIFESP], Assumpcao, Paulo Pimentel, Smith, Marilia de Arruda Cardoso [UNIFESP], Burbano, Rommel Rodriguez
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.3748/wjg.14.5962
http://repositorio.unifesp.br/handle/11600/30971
Resumo: MYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion, metabolism, ribosome biogenesis, protein synthesis, and mitochondrial function. It has been described as a key element of several carcinogenesis processes in humans. Many studies have shown an association between MYC deregulation and gastric cancer. MYC deregulation is also seen in gastric preneoplastic lesions and thus it may have a role in early gastric carcinogenesis. Several studies have suggested that amplification is the main mechanism of MYC deregulation in gastric cancer. in the present review, we focus on the deregulation of the MYC oncogene in gastric adenocarcinorna carcinogenesis, including its association with Helicobacterpylori (Hpylorl) and clinical applications. (c) 2008 the WIG Press. All rights reserved.
id UFSP_3fb607caf7b00c9ede0930b088a04070
oai_identifier_str oai:repositorio.unifesp.br/:11600/30971
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling MYC and gastric adenocarcinoma carcinogenesisMYCGastric adenocarcinomaGastric preneoplastic lesionsGastric carcinogenesisHelicobacter pyloriMYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion, metabolism, ribosome biogenesis, protein synthesis, and mitochondrial function. It has been described as a key element of several carcinogenesis processes in humans. Many studies have shown an association between MYC deregulation and gastric cancer. MYC deregulation is also seen in gastric preneoplastic lesions and thus it may have a role in early gastric carcinogenesis. Several studies have suggested that amplification is the main mechanism of MYC deregulation in gastric cancer. in the present review, we focus on the deregulation of the MYC oncogene in gastric adenocarcinorna carcinogenesis, including its association with Helicobacterpylori (Hpylorl) and clinical applications. (c) 2008 the WIG Press. All rights reserved.Universidade Federal de São Paulo, Dept Morphol & Genet, Div Genet, BR-04023900 São Paulo, BrazilFed Univ Para, Joao de Barros Barreto Univ Hosp, BR-66073000 Belem, Para, BrazilFed Univ Para, Dept Biol, Lab Citogenet Humana, Inst Ciencias Biol, BR-66075900 Belem, Para, BrazilUniversidade Federal de São Paulo, Dept Morphol & Genet, Div Genet, BR-04023900 São Paulo, BrazilWeb of ScienceConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Baishideng Publ Grp Co LtdUniversidade Federal de São Paulo (UNIFESP)Fed Univ ParaCalcagno, Danielle QueirozLeal, Mariana Ferreira [UNIFESP]Assumpcao, Paulo PimentelSmith, Marilia de Arruda Cardoso [UNIFESP]Burbano, Rommel Rodriguez2016-01-24T13:51:46Z2016-01-24T13:51:46Z2008-10-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion5962-5968http://dx.doi.org/10.3748/wjg.14.5962World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 14, n. 39, p. 5962-5968, 2008.10.3748/wjg.14.59621007-9327http://repositorio.unifesp.br/handle/11600/30971WOS:000260384100002engWorld Journal of Gastroenterologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2023-03-27T13:13:00Zoai:repositorio.unifesp.br/:11600/30971Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652023-03-27T13:13Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv MYC and gastric adenocarcinoma carcinogenesis
title MYC and gastric adenocarcinoma carcinogenesis
spellingShingle MYC and gastric adenocarcinoma carcinogenesis
Calcagno, Danielle Queiroz
MYC
Gastric adenocarcinoma
Gastric preneoplastic lesions
Gastric carcinogenesis
Helicobacter pylori
title_short MYC and gastric adenocarcinoma carcinogenesis
title_full MYC and gastric adenocarcinoma carcinogenesis
title_fullStr MYC and gastric adenocarcinoma carcinogenesis
title_full_unstemmed MYC and gastric adenocarcinoma carcinogenesis
title_sort MYC and gastric adenocarcinoma carcinogenesis
author Calcagno, Danielle Queiroz
author_facet Calcagno, Danielle Queiroz
Leal, Mariana Ferreira [UNIFESP]
Assumpcao, Paulo Pimentel
Smith, Marilia de Arruda Cardoso [UNIFESP]
Burbano, Rommel Rodriguez
author_role author
author2 Leal, Mariana Ferreira [UNIFESP]
Assumpcao, Paulo Pimentel
Smith, Marilia de Arruda Cardoso [UNIFESP]
Burbano, Rommel Rodriguez
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Fed Univ Para
dc.contributor.author.fl_str_mv Calcagno, Danielle Queiroz
Leal, Mariana Ferreira [UNIFESP]
Assumpcao, Paulo Pimentel
Smith, Marilia de Arruda Cardoso [UNIFESP]
Burbano, Rommel Rodriguez
dc.subject.por.fl_str_mv MYC
Gastric adenocarcinoma
Gastric preneoplastic lesions
Gastric carcinogenesis
Helicobacter pylori
topic MYC
Gastric adenocarcinoma
Gastric preneoplastic lesions
Gastric carcinogenesis
Helicobacter pylori
description MYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion, metabolism, ribosome biogenesis, protein synthesis, and mitochondrial function. It has been described as a key element of several carcinogenesis processes in humans. Many studies have shown an association between MYC deregulation and gastric cancer. MYC deregulation is also seen in gastric preneoplastic lesions and thus it may have a role in early gastric carcinogenesis. Several studies have suggested that amplification is the main mechanism of MYC deregulation in gastric cancer. in the present review, we focus on the deregulation of the MYC oncogene in gastric adenocarcinorna carcinogenesis, including its association with Helicobacterpylori (Hpylorl) and clinical applications. (c) 2008 the WIG Press. All rights reserved.
publishDate 2008
dc.date.none.fl_str_mv 2008-10-21
2016-01-24T13:51:46Z
2016-01-24T13:51:46Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3748/wjg.14.5962
World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 14, n. 39, p. 5962-5968, 2008.
10.3748/wjg.14.5962
1007-9327
http://repositorio.unifesp.br/handle/11600/30971
WOS:000260384100002
url http://dx.doi.org/10.3748/wjg.14.5962
http://repositorio.unifesp.br/handle/11600/30971
identifier_str_mv World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 14, n. 39, p. 5962-5968, 2008.
10.3748/wjg.14.5962
1007-9327
WOS:000260384100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv World Journal of Gastroenterology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 5962-5968
dc.publisher.none.fl_str_mv Baishideng Publ Grp Co Ltd
publisher.none.fl_str_mv Baishideng Publ Grp Co Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268399960719360

Registros relacionados