Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
Autor(a) principal: | |
---|---|
Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/32269 http://dx.doi.org/10.3748/wjg.v16.i6.728 |
Resumo: | AIM: To assess the feasibility of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) using a poloxamer.METHODS: in this prospective evaluation, six Yorkshire pigs underwent EUS-guided CPN. Three received an injection of 10 mL of 0.25% Lidocaine plus methylene blue (group 1) and three received an injection of 10 mL of 0.25% Lidocaine plus blue colored poloxamer (PS137-25) (group 2). Necropsy was performed immediately after the animals were sacrificed. the abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS: EUS-guided CPN was successfully performed in all 6 pigs without immediate complication. Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1. the blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta, in the exact location of the celiac plexus in group 2.CONCLUSION: EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible. the presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. (C) 2010 Baishideng. All rights reserved. |
id |
UFSP_6ad664b271a87639be3819b96ca32d0c |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br:11600/32269 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Obstein, Keith L.Martins, Fernanda P. [UNIFESP]Fernandez-Esparrach, GloriaThompson, Christopher C.Brigham & Womens HospUniversidade Federal de São Paulo (UNIFESP)Hosp Clin Barcelona2016-01-24T13:59:19Z2016-01-24T13:59:19Z2010-02-14World Journal of Gastroenterology. Beijing: W J G Press, v. 16, n. 6, p. 728-731, 2010.1007-9327http://repositorio.unifesp.br/handle/11600/32269http://dx.doi.org/10.3748/wjg.v16.i6.72810.3748/wjg.v16.i6.728WOS:000274459200010AIM: To assess the feasibility of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) using a poloxamer.METHODS: in this prospective evaluation, six Yorkshire pigs underwent EUS-guided CPN. Three received an injection of 10 mL of 0.25% Lidocaine plus methylene blue (group 1) and three received an injection of 10 mL of 0.25% Lidocaine plus blue colored poloxamer (PS137-25) (group 2). Necropsy was performed immediately after the animals were sacrificed. the abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS: EUS-guided CPN was successfully performed in all 6 pigs without immediate complication. Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1. the blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta, in the exact location of the celiac plexus in group 2.CONCLUSION: EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible. the presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. (C) 2010 Baishideng. All rights reserved.Generalitat de Catalunya (AGAUR)Brigham & Womens Hosp, Div Gastroenterol, Boston, MA 02115 USAUniversidade Federal de São Paulo, BR-04023062 São Paulo, BrazilHosp Clin Barcelona, Dept Gastroenterol, Endoscopy Unit, E-08036 Barcelona, SpainUniversidade Federal de São Paulo, BR-04023062 São Paulo, BrazilGeneralitat de Catalunya (AGAUR): BE-100022Web of Science728-731engW J G PressWorld Journal of GastroenterologyCeliac plexus neurolysisCeliac plexus blockadeEndoscopic ultrasoundPolymerEndoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymerinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/322692022-09-27 14:37:31.529metadata only accessoai:repositorio.unifesp.br:11600/32269Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-09-27T17:37:31Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
title |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
spellingShingle |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer Obstein, Keith L. Celiac plexus neurolysis Celiac plexus blockade Endoscopic ultrasound Polymer |
title_short |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
title_full |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
title_fullStr |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
title_full_unstemmed |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
title_sort |
Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer |
author |
Obstein, Keith L. |
author_facet |
Obstein, Keith L. Martins, Fernanda P. [UNIFESP] Fernandez-Esparrach, Gloria Thompson, Christopher C. |
author_role |
author |
author2 |
Martins, Fernanda P. [UNIFESP] Fernandez-Esparrach, Gloria Thompson, Christopher C. |
author2_role |
author author author |
dc.contributor.institution.none.fl_str_mv |
Brigham & Womens Hosp Universidade Federal de São Paulo (UNIFESP) Hosp Clin Barcelona |
dc.contributor.author.fl_str_mv |
Obstein, Keith L. Martins, Fernanda P. [UNIFESP] Fernandez-Esparrach, Gloria Thompson, Christopher C. |
dc.subject.eng.fl_str_mv |
Celiac plexus neurolysis Celiac plexus blockade Endoscopic ultrasound Polymer |
topic |
Celiac plexus neurolysis Celiac plexus blockade Endoscopic ultrasound Polymer |
description |
AIM: To assess the feasibility of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) using a poloxamer.METHODS: in this prospective evaluation, six Yorkshire pigs underwent EUS-guided CPN. Three received an injection of 10 mL of 0.25% Lidocaine plus methylene blue (group 1) and three received an injection of 10 mL of 0.25% Lidocaine plus blue colored poloxamer (PS137-25) (group 2). Necropsy was performed immediately after the animals were sacrificed. the abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS: EUS-guided CPN was successfully performed in all 6 pigs without immediate complication. Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1. the blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta, in the exact location of the celiac plexus in group 2.CONCLUSION: EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible. the presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. (C) 2010 Baishideng. All rights reserved. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010-02-14 |
dc.date.accessioned.fl_str_mv |
2016-01-24T13:59:19Z |
dc.date.available.fl_str_mv |
2016-01-24T13:59:19Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
World Journal of Gastroenterology. Beijing: W J G Press, v. 16, n. 6, p. 728-731, 2010. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/32269 http://dx.doi.org/10.3748/wjg.v16.i6.728 |
dc.identifier.issn.none.fl_str_mv |
1007-9327 |
dc.identifier.doi.none.fl_str_mv |
10.3748/wjg.v16.i6.728 |
dc.identifier.wos.none.fl_str_mv |
WOS:000274459200010 |
identifier_str_mv |
World Journal of Gastroenterology. Beijing: W J G Press, v. 16, n. 6, p. 728-731, 2010. 1007-9327 10.3748/wjg.v16.i6.728 WOS:000274459200010 |
url |
http://repositorio.unifesp.br/handle/11600/32269 http://dx.doi.org/10.3748/wjg.v16.i6.728 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
World Journal of Gastroenterology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
728-731 |
dc.publisher.none.fl_str_mv |
W J G Press |
publisher.none.fl_str_mv |
W J G Press |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
_version_ |
1802764177461215232 |