Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer

Detalhes bibliográficos
Autor(a) principal: Obstein, Keith L.
Data de Publicação: 2010
Outros Autores: Martins, Fernanda P. [UNIFESP], Fernandez-Esparrach, Gloria, Thompson, Christopher C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://repositorio.unifesp.br/handle/11600/32269
http://dx.doi.org/10.3748/wjg.v16.i6.728
Resumo: AIM: To assess the feasibility of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) using a poloxamer.METHODS: in this prospective evaluation, six Yorkshire pigs underwent EUS-guided CPN. Three received an injection of 10 mL of 0.25% Lidocaine plus methylene blue (group 1) and three received an injection of 10 mL of 0.25% Lidocaine plus blue colored poloxamer (PS137-25) (group 2). Necropsy was performed immediately after the animals were sacrificed. the abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS: EUS-guided CPN was successfully performed in all 6 pigs without immediate complication. Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1. the blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta, in the exact location of the celiac plexus in group 2.CONCLUSION: EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible. the presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. (C) 2010 Baishideng. All rights reserved.
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spelling Obstein, Keith L.Martins, Fernanda P. [UNIFESP]Fernandez-Esparrach, GloriaThompson, Christopher C.Brigham & Womens HospUniversidade Federal de São Paulo (UNIFESP)Hosp Clin Barcelona2016-01-24T13:59:19Z2016-01-24T13:59:19Z2010-02-14World Journal of Gastroenterology. Beijing: W J G Press, v. 16, n. 6, p. 728-731, 2010.1007-9327http://repositorio.unifesp.br/handle/11600/32269http://dx.doi.org/10.3748/wjg.v16.i6.72810.3748/wjg.v16.i6.728WOS:000274459200010AIM: To assess the feasibility of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) using a poloxamer.METHODS: in this prospective evaluation, six Yorkshire pigs underwent EUS-guided CPN. Three received an injection of 10 mL of 0.25% Lidocaine plus methylene blue (group 1) and three received an injection of 10 mL of 0.25% Lidocaine plus blue colored poloxamer (PS137-25) (group 2). Necropsy was performed immediately after the animals were sacrificed. the abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS: EUS-guided CPN was successfully performed in all 6 pigs without immediate complication. Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1. the blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta, in the exact location of the celiac plexus in group 2.CONCLUSION: EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible. the presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. (C) 2010 Baishideng. All rights reserved.Generalitat de Catalunya (AGAUR)Brigham & Womens Hosp, Div Gastroenterol, Boston, MA 02115 USAUniversidade Federal de São Paulo, BR-04023062 São Paulo, BrazilHosp Clin Barcelona, Dept Gastroenterol, Endoscopy Unit, E-08036 Barcelona, SpainUniversidade Federal de São Paulo, BR-04023062 São Paulo, BrazilGeneralitat de Catalunya (AGAUR): BE-100022Web of Science728-731engW J G PressWorld Journal of GastroenterologyCeliac plexus neurolysisCeliac plexus blockadeEndoscopic ultrasoundPolymerEndoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymerinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/322692022-09-27 14:37:31.529metadata only accessoai:repositorio.unifesp.br:11600/32269Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-09-27T17:37:31Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.en.fl_str_mv Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
title Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
spellingShingle Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
Obstein, Keith L.
Celiac plexus neurolysis
Celiac plexus blockade
Endoscopic ultrasound
Polymer
title_short Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
title_full Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
title_fullStr Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
title_full_unstemmed Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
title_sort Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer
author Obstein, Keith L.
author_facet Obstein, Keith L.
Martins, Fernanda P. [UNIFESP]
Fernandez-Esparrach, Gloria
Thompson, Christopher C.
author_role author
author2 Martins, Fernanda P. [UNIFESP]
Fernandez-Esparrach, Gloria
Thompson, Christopher C.
author2_role author
author
author
dc.contributor.institution.none.fl_str_mv Brigham & Womens Hosp
Universidade Federal de São Paulo (UNIFESP)
Hosp Clin Barcelona
dc.contributor.author.fl_str_mv Obstein, Keith L.
Martins, Fernanda P. [UNIFESP]
Fernandez-Esparrach, Gloria
Thompson, Christopher C.
dc.subject.eng.fl_str_mv Celiac plexus neurolysis
Celiac plexus blockade
Endoscopic ultrasound
Polymer
topic Celiac plexus neurolysis
Celiac plexus blockade
Endoscopic ultrasound
Polymer
description AIM: To assess the feasibility of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN) using a poloxamer.METHODS: in this prospective evaluation, six Yorkshire pigs underwent EUS-guided CPN. Three received an injection of 10 mL of 0.25% Lidocaine plus methylene blue (group 1) and three received an injection of 10 mL of 0.25% Lidocaine plus blue colored poloxamer (PS137-25) (group 2). Necropsy was performed immediately after the animals were sacrificed. the abdominal and pelvic cavities were examined for the presence of methylene blue and the blue colored poloxamer.RESULTS: EUS-guided CPN was successfully performed in all 6 pigs without immediate complication. Methylene blue was identified throughout the peritoneal and retroperitoneal cavity in group 1. the blue colored poloxamer was found in the retroperitoneal cavity immediately adjacent to the aorta, in the exact location of the celiac plexus in group 2.CONCLUSION: EUS-guided CPN using a reverse phase polymer in a non-survival porcine model was technically feasible. the presence of a poloxamer gel at the site of the celiac plexus at necropsy indicates a precise delivery of the neurolytic agent. (C) 2010 Baishideng. All rights reserved.
publishDate 2010
dc.date.issued.fl_str_mv 2010-02-14
dc.date.accessioned.fl_str_mv 2016-01-24T13:59:19Z
dc.date.available.fl_str_mv 2016-01-24T13:59:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv World Journal of Gastroenterology. Beijing: W J G Press, v. 16, n. 6, p. 728-731, 2010.
dc.identifier.uri.fl_str_mv http://repositorio.unifesp.br/handle/11600/32269
http://dx.doi.org/10.3748/wjg.v16.i6.728
dc.identifier.issn.none.fl_str_mv 1007-9327
dc.identifier.doi.none.fl_str_mv 10.3748/wjg.v16.i6.728
dc.identifier.wos.none.fl_str_mv WOS:000274459200010
identifier_str_mv World Journal of Gastroenterology. Beijing: W J G Press, v. 16, n. 6, p. 728-731, 2010.
1007-9327
10.3748/wjg.v16.i6.728
WOS:000274459200010
url http://repositorio.unifesp.br/handle/11600/32269
http://dx.doi.org/10.3748/wjg.v16.i6.728
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv World Journal of Gastroenterology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 728-731
dc.publisher.none.fl_str_mv W J G Press
publisher.none.fl_str_mv W J G Press
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv
_version_ 1802764177461215232

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