Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae

Detalhes bibliográficos
Autor(a) principal: Pelizon, Ana Claudia
Data de Publicação: 2005
Outros Autores: Kaneno, Ramon, Soares, Angela Maria Victoriano de Campos [UNIFESP], Meira, Domingos Alves [UNIFESP], Sartori, Alexandrina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://www.biomed.cas.cz/physiolres/pdf/54/54_557.pdf
http://repositorio.unifesp.br/handle/11600/45102
Resumo: In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
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spelling Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiaebeta-glucanIL-12TNF-alphaNK activityfungicidal activityIn this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.Univ Fed Sao Paulo, Inst Biosci, Dept Microbiol & Immunol, Sao Paulo, BrazilUniv Fed Sao Paulo, Fac Med, Dept Trop Dis & Diagnosis Image, Sao Paulo, BrazilUniv Fed Sao Paulo, Inst Biosci, Dept Microbiol & Immunol, Sao Paulo, BrazilUniv Fed Sao Paulo, Fac Med, Dept Trop Dis & Diagnosis Image, Sao Paulo, BrazilWeb of ScienceAcad Sciences Czech Republic, Inst PhysiologyUniversidade Federal de São Paulo (UNIFESP)Pelizon, Ana ClaudiaKaneno, RamonSoares, Angela Maria Victoriano de Campos [UNIFESP]Meira, Domingos Alves [UNIFESP]Sartori, Alexandrina2018-06-18T11:27:05Z2018-06-18T11:27:05Z2005-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion557-564http://www.biomed.cas.cz/physiolres/pdf/54/54_557.pdfPhysiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.0862-8408http://repositorio.unifesp.br/handle/11600/45102WOS:000233101100012engPhysiological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-05-02T13:59:15Zoai:repositorio.unifesp.br/:11600/45102Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-05-02T13:59:15Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
spellingShingle Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
Pelizon, Ana Claudia
beta-glucan
IL-12
TNF-alpha
NK activity
fungicidal activity
title_short Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_full Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_fullStr Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_full_unstemmed Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_sort Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
author Pelizon, Ana Claudia
author_facet Pelizon, Ana Claudia
Kaneno, Ramon
Soares, Angela Maria Victoriano de Campos [UNIFESP]
Meira, Domingos Alves [UNIFESP]
Sartori, Alexandrina
author_role author
author2 Kaneno, Ramon
Soares, Angela Maria Victoriano de Campos [UNIFESP]
Meira, Domingos Alves [UNIFESP]
Sartori, Alexandrina
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Pelizon, Ana Claudia
Kaneno, Ramon
Soares, Angela Maria Victoriano de Campos [UNIFESP]
Meira, Domingos Alves [UNIFESP]
Sartori, Alexandrina
dc.subject.por.fl_str_mv beta-glucan
IL-12
TNF-alpha
NK activity
fungicidal activity
topic beta-glucan
IL-12
TNF-alpha
NK activity
fungicidal activity
description In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
publishDate 2005
dc.date.none.fl_str_mv 2005-01-01
2018-06-18T11:27:05Z
2018-06-18T11:27:05Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.biomed.cas.cz/physiolres/pdf/54/54_557.pdf
Physiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.
0862-8408
http://repositorio.unifesp.br/handle/11600/45102
WOS:000233101100012
url http://www.biomed.cas.cz/physiolres/pdf/54/54_557.pdf
http://repositorio.unifesp.br/handle/11600/45102
identifier_str_mv Physiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.
0862-8408
WOS:000233101100012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Physiological Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 557-564
dc.publisher.none.fl_str_mv Acad Sciences Czech Republic, Inst Physiology
publisher.none.fl_str_mv Acad Sciences Czech Republic, Inst Physiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268288498139136

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