Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae

Detalhes bibliográficos
Autor(a) principal: Pelizon, A. C.
Data de Publicação: 2005
Outros Autores: Kaneno, Ramon [UNESP], Soares, AMVC, Meira, D. A., Sartori, A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm
http://hdl.handle.net/11449/33989
Resumo: In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
id UNSP_5f772fc41f961b756f81a52ff9275a4c
oai_identifier_str oai:repositorio.unesp.br:11449/33989
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiaebeta-glucanIL-12TNF-alphaNK activityfungicidal activityIn this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.Univ Fed São Paulo, Inst Biosci, Dept Microbiol & Immunol, São Paulo, BrazilUniv Fed São Paulo, Fac Med, Dept Trop Dis & Diagnosis Image, São Paulo, BrazilAcad Sciences Czech Republic, Inst PhysiologyUniversidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Pelizon, A. C.Kaneno, Ramon [UNESP]Soares, AMVCMeira, D. A.Sartori, A.2014-05-20T15:23:09Z2014-05-20T15:23:09Z2005-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article557-564http://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htmPhysiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.0862-8408http://hdl.handle.net/11449/33989WOS:000233101100012884583555063780949775724161295270000-0002-4292-3298Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPhysiological Research1.3240,568info:eu-repo/semantics/openAccess2021-10-23T11:55:37Zoai:repositorio.unesp.br:11449/33989Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T11:55:37Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
spellingShingle Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
Pelizon, A. C.
beta-glucan
IL-12
TNF-alpha
NK activity
fungicidal activity
title_short Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_full Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_fullStr Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_full_unstemmed Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
title_sort Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
author Pelizon, A. C.
author_facet Pelizon, A. C.
Kaneno, Ramon [UNESP]
Soares, AMVC
Meira, D. A.
Sartori, A.
author_role author
author2 Kaneno, Ramon [UNESP]
Soares, AMVC
Meira, D. A.
Sartori, A.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Pelizon, A. C.
Kaneno, Ramon [UNESP]
Soares, AMVC
Meira, D. A.
Sartori, A.
dc.subject.por.fl_str_mv beta-glucan
IL-12
TNF-alpha
NK activity
fungicidal activity
topic beta-glucan
IL-12
TNF-alpha
NK activity
fungicidal activity
description In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
publishDate 2005
dc.date.none.fl_str_mv 2005-01-01
2014-05-20T15:23:09Z
2014-05-20T15:23:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm
Physiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.
0862-8408
http://hdl.handle.net/11449/33989
WOS:000233101100012
8845835550637809
4977572416129527
0000-0002-4292-3298
url http://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm
http://hdl.handle.net/11449/33989
identifier_str_mv Physiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.
0862-8408
WOS:000233101100012
8845835550637809
4977572416129527
0000-0002-4292-3298
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Physiological Research
1.324
0,568
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 557-564
dc.publisher.none.fl_str_mv Acad Sciences Czech Republic, Inst Physiology
publisher.none.fl_str_mv Acad Sciences Czech Republic, Inst Physiology
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965706342629376

Registros relacionados