Avaliação ultra-sonográfica de nódulos sideróticos esplênicos em pacientes esquistossomóticos com hipertensão portal

• Autor(a) principal: Gonzalez, Thais Dias [UNIFESP]
• Data de Publicação: 2008
• Outros Autores: Santos, José Eduardo Mourão [UNIFESP], Sales, Danilo Moulin [UNIFESP], Takemoto, Kenji [UNIFESP], Capobianco, Júlia [UNIFESP], Brant, Paulo Eugênio [UNIFESP], Colleoni Neto, Ramiro [UNIFESP], Ahmed, Munneb, D'Ippolito, Giuseppe [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0100-39842008000200003; http://repositorio.unifesp.br/handle/11600/4334
• topic: Schistosomiasis mansoni; Ultrasonography; Spleen; Esquistossomose; Ultra-sonografia; Baço

OBJECTIVE: To evaluate ultrasound sensitivity and reproducibility as compared with magnetic resonance imaging as the gold standard in the detection of splenic siderotic nodules in schistosomal patients. MATERIALS AND METHODS: Initially, 21 patients with hepatosplenic schistosomiasis and diagnosed with splenic siderotic nodules by magnetic resonance imaging were ultrasonographically evaluated for determining the method sensitivity. In a second phase, the method reproducibility in the detection and quantification of siderotic nodules (A: 1-5 nodules; B: 6-20 nodules; C: > 20 nodules) was evaluated in 30 patients who were submitted to ultrasonography blindly and independently assessed by two observers. Interobserver agreement was measured by kappa statistics. RESULTS: Ultrasound sensitivity was 95.2% (95% confidence interval [77.3%; 99.2%]). Intermethod agreement in the detection of siderotic nodules was 96.7% (95% confidence interval [82.8%; 99.9%]). For classification of nodules according to their quantification, the kappa test demonstrated a statistically significant interobserver agreement (kappa = 0.67). CONCLUSION: Ultrasonography is highly sensitive and accurate in the assessment of splenic siderotic nodules in schistosomal patients.