Avaliação do efeito cicatrizante do extrato de repolho (Brassica oleracea var. capitata) em ratos Wistar

• Autor(a) principal: Sarandy, Mariáurea Matias
• Data de Publicação: 2007
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: LOCUS Repositório Institucional da UFV
• Texto Completo: http://locus.ufv.br/handle/123456789/2385
• topic: Fitoterapia; Brassica sp.; Cicatrização; Phytotherapy; Brassica spp.; Cicatrization; CNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERAL

The objective of this work was to investigate the healing effects of the extract of Brassica oleracea var. capitata to 10% in the formulations ointment and balsam, analyzing histologically the wounds induced in animal model. They were made five surgical wounds by animal, with the aid of a bistoury, in place demarcated through the opening of a test tube of 10 mm humidified in fucsina. The animals were aleatorily separate. They were appraised four treatments with six repetitions: ointment to the base of brassica sp. to 10%, balsam to the base of brassica sp. to 10%, Dersani® and saline 0,9%. Of 4 in 4 days the animals were heavy, the wounds were measured and the fragments retired for histological analysis. The data of closing of the wound were analyzed statistically by the Tukey test (p>0,05). The fragments were included in paraffin and the glass slides analyzed in polarization microscope. The results demonstrated that the balsam presented better cicatrization rate, followed for the ointment, Dersani® and saline 0,9%, and it obtained a larger amount of type I collagen fibers and better organization of those fibers.