Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/28801 https://dx.doi.org/10.1590/S0102-86502013000500003 |
Resumo: | PURPOSE: To evaluate the healing effect of carbon dioxide therapy on skin wounds induced on the back of rats. METHODS: Sixteen rats underwent excision of a round dermal-epidermal dorsal skin flap of 2.5 cm in diameter. The animals were divided into two groups, as follows: carbon dioxide group - subcutaneous injections of carbon dioxide on the day of operation and at three, six and nine days postoperatively; control group - no postoperative wound treatment. Wounds were photographed on the day of operation and at six and 14 days postoperatively for analysis of wound area and major diameter. All animals were euthanized on day 14 after surgery. The dorsal skin and the underlying muscle layer containing the wound were resected for histopathological analysis. RESULTS: There was no statistically significant difference between groups in the percentage of wound closure, in histopathological findings, or in the reduction of wound area and major diameter at 14 days postoperatively. CONCLUSION: Under the experimental conditions in which this study was conducted, carbon dioxide therapy had no effects on the healing of acute skin wounds in rats. |
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Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of ratsCuraDióxido de carbonoPeleRatosPURPOSE: To evaluate the healing effect of carbon dioxide therapy on skin wounds induced on the back of rats. METHODS: Sixteen rats underwent excision of a round dermal-epidermal dorsal skin flap of 2.5 cm in diameter. The animals were divided into two groups, as follows: carbon dioxide group - subcutaneous injections of carbon dioxide on the day of operation and at three, six and nine days postoperatively; control group - no postoperative wound treatment. Wounds were photographed on the day of operation and at six and 14 days postoperatively for analysis of wound area and major diameter. All animals were euthanized on day 14 after surgery. The dorsal skin and the underlying muscle layer containing the wound were resected for histopathological analysis. RESULTS: There was no statistically significant difference between groups in the percentage of wound closure, in histopathological findings, or in the reduction of wound area and major diameter at 14 days postoperatively. CONCLUSION: Under the experimental conditions in which this study was conducted, carbon dioxide therapy had no effects on the healing of acute skin wounds in rats.Faculdade de Medicina (FMD)Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2017-12-07T05:02:47Z2017-12-07T05:02:47Z2013-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfPENHAVEL, Maria Vitória Carmo et al. Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 5, p. 334-339, maio 2013. DOI: http://dx.doi.org/10.1590/S0102-86502013000500003. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000500003&lng=en&nrm=iso. Acesso em: 04 dez. 2020.http://repositorio.unb.br/handle/10482/28801https://dx.doi.org/10.1590/S0102-86502013000500003Acta Cirúrgica Brasileira - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License (CC BY NC 4.0). Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000500003&lng=en&tlng=en. Acesso em: 04 dez. 2020.info:eu-repo/semantics/openAccessPenhavel, Maria Vitória CarmoNascimento, Victor Henrique TavaresDurães, Eliana Ferreira RibeiroCarneiro, Fabiana PiraniSousa, João Batista deengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-25T02:15:27Zoai:repositorio.unb.br:10482/28801Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-25T02:15:27Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
title |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
spellingShingle |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats Penhavel, Maria Vitória Carmo Cura Dióxido de carbono Pele Ratos |
title_short |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
title_full |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
title_fullStr |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
title_full_unstemmed |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
title_sort |
Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats |
author |
Penhavel, Maria Vitória Carmo |
author_facet |
Penhavel, Maria Vitória Carmo Nascimento, Victor Henrique Tavares Durães, Eliana Ferreira Ribeiro Carneiro, Fabiana Pirani Sousa, João Batista de |
author_role |
author |
author2 |
Nascimento, Victor Henrique Tavares Durães, Eliana Ferreira Ribeiro Carneiro, Fabiana Pirani Sousa, João Batista de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Penhavel, Maria Vitória Carmo Nascimento, Victor Henrique Tavares Durães, Eliana Ferreira Ribeiro Carneiro, Fabiana Pirani Sousa, João Batista de |
dc.subject.por.fl_str_mv |
Cura Dióxido de carbono Pele Ratos |
topic |
Cura Dióxido de carbono Pele Ratos |
description |
PURPOSE: To evaluate the healing effect of carbon dioxide therapy on skin wounds induced on the back of rats. METHODS: Sixteen rats underwent excision of a round dermal-epidermal dorsal skin flap of 2.5 cm in diameter. The animals were divided into two groups, as follows: carbon dioxide group - subcutaneous injections of carbon dioxide on the day of operation and at three, six and nine days postoperatively; control group - no postoperative wound treatment. Wounds were photographed on the day of operation and at six and 14 days postoperatively for analysis of wound area and major diameter. All animals were euthanized on day 14 after surgery. The dorsal skin and the underlying muscle layer containing the wound were resected for histopathological analysis. RESULTS: There was no statistically significant difference between groups in the percentage of wound closure, in histopathological findings, or in the reduction of wound area and major diameter at 14 days postoperatively. CONCLUSION: Under the experimental conditions in which this study was conducted, carbon dioxide therapy had no effects on the healing of acute skin wounds in rats. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-05 2017-12-07T05:02:47Z 2017-12-07T05:02:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
PENHAVEL, Maria Vitória Carmo et al. Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 5, p. 334-339, maio 2013. DOI: http://dx.doi.org/10.1590/S0102-86502013000500003. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000500003&lng=en&nrm=iso. Acesso em: 04 dez. 2020. http://repositorio.unb.br/handle/10482/28801 https://dx.doi.org/10.1590/S0102-86502013000500003 |
identifier_str_mv |
PENHAVEL, Maria Vitória Carmo et al. Effects of carbon dioxide therapy on the healing of acute skin wounds induced on the back of rats. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 5, p. 334-339, maio 2013. DOI: http://dx.doi.org/10.1590/S0102-86502013000500003. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000500003&lng=en&nrm=iso. Acesso em: 04 dez. 2020. |
url |
http://repositorio.unb.br/handle/10482/28801 https://dx.doi.org/10.1590/S0102-86502013000500003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
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UNB |
institution |
UNB |
reponame_str |
Repositório Institucional da UnB |
collection |
Repositório Institucional da UnB |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
repositorio@unb.br |
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1814508237423116288 |