The effect of carbon dioxide therapy on composite graft survival
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/28804 https://dx.doi.org/10.1590/S0102-86502013000800006 |
Resumo: | PURPOSE: To investigate the effect of carboxytherapy in auricular composite grafts in rabbits. METHODS: An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen. RESULTS:The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively). CONCLUSIONS:Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival. |
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The effect of carbon dioxide therapy on composite graft survivalCuraDióxido de carbonoCoelhoPURPOSE: To investigate the effect of carboxytherapy in auricular composite grafts in rabbits. METHODS: An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen. RESULTS:The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively). CONCLUSIONS:Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival.Faculdade de Medicina (FMD)Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2017-12-07T05:02:47Z2017-12-07T05:02:47Z2013-08info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfDURAES, Eliana Ferreira Ribeiro et al. The effect of carbon dioxide therapy on composite graft survival. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 8, p. 589-593, ago. 2013. DOI: https://doi.org/10.1590/S0102-86502013000800006. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000800006&lng=en&nrm=iso. Acesso em: 04 dez. 2020.http://repositorio.unb.br/handle/10482/28804https://dx.doi.org/10.1590/S0102-86502013000800006Acta Cirúrgica Brasileira - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License (CC BY NC 4.0). Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000800006&lng=en&tlng=en. Acesso em: 04 dez. 2020.info:eu-repo/semantics/openAccessDurães, Eliana Ferreira RibeiroDurães, Leonardo de CastroCarneiro, Fabiana PiraniLino Júnior, Ruy de SouzaSousa, João Batista deengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-25T19:42:36Zoai:repositorio.unb.br:10482/28804Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-25T19:42:36Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
The effect of carbon dioxide therapy on composite graft survival |
title |
The effect of carbon dioxide therapy on composite graft survival |
spellingShingle |
The effect of carbon dioxide therapy on composite graft survival Durães, Eliana Ferreira Ribeiro Cura Dióxido de carbono Coelho |
title_short |
The effect of carbon dioxide therapy on composite graft survival |
title_full |
The effect of carbon dioxide therapy on composite graft survival |
title_fullStr |
The effect of carbon dioxide therapy on composite graft survival |
title_full_unstemmed |
The effect of carbon dioxide therapy on composite graft survival |
title_sort |
The effect of carbon dioxide therapy on composite graft survival |
author |
Durães, Eliana Ferreira Ribeiro |
author_facet |
Durães, Eliana Ferreira Ribeiro Durães, Leonardo de Castro Carneiro, Fabiana Pirani Lino Júnior, Ruy de Souza Sousa, João Batista de |
author_role |
author |
author2 |
Durães, Leonardo de Castro Carneiro, Fabiana Pirani Lino Júnior, Ruy de Souza Sousa, João Batista de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Durães, Eliana Ferreira Ribeiro Durães, Leonardo de Castro Carneiro, Fabiana Pirani Lino Júnior, Ruy de Souza Sousa, João Batista de |
dc.subject.por.fl_str_mv |
Cura Dióxido de carbono Coelho |
topic |
Cura Dióxido de carbono Coelho |
description |
PURPOSE: To investigate the effect of carboxytherapy in auricular composite grafts in rabbits. METHODS: An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen. RESULTS:The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively). CONCLUSIONS:Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-08 2017-12-07T05:02:47Z 2017-12-07T05:02:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
DURAES, Eliana Ferreira Ribeiro et al. The effect of carbon dioxide therapy on composite graft survival. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 8, p. 589-593, ago. 2013. DOI: https://doi.org/10.1590/S0102-86502013000800006. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000800006&lng=en&nrm=iso. Acesso em: 04 dez. 2020. http://repositorio.unb.br/handle/10482/28804 https://dx.doi.org/10.1590/S0102-86502013000800006 |
identifier_str_mv |
DURAES, Eliana Ferreira Ribeiro et al. The effect of carbon dioxide therapy on composite graft survival. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 8, p. 589-593, ago. 2013. DOI: https://doi.org/10.1590/S0102-86502013000800006. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000800006&lng=en&nrm=iso. Acesso em: 04 dez. 2020. |
url |
http://repositorio.unb.br/handle/10482/28804 https://dx.doi.org/10.1590/S0102-86502013000800006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
instacron_str |
UNB |
institution |
UNB |
reponame_str |
Repositório Institucional da UnB |
collection |
Repositório Institucional da UnB |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
repositorio@unb.br |
_version_ |
1810580714282811392 |