Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss

• Autor(a) principal: Moreira de Andrade, Sâmia
• Data de Publicação: 2023
• Outros Autores: Macedo de Andrade, Maria Victória, Almeida de Faria, Pedro Henrique, Vieira Rosa, Luís Marcelo, Cavalcante Costa, Plínio Robson, Freitas Pires, Luiz Gustavo
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Diversitas Journal
• Texto Completo: https://diversitasjournal.com.br/diversitas_journal/article/view/2720
• topic: Diabetes; Obesidade; Emagrecimento; Uso racional de medicamentos; Diabetes; Obesity; Slimming; Antidiabetic drugs; Rational use of drugs

The present study aimed to carry out a bibliographical survey of antidiabetic drugs used for weight loss and their consequences for human health. The drugs most commonly reported in the literature were Metformin, Liraglutide and Semaglutide. The three drugs proved to be effective in weight loss, with Liraglutide having the most pronounced effect, including in clinical studies. Metformin and Semaglutide have been shown to reduce weight, especially when associated with the practice of physical exercise and a change in eating style. However, these drugs have not yet been approved for the purpose of weight loss, and a series of side effects have been reported, mainly associated with the gastrointestinal system, such as nausea, vomiting and diarrhea. Based on the evaluated data, the best way to reduce body weight remains the practice of physical activity and lifestyle changes, and since such practices are not enough, one can opt for the use of anorectics with the proper prescription. and guidance from a health professional. We also highlight the greatest need for the pharmacist, who is responsible for the interface between the drug and the patient, in the education process to avoid the irrational use of antidiabetic drugs in order to lose weight.