Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Diversitas Journal |
Texto Completo: | https://diversitasjournal.com.br/diversitas_journal/article/view/2720 |
Resumo: | The present study aimed to carry out a bibliographical survey of antidiabetic drugs used for weight loss and their consequences for human health. The drugs most commonly reported in the literature were Metformin, Liraglutide and Semaglutide. The three drugs proved to be effective in weight loss, with Liraglutide having the most pronounced effect, including in clinical studies. Metformin and Semaglutide have been shown to reduce weight, especially when associated with the practice of physical exercise and a change in eating style. However, these drugs have not yet been approved for the purpose of weight loss, and a series of side effects have been reported, mainly associated with the gastrointestinal system, such as nausea, vomiting and diarrhea. Based on the evaluated data, the best way to reduce body weight remains the practice of physical activity and lifestyle changes, and since such practices are not enough, one can opt for the use of anorectics with the proper prescription. and guidance from a health professional. We also highlight the greatest need for the pharmacist, who is responsible for the interface between the drug and the patient, in the education process to avoid the irrational use of antidiabetic drugs in order to lose weight. |
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Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight lossMetformina, Liraglutida e Semaglutida: Medicamentos antidiabéticos utilizados com a finalidade de perda de pesoDiabetesObesidadeEmagrecimentoUso racional de medicamentosDiabetesObesitySlimmingAntidiabetic drugsRational use of drugsThe present study aimed to carry out a bibliographical survey of antidiabetic drugs used for weight loss and their consequences for human health. The drugs most commonly reported in the literature were Metformin, Liraglutide and Semaglutide. The three drugs proved to be effective in weight loss, with Liraglutide having the most pronounced effect, including in clinical studies. Metformin and Semaglutide have been shown to reduce weight, especially when associated with the practice of physical exercise and a change in eating style. However, these drugs have not yet been approved for the purpose of weight loss, and a series of side effects have been reported, mainly associated with the gastrointestinal system, such as nausea, vomiting and diarrhea. Based on the evaluated data, the best way to reduce body weight remains the practice of physical activity and lifestyle changes, and since such practices are not enough, one can opt for the use of anorectics with the proper prescription. and guidance from a health professional. We also highlight the greatest need for the pharmacist, who is responsible for the interface between the drug and the patient, in the education process to avoid the irrational use of antidiabetic drugs in order to lose weight.O presente estudo objetivou realizar um levantamento bibliográfico de medicamentos antidiabéticos utilizados para emagrecimento e suas consequências para a saúde humana. Os medicamentos mais comumente relatados na literatura foram Metformina, Liraglutida e Semaglutida. Os três medicamentos demonstraram ser efetivos no emagrecimento, tendo a Liraglutida efeito mais pronunciado, inclusive em estudos clínicos. Metformina e Semaglutida demonstraram reduzir peso principalmente quando associados à prática de exercício físico e mudança de hábito alimentar. Entretanto, esses medicamentos ainda não foram aprovados com a finalidade de emagrecimento, e uma série de efeitos colaterais foram relatados, principalmente associados ao sistema gastrointestinal como náusea, vômito e diarréia. Com base nos dados avaliados, a melhor forma de reduzir o peso corporal continua sendo a prática de atividade física e mudança do estilo de vida, e uma vez que tais práticas não são suficientes pode-se optar pelo uso de anorexígeno com a devida prescrição e orientação de um profissional de saúde. Destacamos ainda a maior necessidade do farmacêutico, responsável pela interface entre o medicamento e o paciente, no processo de educação para evitar o uso irracional de medicamentos antidiabéticos no intuito de emagrecer.Universidade Estadual de Alagoas - Eduneal2023-11-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://diversitasjournal.com.br/diversitas_journal/article/view/272010.48017/dj.v8i4.2720Diversitas Journal; Vol. 8 No. 4 (2023): Science, innovation and the role of the university in the production of knowledge; 2723-2731Diversitas Journal; Vol. 8 Núm. 4 (2023): Ciencia, innovación y el papel de la universidad en la producción de conocimiento; 2723-2731Diversitas Journal; v. 8 n. 4 (2023): Ciência, inovação e o papel da universidade na produção de conhecimento; 2723-27312525-521510.48017/dj.v8i4reponame:Diversitas Journalinstname:Universidade Estadual de Alagoas (UNEAL)instacron:UNEALporenghttps://diversitasjournal.com.br/diversitas_journal/article/view/2720/2288https://diversitasjournal.com.br/diversitas_journal/article/view/2720/2289Copyright (c) 2023 Sâmia Moreira de Andrade, Maria Victória Macedo de Andrade, Pedro Henrique Almeida de Faria, Luís Marcelo Vieira Rosa, Plínio Robson Cavalcante Costa, Luiz Gustavo Freitas Pireshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMoreira de Andrade, SâmiaMacedo de Andrade, Maria VictóriaAlmeida de Faria, Pedro HenriqueVieira Rosa, Luís MarceloCavalcante Costa, Plínio RobsonFreitas Pires, Luiz Gustavo2023-12-29T21:54:59Zoai:ojs.diversitasjournal.com.br:article/2720Revistahttps://diversitasjournal.com.br/diversitas_journal/indexPUBhttps://www.e-publicacoes.uerj.br/index.php/muralinternacional/oairevistadiversitasjournal@gmail.com2525-52152525-5215opendoar:2023-12-29T21:54:59Diversitas Journal - Universidade Estadual de Alagoas (UNEAL)false |
dc.title.none.fl_str_mv |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss Metformina, Liraglutida e Semaglutida: Medicamentos antidiabéticos utilizados com a finalidade de perda de peso |
title |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss |
spellingShingle |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss Moreira de Andrade, Sâmia Diabetes Obesidade Emagrecimento Uso racional de medicamentos Diabetes Obesity Slimming Antidiabetic drugs Rational use of drugs |
title_short |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss |
title_full |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss |
title_fullStr |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss |
title_full_unstemmed |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss |
title_sort |
Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss |
author |
Moreira de Andrade, Sâmia |
author_facet |
Moreira de Andrade, Sâmia Macedo de Andrade, Maria Victória Almeida de Faria, Pedro Henrique Vieira Rosa, Luís Marcelo Cavalcante Costa, Plínio Robson Freitas Pires, Luiz Gustavo |
author_role |
author |
author2 |
Macedo de Andrade, Maria Victória Almeida de Faria, Pedro Henrique Vieira Rosa, Luís Marcelo Cavalcante Costa, Plínio Robson Freitas Pires, Luiz Gustavo |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Moreira de Andrade, Sâmia Macedo de Andrade, Maria Victória Almeida de Faria, Pedro Henrique Vieira Rosa, Luís Marcelo Cavalcante Costa, Plínio Robson Freitas Pires, Luiz Gustavo |
dc.subject.por.fl_str_mv |
Diabetes Obesidade Emagrecimento Uso racional de medicamentos Diabetes Obesity Slimming Antidiabetic drugs Rational use of drugs |
topic |
Diabetes Obesidade Emagrecimento Uso racional de medicamentos Diabetes Obesity Slimming Antidiabetic drugs Rational use of drugs |
description |
The present study aimed to carry out a bibliographical survey of antidiabetic drugs used for weight loss and their consequences for human health. The drugs most commonly reported in the literature were Metformin, Liraglutide and Semaglutide. The three drugs proved to be effective in weight loss, with Liraglutide having the most pronounced effect, including in clinical studies. Metformin and Semaglutide have been shown to reduce weight, especially when associated with the practice of physical exercise and a change in eating style. However, these drugs have not yet been approved for the purpose of weight loss, and a series of side effects have been reported, mainly associated with the gastrointestinal system, such as nausea, vomiting and diarrhea. Based on the evaluated data, the best way to reduce body weight remains the practice of physical activity and lifestyle changes, and since such practices are not enough, one can opt for the use of anorectics with the proper prescription. and guidance from a health professional. We also highlight the greatest need for the pharmacist, who is responsible for the interface between the drug and the patient, in the education process to avoid the irrational use of antidiabetic drugs in order to lose weight. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-11-02 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://diversitasjournal.com.br/diversitas_journal/article/view/2720 10.48017/dj.v8i4.2720 |
url |
https://diversitasjournal.com.br/diversitas_journal/article/view/2720 |
identifier_str_mv |
10.48017/dj.v8i4.2720 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://diversitasjournal.com.br/diversitas_journal/article/view/2720/2288 https://diversitasjournal.com.br/diversitas_journal/article/view/2720/2289 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Alagoas - Eduneal |
publisher.none.fl_str_mv |
Universidade Estadual de Alagoas - Eduneal |
dc.source.none.fl_str_mv |
Diversitas Journal; Vol. 8 No. 4 (2023): Science, innovation and the role of the university in the production of knowledge; 2723-2731 Diversitas Journal; Vol. 8 Núm. 4 (2023): Ciencia, innovación y el papel de la universidad en la producción de conocimiento; 2723-2731 Diversitas Journal; v. 8 n. 4 (2023): Ciência, inovação e o papel da universidade na produção de conhecimento; 2723-2731 2525-5215 10.48017/dj.v8i4 reponame:Diversitas Journal instname:Universidade Estadual de Alagoas (UNEAL) instacron:UNEAL |
instname_str |
Universidade Estadual de Alagoas (UNEAL) |
instacron_str |
UNEAL |
institution |
UNEAL |
reponame_str |
Diversitas Journal |
collection |
Diversitas Journal |
repository.name.fl_str_mv |
Diversitas Journal - Universidade Estadual de Alagoas (UNEAL) |
repository.mail.fl_str_mv |
revistadiversitasjournal@gmail.com |
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1797051273997975552 |