Cariogenic and erosive potential of pediatric medicines and vitamin supplements
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Odontologia da UNESP |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772022000100404 |
Resumo: | Abstract Introduction Pharmaceutical pediatric formulations with low in pH and high in total titratable acidicity used frequently and over long periods of time, have the potential to produce erosive lesions in teeth. On the other hand, high concentration of sucrose, the nocturnal use and the lack of hygiene after its administration, are some factors that can contribute to the cariogenic potential of these formulations. Objective To evaluate in vitro the cariogenic and erosive potential of medicines and liquid vitamins and mineral supplements for pediatric use. Material and method Medicines (n=41) and liquid vitamins and mineral supplements (n=12) childish were selected and analyzed for their physicochemical properties, pH, total titratable acidity (TTA) and total soluble solids concentration (TSS/°Brix). The package inserts and labels were analyzed to identify the composition regarding the content of sugars and acidulants, in addition to the side effects related to salivary flow. Result The pH analysis indicated that there was greater variation in the observed averages in the medication group. As for the TTA at pH 5.5, supplements and medicines groups showed significant variation between the means found (p<0.05). The TTA results at pH 7.0 showed that the highest mean found was in the class of antihistamines and the lowest in the class of drugs that contain the association of antitussives and antihistamines. The analyses TSS demonstrated that across all drug classes and supplements the amount of TSS varied significantly (p<0.05) in all classes of medicines and supplements. Conclusion Most medicines and pediatric liquid vitamin and mineral supplements demonstrated significantly different behaviors within the group itself regarding the variables analyzed that constitute risk factors for the development of dental caries and erosion. |
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Cariogenic and erosive potential of pediatric medicines and vitamin supplementsDental cariestooth erosionpharmaceutical preparationsAbstract Introduction Pharmaceutical pediatric formulations with low in pH and high in total titratable acidicity used frequently and over long periods of time, have the potential to produce erosive lesions in teeth. On the other hand, high concentration of sucrose, the nocturnal use and the lack of hygiene after its administration, are some factors that can contribute to the cariogenic potential of these formulations. Objective To evaluate in vitro the cariogenic and erosive potential of medicines and liquid vitamins and mineral supplements for pediatric use. Material and method Medicines (n=41) and liquid vitamins and mineral supplements (n=12) childish were selected and analyzed for their physicochemical properties, pH, total titratable acidity (TTA) and total soluble solids concentration (TSS/°Brix). The package inserts and labels were analyzed to identify the composition regarding the content of sugars and acidulants, in addition to the side effects related to salivary flow. Result The pH analysis indicated that there was greater variation in the observed averages in the medication group. As for the TTA at pH 5.5, supplements and medicines groups showed significant variation between the means found (p<0.05). The TTA results at pH 7.0 showed that the highest mean found was in the class of antihistamines and the lowest in the class of drugs that contain the association of antitussives and antihistamines. The analyses TSS demonstrated that across all drug classes and supplements the amount of TSS varied significantly (p<0.05) in all classes of medicines and supplements. Conclusion Most medicines and pediatric liquid vitamin and mineral supplements demonstrated significantly different behaviors within the group itself regarding the variables analyzed that constitute risk factors for the development of dental caries and erosion.Universidade Estadual Paulista Júlio de Mesquita Filho2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772022000100404Revista de Odontologia da UNESP v.51 2022reponame:Revista de Odontologia da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/1807-2577.00622info:eu-repo/semantics/openAccessCOUTINHO,Luciene SouzaSANDE,Ana Caroline Magalhães NeriNUNES,Natália Novais VasconcelosOLIVEIRA,Rafaela SilvaCAMPOS,Elisângela de Jesuseng2022-05-12T00:00:00Zoai:scielo:S1807-25772022000100404Revistahttps://www.revodontolunesp.com.br/PUBhttps://old.scielo.br/oai/scielo-oai.php||adriana@foar.unesp.br1807-25770101-1774opendoar:2022-05-12T00:00Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
title |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
spellingShingle |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements COUTINHO,Luciene Souza Dental caries tooth erosion pharmaceutical preparations |
title_short |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
title_full |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
title_fullStr |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
title_full_unstemmed |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
title_sort |
Cariogenic and erosive potential of pediatric medicines and vitamin supplements |
author |
COUTINHO,Luciene Souza |
author_facet |
COUTINHO,Luciene Souza SANDE,Ana Caroline Magalhães Neri NUNES,Natália Novais Vasconcelos OLIVEIRA,Rafaela Silva CAMPOS,Elisângela de Jesus |
author_role |
author |
author2 |
SANDE,Ana Caroline Magalhães Neri NUNES,Natália Novais Vasconcelos OLIVEIRA,Rafaela Silva CAMPOS,Elisângela de Jesus |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
COUTINHO,Luciene Souza SANDE,Ana Caroline Magalhães Neri NUNES,Natália Novais Vasconcelos OLIVEIRA,Rafaela Silva CAMPOS,Elisângela de Jesus |
dc.subject.por.fl_str_mv |
Dental caries tooth erosion pharmaceutical preparations |
topic |
Dental caries tooth erosion pharmaceutical preparations |
description |
Abstract Introduction Pharmaceutical pediatric formulations with low in pH and high in total titratable acidicity used frequently and over long periods of time, have the potential to produce erosive lesions in teeth. On the other hand, high concentration of sucrose, the nocturnal use and the lack of hygiene after its administration, are some factors that can contribute to the cariogenic potential of these formulations. Objective To evaluate in vitro the cariogenic and erosive potential of medicines and liquid vitamins and mineral supplements for pediatric use. Material and method Medicines (n=41) and liquid vitamins and mineral supplements (n=12) childish were selected and analyzed for their physicochemical properties, pH, total titratable acidity (TTA) and total soluble solids concentration (TSS/°Brix). The package inserts and labels were analyzed to identify the composition regarding the content of sugars and acidulants, in addition to the side effects related to salivary flow. Result The pH analysis indicated that there was greater variation in the observed averages in the medication group. As for the TTA at pH 5.5, supplements and medicines groups showed significant variation between the means found (p<0.05). The TTA results at pH 7.0 showed that the highest mean found was in the class of antihistamines and the lowest in the class of drugs that contain the association of antitussives and antihistamines. The analyses TSS demonstrated that across all drug classes and supplements the amount of TSS varied significantly (p<0.05) in all classes of medicines and supplements. Conclusion Most medicines and pediatric liquid vitamin and mineral supplements demonstrated significantly different behaviors within the group itself regarding the variables analyzed that constitute risk factors for the development of dental caries and erosion. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772022000100404 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772022000100404 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1807-2577.00622 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista Júlio de Mesquita Filho |
publisher.none.fl_str_mv |
Universidade Estadual Paulista Júlio de Mesquita Filho |
dc.source.none.fl_str_mv |
Revista de Odontologia da UNESP v.51 2022 reponame:Revista de Odontologia da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Revista de Odontologia da UNESP |
collection |
Revista de Odontologia da UNESP |
repository.name.fl_str_mv |
Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
||adriana@foar.unesp.br |
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1748958561261584384 |