Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Odontologia da UNESP |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299 |
Resumo: | AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy. |
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Aloe vera as vehicle to mineral trioxide aggregate: study in bone repairBone regenerationphytotherapeutic drugsinflammationhistologyendodonticsAIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy.Universidade Estadual Paulista Júlio de Mesquita Filho2014-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299Revista de Odontologia da UNESP v.43 n.5 2014reponame:Revista de Odontologia da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/rou.2014.048info:eu-repo/semantics/openAccessFÉ,Jessyca Leal MouraCOELHO,Caroline de AraújoDAMASCENA,Germana MirandaSOARES,Isadora Mello VilarinhoALVES,Flávio RibeiroSANTOS,Ísidra Manuela Sousa PortelaCARVALHO,Carmen Milena Rodrigues Siqueiraeng2015-09-24T00:00:00Zoai:scielo:S1807-25772014000500299Revistahttps://www.revodontolunesp.com.br/PUBhttps://old.scielo.br/oai/scielo-oai.php||adriana@foar.unesp.br1807-25770101-1774opendoar:2015-09-24T00:00Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
spellingShingle |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair FÉ,Jessyca Leal Moura Bone regeneration phytotherapeutic drugs inflammation histology endodontics |
title_short |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_full |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_fullStr |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_full_unstemmed |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_sort |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
author |
FÉ,Jessyca Leal Moura |
author_facet |
FÉ,Jessyca Leal Moura COELHO,Caroline de Araújo DAMASCENA,Germana Miranda SOARES,Isadora Mello Vilarinho ALVES,Flávio Ribeiro SANTOS,Ísidra Manuela Sousa Portela CARVALHO,Carmen Milena Rodrigues Siqueira |
author_role |
author |
author2 |
COELHO,Caroline de Araújo DAMASCENA,Germana Miranda SOARES,Isadora Mello Vilarinho ALVES,Flávio Ribeiro SANTOS,Ísidra Manuela Sousa Portela CARVALHO,Carmen Milena Rodrigues Siqueira |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
FÉ,Jessyca Leal Moura COELHO,Caroline de Araújo DAMASCENA,Germana Miranda SOARES,Isadora Mello Vilarinho ALVES,Flávio Ribeiro SANTOS,Ísidra Manuela Sousa Portela CARVALHO,Carmen Milena Rodrigues Siqueira |
dc.subject.por.fl_str_mv |
Bone regeneration phytotherapeutic drugs inflammation histology endodontics |
topic |
Bone regeneration phytotherapeutic drugs inflammation histology endodontics |
description |
AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/rou.2014.048 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista Júlio de Mesquita Filho |
publisher.none.fl_str_mv |
Universidade Estadual Paulista Júlio de Mesquita Filho |
dc.source.none.fl_str_mv |
Revista de Odontologia da UNESP v.43 n.5 2014 reponame:Revista de Odontologia da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Revista de Odontologia da UNESP |
collection |
Revista de Odontologia da UNESP |
repository.name.fl_str_mv |
Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
||adriana@foar.unesp.br |
_version_ |
1748958558891802624 |