Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair

Detalhes bibliográficos
Autor(a) principal: FÉ,Jessyca Leal Moura
Data de Publicação: 2014
Outros Autores: COELHO,Caroline de Araújo, DAMASCENA,Germana Miranda, SOARES,Isadora Mello Vilarinho, ALVES,Flávio Ribeiro, SANTOS,Ísidra Manuela Sousa Portela, CARVALHO,Carmen Milena Rodrigues Siqueira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Odontologia da UNESP
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299
Resumo: AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy.
id UNESP-16_da76b50f82e2445d26156f007e9be52c
oai_identifier_str oai:scielo:S1807-25772014000500299
network_acronym_str UNESP-16
network_name_str Revista de Odontologia da UNESP
repository_id_str
spelling Aloe vera as vehicle to mineral trioxide aggregate: study in bone repairBone regenerationphytotherapeutic drugsinflammationhistologyendodonticsAIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy.Universidade Estadual Paulista Júlio de Mesquita Filho2014-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299Revista de Odontologia da UNESP v.43 n.5 2014reponame:Revista de Odontologia da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/rou.2014.048info:eu-repo/semantics/openAccessFÉ,Jessyca Leal MouraCOELHO,Caroline de AraújoDAMASCENA,Germana MirandaSOARES,Isadora Mello VilarinhoALVES,Flávio RibeiroSANTOS,Ísidra Manuela Sousa PortelaCARVALHO,Carmen Milena Rodrigues Siqueiraeng2015-09-24T00:00:00Zoai:scielo:S1807-25772014000500299Revistahttps://www.revodontolunesp.com.br/PUBhttps://old.scielo.br/oai/scielo-oai.php||adriana@foar.unesp.br1807-25770101-1774opendoar:2015-09-24T00:00Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
title Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
spellingShingle Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
FÉ,Jessyca Leal Moura
Bone regeneration
phytotherapeutic drugs
inflammation
histology
endodontics
title_short Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
title_full Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
title_fullStr Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
title_full_unstemmed Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
title_sort Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
author FÉ,Jessyca Leal Moura
author_facet FÉ,Jessyca Leal Moura
COELHO,Caroline de Araújo
DAMASCENA,Germana Miranda
SOARES,Isadora Mello Vilarinho
ALVES,Flávio Ribeiro
SANTOS,Ísidra Manuela Sousa Portela
CARVALHO,Carmen Milena Rodrigues Siqueira
author_role author
author2 COELHO,Caroline de Araújo
DAMASCENA,Germana Miranda
SOARES,Isadora Mello Vilarinho
ALVES,Flávio Ribeiro
SANTOS,Ísidra Manuela Sousa Portela
CARVALHO,Carmen Milena Rodrigues Siqueira
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv FÉ,Jessyca Leal Moura
COELHO,Caroline de Araújo
DAMASCENA,Germana Miranda
SOARES,Isadora Mello Vilarinho
ALVES,Flávio Ribeiro
SANTOS,Ísidra Manuela Sousa Portela
CARVALHO,Carmen Milena Rodrigues Siqueira
dc.subject.por.fl_str_mv Bone regeneration
phytotherapeutic drugs
inflammation
histology
endodontics
topic Bone regeneration
phytotherapeutic drugs
inflammation
histology
endodontics
description AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy.
publishDate 2014
dc.date.none.fl_str_mv 2014-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/rou.2014.048
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Estadual Paulista Júlio de Mesquita Filho
publisher.none.fl_str_mv Universidade Estadual Paulista Júlio de Mesquita Filho
dc.source.none.fl_str_mv Revista de Odontologia da UNESP v.43 n.5 2014
reponame:Revista de Odontologia da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Revista de Odontologia da UNESP
collection Revista de Odontologia da UNESP
repository.name.fl_str_mv Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv ||adriana@foar.unesp.br
_version_ 1748958558891802624