Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian journal of oral sciences (Online) |
Texto Completo: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641885 |
Resumo: | Aim: To compare the efficacy of platelet rich plasma (PRP) associated with bioactive glass (BG) and BG alone in the treatment of periodontal intrabony defects. Methods: Ten patients participated of the study. Using a split-mouth design, interproximal bony defects were surgically treated with either PRP/BG or BG alone. The clinical parameters plaque index, gingival index, gingival bleeding index, pocket probing depth (PPD), clinical attachment level (CAL) and gingival recession were recorded, and the defect fill was evaluated radiographically at baseline and 3 and 6 months after surgery. Results: At 6 months after therapy, the PRP/BG group showed mean PPD reduction of 3.4±1.4 mm, CAL mean gain of 4.3±1.3 mm, and defect fill of 3.5±1.0 mm. The BG group showed mean PPD reduction of 2.6±1.1 mm, mean CAL gain of 3.3±1.3 mm, and defect fill of 3.1±1.2mm. There was statistically significant greater PPD reduction at 3 months and CAL gain at 6 months for PRP/BG compared to BG alone, but no significant difference was observed in defect fill. Conclusions: Both therapies resulted in significant PPD reduction, CAL gain and defect fill. The association of PRP with a BG graft material seemed to add some benefits to the improvement of the clinical parameters in the treatment of intrabony defects. |
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UNICAMP-8 |
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Brazilian journal of oral sciences (Online) |
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Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humansIntra-bony defectPeriodontal regenerationPlatelet-rich plasmaBioactive glassOdontologyAim: To compare the efficacy of platelet rich plasma (PRP) associated with bioactive glass (BG) and BG alone in the treatment of periodontal intrabony defects. Methods: Ten patients participated of the study. Using a split-mouth design, interproximal bony defects were surgically treated with either PRP/BG or BG alone. The clinical parameters plaque index, gingival index, gingival bleeding index, pocket probing depth (PPD), clinical attachment level (CAL) and gingival recession were recorded, and the defect fill was evaluated radiographically at baseline and 3 and 6 months after surgery. Results: At 6 months after therapy, the PRP/BG group showed mean PPD reduction of 3.4±1.4 mm, CAL mean gain of 4.3±1.3 mm, and defect fill of 3.5±1.0 mm. The BG group showed mean PPD reduction of 2.6±1.1 mm, mean CAL gain of 3.3±1.3 mm, and defect fill of 3.1±1.2mm. There was statistically significant greater PPD reduction at 3 months and CAL gain at 6 months for PRP/BG compared to BG alone, but no significant difference was observed in defect fill. Conclusions: Both therapies resulted in significant PPD reduction, CAL gain and defect fill. The association of PRP with a BG graft material seemed to add some benefits to the improvement of the clinical parameters in the treatment of intrabony defects.Universidade Estadual de Campinas2015-11-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/864188510.20396/bjos.v9i2.8641885Brazilian Journal of Oral Sciences; v. 9 n. 2 (2010): Apr./Jun.; 106-114Brazilian Journal of Oral Sciences; Vol. 9 No. 2 (2010): Apr./Jun.; 106-1141677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641885/9385Kaur, ManmeetRamakrishnan, T.Amblavanan, N.Emmadi, Pamelainfo:eu-repo/semantics/openAccess2015-11-25T08:43:20Zoai:ojs.periodicos.sbu.unicamp.br:article/8641885Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2015-11-25T08:43:20Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false |
dc.title.none.fl_str_mv |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
title |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
spellingShingle |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans Kaur, Manmeet Intra-bony defect Periodontal regeneration Platelet-rich plasma Bioactive glass Odontology |
title_short |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
title_full |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
title_fullStr |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
title_full_unstemmed |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
title_sort |
Effect of platelet-rich plasma and bioactive glass in the treatment of intrabony defects - a split-mouth study in humans |
author |
Kaur, Manmeet |
author_facet |
Kaur, Manmeet Ramakrishnan, T. Amblavanan, N. Emmadi, Pamela |
author_role |
author |
author2 |
Ramakrishnan, T. Amblavanan, N. Emmadi, Pamela |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Kaur, Manmeet Ramakrishnan, T. Amblavanan, N. Emmadi, Pamela |
dc.subject.por.fl_str_mv |
Intra-bony defect Periodontal regeneration Platelet-rich plasma Bioactive glass Odontology |
topic |
Intra-bony defect Periodontal regeneration Platelet-rich plasma Bioactive glass Odontology |
description |
Aim: To compare the efficacy of platelet rich plasma (PRP) associated with bioactive glass (BG) and BG alone in the treatment of periodontal intrabony defects. Methods: Ten patients participated of the study. Using a split-mouth design, interproximal bony defects were surgically treated with either PRP/BG or BG alone. The clinical parameters plaque index, gingival index, gingival bleeding index, pocket probing depth (PPD), clinical attachment level (CAL) and gingival recession were recorded, and the defect fill was evaluated radiographically at baseline and 3 and 6 months after surgery. Results: At 6 months after therapy, the PRP/BG group showed mean PPD reduction of 3.4±1.4 mm, CAL mean gain of 4.3±1.3 mm, and defect fill of 3.5±1.0 mm. The BG group showed mean PPD reduction of 2.6±1.1 mm, mean CAL gain of 3.3±1.3 mm, and defect fill of 3.1±1.2mm. There was statistically significant greater PPD reduction at 3 months and CAL gain at 6 months for PRP/BG compared to BG alone, but no significant difference was observed in defect fill. Conclusions: Both therapies resulted in significant PPD reduction, CAL gain and defect fill. The association of PRP with a BG graft material seemed to add some benefits to the improvement of the clinical parameters in the treatment of intrabony defects. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641885 10.20396/bjos.v9i2.8641885 |
url |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641885 |
identifier_str_mv |
10.20396/bjos.v9i2.8641885 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641885/9385 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
dc.source.none.fl_str_mv |
Brazilian Journal of Oral Sciences; v. 9 n. 2 (2010): Apr./Jun.; 106-114 Brazilian Journal of Oral Sciences; Vol. 9 No. 2 (2010): Apr./Jun.; 106-114 1677-3225 reponame:Brazilian journal of oral sciences (Online) instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
instname_str |
Universidade Estadual de Campinas (UNICAMP) |
instacron_str |
UNICAMP |
institution |
UNICAMP |
reponame_str |
Brazilian journal of oral sciences (Online) |
collection |
Brazilian journal of oral sciences (Online) |
repository.name.fl_str_mv |
Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP) |
repository.mail.fl_str_mv |
brjorals@fop.unicamp.br||brjorals@fop.unicamp.br |
_version_ |
1800216400564846592 |