Use of L-PRF in the treatment of osteoradionecrosis

Detalhes bibliográficos
Autor(a) principal: Carvalho, Romayla de Andrade
Data de Publicação: 2022
Outros Autores: Gomes, Ana Viviam Souza Ferro, Ferraz, Rodolfo Adriano Rocha, Castro, Francisca Ângela Sousa, Pereira, Estefany Monteiro Lopes, Ferreira , Gerson Luís Castro, Fortaleza, Vitória Gindri, Fontenele, Maria Éryka Giovanna de Brito
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/28140
Resumo: Osteonecrosis is a pathology caused by necrosis of the gnathic bones of the maxilla and mandible. Either through antiresorptive drugs or radiotherapy. L-PRF is a platelet concentrate composed of leukocytes and growth factors capable of restoring vascularization and healing of soft and hard tissues. In addition to being the newest alternative treatment for osteonecrosis. In view of this, the work aims to evaluate the effectiveness of L-PRF in the prevention and treatment of osteonecrosis, and to clarify the mechanisms of this platelet concentrate in maxillary and mandibular osteonecrosis, in addition to other therapeutic approaches combined with L-PRF. Regarding the methodology, it is based on a literature review with a qualitative approach, which used the PUBMED, Google Scholar, Medline and IBECS databases. In the initial research, it resulted in 377 articles, after applying the filters that refer to articles published between 2017 and 2022, it generated a total of 21 articles chosen. According to the literature, L-PRF is effective in osteonecrosis, however, there are differences in the literature, as well as the fact that there is still no gold standard treatment. Therefore, L-PRF is effective, but it is not yet standardized, while each case of osteonecrosis has its peculiarity. However, when combined with other forms of treatments such as human bone morphogenetic protein (PMBs), the synergistic effect of these therapeutics accelerates the patient's healing process.
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spelling Use of L-PRF in the treatment of osteoradionecrosisUso de L-PRF en el tratamiento de la osteorradionecrosisUso do L-PRF no tratamento de osteorradionecrose L-PRFNecrosis óseaBifosfonato.L-PRFBone necrosisBisphosphonate.L-PRFNecrose ósseaBifosfonato.Osteonecrosis is a pathology caused by necrosis of the gnathic bones of the maxilla and mandible. Either through antiresorptive drugs or radiotherapy. L-PRF is a platelet concentrate composed of leukocytes and growth factors capable of restoring vascularization and healing of soft and hard tissues. In addition to being the newest alternative treatment for osteonecrosis. In view of this, the work aims to evaluate the effectiveness of L-PRF in the prevention and treatment of osteonecrosis, and to clarify the mechanisms of this platelet concentrate in maxillary and mandibular osteonecrosis, in addition to other therapeutic approaches combined with L-PRF. Regarding the methodology, it is based on a literature review with a qualitative approach, which used the PUBMED, Google Scholar, Medline and IBECS databases. In the initial research, it resulted in 377 articles, after applying the filters that refer to articles published between 2017 and 2022, it generated a total of 21 articles chosen. According to the literature, L-PRF is effective in osteonecrosis, however, there are differences in the literature, as well as the fact that there is still no gold standard treatment. Therefore, L-PRF is effective, but it is not yet standardized, while each case of osteonecrosis has its peculiarity. However, when combined with other forms of treatments such as human bone morphogenetic protein (PMBs), the synergistic effect of these therapeutics accelerates the patient's healing process.La osteonecrosis es una patología causada por la necrosis de los huesos gnáticos del maxilar y la mandíbula. Ya sea a través de fármacos antirresortivos o radioterapia. L-PRF es un concentrado de plaquetas compuesto por leucocitos y factores de crecimiento capaz de restaurar la vascularización y cicatrización de tejidos blandos y duros. Además de ser la alternativa de tratamiento más novedosa para la osteonecrosis. Ante ello, el trabajo pretende evaluar la eficacia de la L-PRF en la prevención y tratamiento de la osteonecrosis, y esclarecer los mecanismos de este concentrado plaquetario en la osteonecrosis maxilar y mandibular, además de otros abordajes terapéuticos combinados con la L-PRF . En cuanto a la metodología, se basa en una revisión de literatura con enfoque cualitativo, que utilizó las bases de datos PUBMED, Google Scholar, Medline e IBECS. En la investigación inicial dio como resultado 377 artículos, luego de aplicar los filtros que hacen referencia a artículos publicados entre 2017 y 2022, generó un total de 21 artículos escogidos. Según la literatura, la L-PRF es eficaz en la osteonecrosis, sin embargo, existen diferencias en la literatura, así como que aún no existe un tratamiento estándar de oro. Por lo tanto, L-PRF es efectivo, pero aún no está estandarizado, mientras que cada caso de osteonecrosis tiene su particularidad. Sin embargo, cuando se combina con otras formas de tratamientos, como la proteína morfogenética ósea humana (PMB), el efecto sinérgico de estas terapias acelera el proceso de curación del paciente.A osteonecrose é uma patologia ocasionada pela necrose dos ossos gnáticos da maxila e mandíbula. Seja por meio de medicamentos antirreabsortivos, seja pela radioterapia. O L-PRF é um concentrado plaquetário composto por leucócitos e fatores de crescimento capazes de restaurar a vascularização e cicatrização de tecidos moles e duros. Além de ser o mais novo tratamento alternativo da osteonecrose. Visto isso, o trabalho objetifica-se em avaliar a eficácia do L-PRF na prevenção e tratamento da osteonecrose,e esclarecer os mecanismos desse concentrado plaquetário na osteonecrose de maxila e mandíbula, além de outras abordagens terapêuticas combinada com o L-PRF. Em relação a metodologia, é baseada em uma revisão de literatura com abordagem qualitativa, a qual usou as bases de dados PUBMED, Google Acadêmico, Medline e IBECS. Na pesquisa inicial, resultou em 377 artigos, após a aplicação dos filtros que se remetem a artigos publicados entre 2017 e 2022, gerou um total de 21 artigos escolhidos. Conforme na literatura, o L-PRF tem eficácia na osteonecrose, no entanto, apresenta divergências na literatura, como também pelo fato de não existir ainda um tratamento padrão-ouro. Portanto, o L-PRF é eficaz, mas não é padronizado ainda, ao passo que cada caso de osteonecrose tem sua peculiaridade. No entanto, quando combinado com outras formas de tratamentos, como a proteína morfogenética humana óssea (PMBs), o efeito sinérgico desses terapêuticos acelera o processo de cura do paciente.Research, Society and Development2022-04-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2814010.33448/rsd-v11i5.28140Research, Society and Development; Vol. 11 No. 5; e22111528140Research, Society and Development; Vol. 11 Núm. 5; e22111528140Research, Society and Development; v. 11 n. 5; e221115281402525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/28140/24496Copyright (c) 2022 Romayla de Andrade Carvalho; Ana Viviam Souza Ferro Gomes; Rodolfo Adriano Rocha Ferraz; Francisca Ângela Sousa Castro; Estefany Monteiro Lopes Pereira; Gerson Luís Castro Ferreira ; Vitória Gindri Fortaleza; Maria Éryka Giovanna de Brito Fontenelehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCarvalho, Romayla de Andrade Gomes, Ana Viviam Souza FerroFerraz, Rodolfo Adriano Rocha Castro, Francisca Ângela Sousa Pereira, Estefany Monteiro LopesFerreira , Gerson Luís CastroFortaleza, Vitória Gindri Fontenele, Maria Éryka Giovanna de Brito2022-04-17T18:18:56Zoai:ojs.pkp.sfu.ca:article/28140Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:45:38.929354Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Use of L-PRF in the treatment of osteoradionecrosis
Uso de L-PRF en el tratamiento de la osteorradionecrosis
Uso do L-PRF no tratamento de osteorradionecrose
title Use of L-PRF in the treatment of osteoradionecrosis
spellingShingle Use of L-PRF in the treatment of osteoradionecrosis
Carvalho, Romayla de Andrade
L-PRF
Necrosis ósea
Bifosfonato.
L-PRF
Bone necrosis
Bisphosphonate.
L-PRF
Necrose óssea
Bifosfonato.
title_short Use of L-PRF in the treatment of osteoradionecrosis
title_full Use of L-PRF in the treatment of osteoradionecrosis
title_fullStr Use of L-PRF in the treatment of osteoradionecrosis
title_full_unstemmed Use of L-PRF in the treatment of osteoradionecrosis
title_sort Use of L-PRF in the treatment of osteoradionecrosis
author Carvalho, Romayla de Andrade
author_facet Carvalho, Romayla de Andrade
Gomes, Ana Viviam Souza Ferro
Ferraz, Rodolfo Adriano Rocha
Castro, Francisca Ângela Sousa
Pereira, Estefany Monteiro Lopes
Ferreira , Gerson Luís Castro
Fortaleza, Vitória Gindri
Fontenele, Maria Éryka Giovanna de Brito
author_role author
author2 Gomes, Ana Viviam Souza Ferro
Ferraz, Rodolfo Adriano Rocha
Castro, Francisca Ângela Sousa
Pereira, Estefany Monteiro Lopes
Ferreira , Gerson Luís Castro
Fortaleza, Vitória Gindri
Fontenele, Maria Éryka Giovanna de Brito
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carvalho, Romayla de Andrade
Gomes, Ana Viviam Souza Ferro
Ferraz, Rodolfo Adriano Rocha
Castro, Francisca Ângela Sousa
Pereira, Estefany Monteiro Lopes
Ferreira , Gerson Luís Castro
Fortaleza, Vitória Gindri
Fontenele, Maria Éryka Giovanna de Brito
dc.subject.por.fl_str_mv L-PRF
Necrosis ósea
Bifosfonato.
L-PRF
Bone necrosis
Bisphosphonate.
L-PRF
Necrose óssea
Bifosfonato.
topic L-PRF
Necrosis ósea
Bifosfonato.
L-PRF
Bone necrosis
Bisphosphonate.
L-PRF
Necrose óssea
Bifosfonato.
description Osteonecrosis is a pathology caused by necrosis of the gnathic bones of the maxilla and mandible. Either through antiresorptive drugs or radiotherapy. L-PRF is a platelet concentrate composed of leukocytes and growth factors capable of restoring vascularization and healing of soft and hard tissues. In addition to being the newest alternative treatment for osteonecrosis. In view of this, the work aims to evaluate the effectiveness of L-PRF in the prevention and treatment of osteonecrosis, and to clarify the mechanisms of this platelet concentrate in maxillary and mandibular osteonecrosis, in addition to other therapeutic approaches combined with L-PRF. Regarding the methodology, it is based on a literature review with a qualitative approach, which used the PUBMED, Google Scholar, Medline and IBECS databases. In the initial research, it resulted in 377 articles, after applying the filters that refer to articles published between 2017 and 2022, it generated a total of 21 articles chosen. According to the literature, L-PRF is effective in osteonecrosis, however, there are differences in the literature, as well as the fact that there is still no gold standard treatment. Therefore, L-PRF is effective, but it is not yet standardized, while each case of osteonecrosis has its peculiarity. However, when combined with other forms of treatments such as human bone morphogenetic protein (PMBs), the synergistic effect of these therapeutics accelerates the patient's healing process.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/28140
10.33448/rsd-v11i5.28140
url https://rsdjournal.org/index.php/rsd/article/view/28140
identifier_str_mv 10.33448/rsd-v11i5.28140
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/28140/24496
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 5; e22111528140
Research, Society and Development; Vol. 11 Núm. 5; e22111528140
Research, Society and Development; v. 11 n. 5; e22111528140
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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