Acute HIV infection with atypical clinical and laboratory presentation: case report

Detalhes bibliográficos
Autor(a) principal: Cyrino, Larissa Silva
Data de Publicação: 2021
Outros Autores: Figueiredo, Bárbara Queiroz de, Lopes Júnior, Célio Honório, Marques, Isadora Caixeta, Cyrino, Luana Silva, Silva, Maria Fernanda Carbonaro, Lessa, Maria Paula Pereira, Marra, Mauro Soares, Vale, Stéfani do, Pires, Bruno César de Oliveira
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/19016
Resumo: Introduction: Infection with the human immunodeficiency virus (HIV) represents, in Brazil and in the world, a public health problem: estimates show that, in 2017, 42,420 new cases of HIV were diagnosed in Brazil. Despite these high rates, it is noted that underdiagnosis is still a problem: data show that, in the United States, almost 15% of people infected with the HIV virus are unaware of this diagnosis. Objective: to report an atypical case of acute HIV infection, describing its clinical and laboratory evolution until the diagnosis was confirmed, in addition to highlighting the importance of clinical suspicion in cases where the clinical picture is uncommon and the initial serological tests are not definitive for diagnosis. Methodology: this is a clinical case study with a qualitative and descriptive perspective, which consists of a research that, in general, takes place with direct data collection, in which the researcher is the indispensable instrument. Case report: female patient, 20 years old, diagnosed with HIV. It did not manifest some of the most common main signs and symptoms, such as asthenia, pharyngitis and skin rashes, evidencing, on the other hand, phenomena related to severe liver involvement, with significant laboratory hepatitis, which is not common. Conclusion: early diagnosis and implementation of antiretroviral therapy (ART) collaborate with the achievement of favorable therapeutic results: it achieves a long viral suppression, preservation and even increase of immune functions and the conservation of a more homogeneous viral population.
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spelling Acute HIV infection with atypical clinical and laboratory presentation: case reportInfección aguda por VIH con presentación clínica y de laboratorio atípica: reporte de casoInfecção aguda pelo HIV com apresentação clínica e laboratorial atípicas: relato de casoVIHSerologíaEpidemiologíaDiagnóstico.HIVSerologyEpidemiologyDiagnosis.HIVSorologiaEpidemiologiaDiagnóstico.Introduction: Infection with the human immunodeficiency virus (HIV) represents, in Brazil and in the world, a public health problem: estimates show that, in 2017, 42,420 new cases of HIV were diagnosed in Brazil. Despite these high rates, it is noted that underdiagnosis is still a problem: data show that, in the United States, almost 15% of people infected with the HIV virus are unaware of this diagnosis. Objective: to report an atypical case of acute HIV infection, describing its clinical and laboratory evolution until the diagnosis was confirmed, in addition to highlighting the importance of clinical suspicion in cases where the clinical picture is uncommon and the initial serological tests are not definitive for diagnosis. Methodology: this is a clinical case study with a qualitative and descriptive perspective, which consists of a research that, in general, takes place with direct data collection, in which the researcher is the indispensable instrument. Case report: female patient, 20 years old, diagnosed with HIV. It did not manifest some of the most common main signs and symptoms, such as asthenia, pharyngitis and skin rashes, evidencing, on the other hand, phenomena related to severe liver involvement, with significant laboratory hepatitis, which is not common. Conclusion: early diagnosis and implementation of antiretroviral therapy (ART) collaborate with the achievement of favorable therapeutic results: it achieves a long viral suppression, preservation and even increase of immune functions and the conservation of a more homogeneous viral population.Introducción: La infección por el virus de la inmunodeficiencia humana (VIH) representa, en Brasil y en el mundo, un problema de salud pública: las estimaciones muestran que, en 2017, se diagnosticaron 42.420 nuevos casos de VIH en Brasil. A pesar de estas altas tasas, se observa que el infradiagnóstico sigue siendo un problema: los datos muestran que, en Estados Unidos, casi el 15% de las personas infectadas por el virus del VIH desconocen este diagnóstico. Objetivo: reportar un caso atípico de infección aguda por VIH, describiendo su evolución clínica y de laboratorio hasta la confirmación del diagnóstico, además de resaltar la importancia de la sospecha clínica en los casos en los que el cuadro clínico es poco común y las pruebas serológicas iniciales no son definitivas para el diagnóstico. . Metodología: se trata de un estudio de caso clínico con perspectiva cualitativa y descriptiva, que consiste en una investigación que, en general, se realiza con recolección directa de datos, en la que el investigador es el instrumento indispensable. Caso clínico: paciente de 20 años diagnosticada de VIH. No manifestó algunos de los principales signos y síntomas más comunes, como astenia, faringitis y erupciones cutáneas, evidenciándose, por otro lado, fenómenos relacionados con afectación hepática severa, con hepatitis de laboratorio importante, que no es común. Conclusión: el diagnóstico precoz y la implementación de la terapia antirretroviral (ART) colaboran con el logro de resultados terapéuticos favorables: logra una supresión viral prolongada, preservación e incluso aumento de las funciones inmunes y la conservación de una población viral más homogénea.Introdução: A infecção pelo vírus da imunodeficiência humana (HIV) representa, no Brasil e no mundo, um problema de saúde pública: as estimativas mostram que, em 2017, foram diagnosticados no Brasil 42.420 novos casos de HIV. Apesar dessas altas taxas, nota-se que o subdiagnóstico ainda é um problema: dados apontam que, nos Estados Unidos, quase 15% das pessoas infectadas pelo vírus HIV desconhecem esse diagnóstico. Objetivo: relatar um caso atípico de infecção aguda pelo HIV, descrevendo sua evolução clínica e laboratorial até que o diagnóstico fosse confirmado, além de evidenciar a importância da suspeição clínica nos casos em que o quadro clínico é incomum e os exames sorológicos iniciais não são definitivos para diagnóstico. Metodologia: trata-se de um estudo de caso clínico com perspectiva qualitativa e descritiva, que consiste em uma pesquisa em que, em geral, ocorre com coleta direta de dados, cujo o pesquisador é o instrumento indispensável. Relato de caso: paciente do sexo feminino, 20 anos, diagnosticada com HIV. Não manifestou alguns dos principais sinais e sintomas mais comuns, tais como astenia, faringite e erupções cutâneas evidenciando, por outro lado, fenômenos relacionados ao comprometimento acentuado do fígado, com hepatite laboratorial significativa, o que não é corriqueiro. Conclusão: o diagnóstico e a implementação da terapia anti retroviral (TAR) precoces colaboram com a obtenção de resultados terapêuticos favoráveis: consegue-se uma longa supressão viral, preservação e até mesmo aumento das funções imunitárias e a conservação de uma população viral mais homogênea.Research, Society and Development2021-08-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1901610.33448/rsd-v10i10.19016Research, Society and Development; Vol. 10 No. 10; e325101019016Research, Society and Development; Vol. 10 Núm. 10; e325101019016Research, Society and Development; v. 10 n. 10; e3251010190162525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/19016/16905Copyright (c) 2021 Larissa Silva Cyrino; Bárbara Queiroz de Figueiredo; Célio Honório Lopes Júnior; Isadora Caixeta Marques; Luana Silva Cyrino; Maria Fernanda Carbonaro Silva; Maria Paula Pereira Lessa; Mauro Soares Marra; Stéfani do Vale; Bruno César de Oliveira Pireshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCyrino, Larissa SilvaFigueiredo, Bárbara Queiroz deLopes Júnior, Célio Honório Marques, Isadora CaixetaCyrino, Luana SilvaSilva, Maria Fernanda CarbonaroLessa, Maria Paula PereiraMarra, Mauro SoaresVale, Stéfani do Pires, Bruno César de Oliveira2021-10-02T21:49:16Zoai:ojs.pkp.sfu.ca:article/19016Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:00.813559Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Acute HIV infection with atypical clinical and laboratory presentation: case report
Infección aguda por VIH con presentación clínica y de laboratorio atípica: reporte de caso
Infecção aguda pelo HIV com apresentação clínica e laboratorial atípicas: relato de caso
title Acute HIV infection with atypical clinical and laboratory presentation: case report
spellingShingle Acute HIV infection with atypical clinical and laboratory presentation: case report
Cyrino, Larissa Silva
VIH
Serología
Epidemiología
Diagnóstico.
HIV
Serology
Epidemiology
Diagnosis.
HIV
Sorologia
Epidemiologia
Diagnóstico.
title_short Acute HIV infection with atypical clinical and laboratory presentation: case report
title_full Acute HIV infection with atypical clinical and laboratory presentation: case report
title_fullStr Acute HIV infection with atypical clinical and laboratory presentation: case report
title_full_unstemmed Acute HIV infection with atypical clinical and laboratory presentation: case report
title_sort Acute HIV infection with atypical clinical and laboratory presentation: case report
author Cyrino, Larissa Silva
author_facet Cyrino, Larissa Silva
Figueiredo, Bárbara Queiroz de
Lopes Júnior, Célio Honório
Marques, Isadora Caixeta
Cyrino, Luana Silva
Silva, Maria Fernanda Carbonaro
Lessa, Maria Paula Pereira
Marra, Mauro Soares
Vale, Stéfani do
Pires, Bruno César de Oliveira
author_role author
author2 Figueiredo, Bárbara Queiroz de
Lopes Júnior, Célio Honório
Marques, Isadora Caixeta
Cyrino, Luana Silva
Silva, Maria Fernanda Carbonaro
Lessa, Maria Paula Pereira
Marra, Mauro Soares
Vale, Stéfani do
Pires, Bruno César de Oliveira
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cyrino, Larissa Silva
Figueiredo, Bárbara Queiroz de
Lopes Júnior, Célio Honório
Marques, Isadora Caixeta
Cyrino, Luana Silva
Silva, Maria Fernanda Carbonaro
Lessa, Maria Paula Pereira
Marra, Mauro Soares
Vale, Stéfani do
Pires, Bruno César de Oliveira
dc.subject.por.fl_str_mv VIH
Serología
Epidemiología
Diagnóstico.
HIV
Serology
Epidemiology
Diagnosis.
HIV
Sorologia
Epidemiologia
Diagnóstico.
topic VIH
Serología
Epidemiología
Diagnóstico.
HIV
Serology
Epidemiology
Diagnosis.
HIV
Sorologia
Epidemiologia
Diagnóstico.
description Introduction: Infection with the human immunodeficiency virus (HIV) represents, in Brazil and in the world, a public health problem: estimates show that, in 2017, 42,420 new cases of HIV were diagnosed in Brazil. Despite these high rates, it is noted that underdiagnosis is still a problem: data show that, in the United States, almost 15% of people infected with the HIV virus are unaware of this diagnosis. Objective: to report an atypical case of acute HIV infection, describing its clinical and laboratory evolution until the diagnosis was confirmed, in addition to highlighting the importance of clinical suspicion in cases where the clinical picture is uncommon and the initial serological tests are not definitive for diagnosis. Methodology: this is a clinical case study with a qualitative and descriptive perspective, which consists of a research that, in general, takes place with direct data collection, in which the researcher is the indispensable instrument. Case report: female patient, 20 years old, diagnosed with HIV. It did not manifest some of the most common main signs and symptoms, such as asthenia, pharyngitis and skin rashes, evidencing, on the other hand, phenomena related to severe liver involvement, with significant laboratory hepatitis, which is not common. Conclusion: early diagnosis and implementation of antiretroviral therapy (ART) collaborate with the achievement of favorable therapeutic results: it achieves a long viral suppression, preservation and even increase of immune functions and the conservation of a more homogeneous viral population.
publishDate 2021
dc.date.none.fl_str_mv 2021-08-13
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/19016
10.33448/rsd-v10i10.19016
url https://rsdjournal.org/index.php/rsd/article/view/19016
identifier_str_mv 10.33448/rsd-v10i10.19016
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/19016/16905
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 10; e325101019016
Research, Society and Development; Vol. 10 Núm. 10; e325101019016
Research, Society and Development; v. 10 n. 10; e325101019016
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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