Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/43991 |
Resumo: | The present study aims to identify the profile of antibacterial resistance in pharmacotherapy used in patients in an Intensive Care Unit (ICU) of a private hospital in Cascavel – PR. The objective is to identify the main resistant bacteria, the antibiotic therapy used and define the resistance profile of the identified microorganisms. This study is characterized as a retrospective cross-sectional observational study, based on exams carried out on patients admitted to an ICU of a private hospital in Cascavel – PR, from 2020 to 2021. The results were a higher prevalence of infection in male patient’s male (65.42%) and a higher rate of cases over 49 years of age. The biological sample used in both years analyzed was tracheal secretion with 61.82% in 2020 and 48.08% in 2021. and a total of 14 species of bacteria isolated. A prevalence of Klebsiella pneumoniae was observed with 36.64% of the total positive cultures in the period, followed by Pseudomonas aeruginosa (18.69%) and Staphylococcus aureus (11.21%). Regarding antibiotic resistance, K. pneumoniae presented an average of 62% to the drugs used in its treatment, accompanied by P. aeruginosa with an average of 57% resistance, and S. aureus presented 73.5%. The high prevalence of antibiotic resistance in the ICU of this institution suggests the need for improved surveillance and control of infections. This study offers data to improve clinical practice as well as the management of infections in the inpatient sector. |
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Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensivaPharmacotherapy and antimicrobial resistance in patients hospitalized in an intensive care unitFarmacoterapia y resistencia a los antimicrobianos en pacientes hospitalizados en una unidad de cuidados intensivosAntibacterianosUnidades de cuidados intensivosFarmacorresistencia bacteriana.AntibacterianosUnidades de terapia intensivaFarmacorresistência bacteriana.Anti-bacterial agentsIntensive care unitsDrug resistance, bacterial.The present study aims to identify the profile of antibacterial resistance in pharmacotherapy used in patients in an Intensive Care Unit (ICU) of a private hospital in Cascavel – PR. The objective is to identify the main resistant bacteria, the antibiotic therapy used and define the resistance profile of the identified microorganisms. This study is characterized as a retrospective cross-sectional observational study, based on exams carried out on patients admitted to an ICU of a private hospital in Cascavel – PR, from 2020 to 2021. The results were a higher prevalence of infection in male patient’s male (65.42%) and a higher rate of cases over 49 years of age. The biological sample used in both years analyzed was tracheal secretion with 61.82% in 2020 and 48.08% in 2021. and a total of 14 species of bacteria isolated. A prevalence of Klebsiella pneumoniae was observed with 36.64% of the total positive cultures in the period, followed by Pseudomonas aeruginosa (18.69%) and Staphylococcus aureus (11.21%). Regarding antibiotic resistance, K. pneumoniae presented an average of 62% to the drugs used in its treatment, accompanied by P. aeruginosa with an average of 57% resistance, and S. aureus presented 73.5%. The high prevalence of antibiotic resistance in the ICU of this institution suggests the need for improved surveillance and control of infections. This study offers data to improve clinical practice as well as the management of infections in the inpatient sector.El presente estudio tiene como objetivo identificar el perfil de resistencia antibacteriana en la farmacoterapia utilizada en pacientes de una Unidad de Cuidados Intensivos (UCI) de un hospital privado en Cascavel – PR. El objetivo es identificar las principales bacterias resistentes, la terapia antibiótica utilizada y definir el perfil de resistencia de los microorganismos identificados. Este estudio se caracteriza por ser un estudio observacional transversal retrospectivo, basado en exámenes realizados a pacientes ingresados en una UCI de un hospital privado de Cascavel – PR, de 2020 a 2021. Los resultados fueron una mayor prevalencia de infección en pacientes masculinos. (65,42%) y una mayor tasa de casos mayores de 49 años. La muestra biológica utilizada en los dos años analizados fue secreción traqueal con un 61,82% en 2020 y un 48,08% en 2021. y un total de 14 especies de bacterias aisladas. Se observó prevalencia de Klebsiella pneumoniae con 36,64% del total de cultivos positivos en el período, seguida de Pseudomonas aeruginosa (18,69%) y Staphylococcus aureus (11,21%). En cuanto a la resistencia a los antibióticos, K. pneumoniae presentó un promedio de 62% a los fármacos utilizados en su tratamiento, acompañado de P. aeruginosa con un promedio de 57% de resistencia, y S. aureus presentó 73,5%. La alta prevalencia de resistencia a los antibióticos en la UCI de esta institución sugiere la necesidad de mejorar la vigilancia y control de las infecciones, este estudio ofrece datos para mejorar la práctica clínica, así como el manejo de las infecciones en el sector hospitalario.O presente estudo visa identificar o perfil de resistência antibacteriana na farmacoterapia utilizada em pacientes de uma Unidade de Terapia Intensiva (UTI), de um hospital particular de Cascavel – PR. Como objetivo, tem-se a identificação das principais bactérias resistentes, a antibioticoterapia utilizada e definição do perfil de resistência, dos microrganismos identificados. Este estudo se caracteriza como observacional transversal retrospectivo, elaborado a partir de exames realizados em pacientes internados em uma UTI de um hospital particular de Cascavel – PR, no período de 2020 a 2021. Teve como resultados, uma maior prevalência de infecção em pacientes do sexo masculino (65,42%) e um maior índice de casos a partir de 49 anos de idade. A amostra biológica utilizada, em ambos os anos analisados foi de secreção traqueal com 61,82% em 2020 e 48,08% em 2021.e um total de 14 espécies de bactérias isoladas. Observou-se uma prevalência da Klebsiella pneumoniae com 36,64% do total de culturas positivas no período, seguida por Pseudomonas aeruginosa (18,69%) e Staphylococcus aureus (11,21%). Em relação à resistência aos antibióticos, a K. pneumoniae apresentou uma média de 62% aos medicamentos utilizados no seu tratamento, acompanhada por P. aeruginosa com 57% de média de resistência, e S. aureus apresentou 73,5%. A grande prevalência de resistência aos antibióticos na UTI desta instituição, sugere a necessidade de melhoria na vigilância e controle das infecções, este estudo oferece dados para melhoria da prática clínica bem como da gestão de infecções no setor de internamento.Research, Society and Development2023-11-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4399110.33448/rsd-v12i12.43991Research, Society and Development; Vol. 12 No. 12; e71121243991Research, Society and Development; Vol. 12 Núm. 12; e71121243991Research, Society and Development; v. 12 n. 12; e711212439912525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/43991/35303Copyright (c) 2023 Neoraldo Junior Antunes; Anthony Gabriel Pusini de Souza; Claudinei Mesquita da Silva; Leyde Daiane de Pederhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAntunes, Neoraldo JuniorSouza, Anthony Gabriel Pusini de Silva, Claudinei Mesquita da Peder, Leyde Daiane de 2023-11-24T09:58:06Zoai:ojs.pkp.sfu.ca:article/43991Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-11-24T09:58:06Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva Pharmacotherapy and antimicrobial resistance in patients hospitalized in an intensive care unit Farmacoterapia y resistencia a los antimicrobianos en pacientes hospitalizados en una unidad de cuidados intensivos |
title |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva |
spellingShingle |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva Antunes, Neoraldo Junior Antibacterianos Unidades de cuidados intensivos Farmacorresistencia bacteriana. Antibacterianos Unidades de terapia intensiva Farmacorresistência bacteriana. Anti-bacterial agents Intensive care units Drug resistance, bacterial. |
title_short |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva |
title_full |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva |
title_fullStr |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva |
title_full_unstemmed |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva |
title_sort |
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva |
author |
Antunes, Neoraldo Junior |
author_facet |
Antunes, Neoraldo Junior Souza, Anthony Gabriel Pusini de Silva, Claudinei Mesquita da Peder, Leyde Daiane de |
author_role |
author |
author2 |
Souza, Anthony Gabriel Pusini de Silva, Claudinei Mesquita da Peder, Leyde Daiane de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Antunes, Neoraldo Junior Souza, Anthony Gabriel Pusini de Silva, Claudinei Mesquita da Peder, Leyde Daiane de |
dc.subject.por.fl_str_mv |
Antibacterianos Unidades de cuidados intensivos Farmacorresistencia bacteriana. Antibacterianos Unidades de terapia intensiva Farmacorresistência bacteriana. Anti-bacterial agents Intensive care units Drug resistance, bacterial. |
topic |
Antibacterianos Unidades de cuidados intensivos Farmacorresistencia bacteriana. Antibacterianos Unidades de terapia intensiva Farmacorresistência bacteriana. Anti-bacterial agents Intensive care units Drug resistance, bacterial. |
description |
The present study aims to identify the profile of antibacterial resistance in pharmacotherapy used in patients in an Intensive Care Unit (ICU) of a private hospital in Cascavel – PR. The objective is to identify the main resistant bacteria, the antibiotic therapy used and define the resistance profile of the identified microorganisms. This study is characterized as a retrospective cross-sectional observational study, based on exams carried out on patients admitted to an ICU of a private hospital in Cascavel – PR, from 2020 to 2021. The results were a higher prevalence of infection in male patient’s male (65.42%) and a higher rate of cases over 49 years of age. The biological sample used in both years analyzed was tracheal secretion with 61.82% in 2020 and 48.08% in 2021. and a total of 14 species of bacteria isolated. A prevalence of Klebsiella pneumoniae was observed with 36.64% of the total positive cultures in the period, followed by Pseudomonas aeruginosa (18.69%) and Staphylococcus aureus (11.21%). Regarding antibiotic resistance, K. pneumoniae presented an average of 62% to the drugs used in its treatment, accompanied by P. aeruginosa with an average of 57% resistance, and S. aureus presented 73.5%. The high prevalence of antibiotic resistance in the ICU of this institution suggests the need for improved surveillance and control of infections. This study offers data to improve clinical practice as well as the management of infections in the inpatient sector. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-11-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/43991 10.33448/rsd-v12i12.43991 |
url |
https://rsdjournal.org/index.php/rsd/article/view/43991 |
identifier_str_mv |
10.33448/rsd-v12i12.43991 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/43991/35303 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 12 No. 12; e71121243991 Research, Society and Development; Vol. 12 Núm. 12; e71121243991 Research, Society and Development; v. 12 n. 12; e71121243991 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052633808109568 |