Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/31515 |
Resumo: | Several neurodegenerative diseases current therapies, such as for Parkinson’s disease, Alzheimer’s disease and Multiple Sclerosis, need constant improvement, aiming to enhance quality of life, symptomatic improvement, and possibly recovery. Thus, this integrative literature review aims to understand how Cannabidiol (CBD) can be used in the treatment of neurodegenerative diseases, analyzing applicability, therapeutic effects and the method in which this substance is used as this medicinal form. From a search in PubMed, VHL and LILACS databases, articles in English were selected, published between the years 2016 and 2021, which addressed the subject and delved into the effects of CBD on neurodegenerative diseases, specifically: Parkinson's Disease, Multiple Sclerosis, Tuberous Sclerosis, Alzheimer's Disease and Huntington's Disease. After performing the integrative analysis, it was concluded that CBD is a neuroprotective and anti-inflammatory agent, acting to improve motor performance, decrease pain and spasticity. Therefore, it is possible to conclude that, although more studies are needed about its effects and therapeutic mechanisms, cannabidiol is a viable and beneficial substance for use in new therapies for neurodegenerative diseases. |
| id |
UNIFEI_2f5e6514623c1ee33caa239d0badfeec |
|---|---|
| oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/31515 |
| network_acronym_str |
UNIFEI |
| network_name_str |
Research, Society and Development |
| repository_id_str |
|
| spelling |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptomsEnfoque terapêutico del canabidiol en enfermidades neurodegenerativas: evaluación de los efectos sobre la progresión de estas enfermedades y sus sintomasAbordagem terapêutica do Canabidiol sobre as Doenças Neurodegenerativas: avaliação dos efeitos na progressão dessas doenças e seus sintomasCannabidiolSeñalizaciónn de cannabidiolEnfermedades neurodegenerativasTratamiento.CanabidiolSinalização de CanabidiolDoenças neurodegenerativasTratamento.CannabidiolCannabidiol signalingNeurodegenerative diseasesTreatment.Several neurodegenerative diseases current therapies, such as for Parkinson’s disease, Alzheimer’s disease and Multiple Sclerosis, need constant improvement, aiming to enhance quality of life, symptomatic improvement, and possibly recovery. Thus, this integrative literature review aims to understand how Cannabidiol (CBD) can be used in the treatment of neurodegenerative diseases, analyzing applicability, therapeutic effects and the method in which this substance is used as this medicinal form. From a search in PubMed, VHL and LILACS databases, articles in English were selected, published between the years 2016 and 2021, which addressed the subject and delved into the effects of CBD on neurodegenerative diseases, specifically: Parkinson's Disease, Multiple Sclerosis, Tuberous Sclerosis, Alzheimer's Disease and Huntington's Disease. After performing the integrative analysis, it was concluded that CBD is a neuroprotective and anti-inflammatory agent, acting to improve motor performance, decrease pain and spasticity. Therefore, it is possible to conclude that, although more studies are needed about its effects and therapeutic mechanisms, cannabidiol is a viable and beneficial substance for use in new therapies for neurodegenerative diseases.Las terapias actuales para varias enfermedades neurodegenerativas, como la enfermedad de Parkinson, la enfermedad de Alzheimer y la esclerosis múltiple, necesitan una mejora constante, con el objetivo de lograr un progreso en la calidad de vida, una mejoría sintomática y posiblemente una recuperación. Así, esta revisión integrativa de la literatura tiene como objetivo comprender cómo se puede utilizar el Cannabidiol (CBD) en el tratamiento de enfermedades neurodegenerativas, analizando su aplicabilidad, sus efectos terapéuticos y el método en el que se utiliza esta sustancia en su forma medicinal. A partir de una búsqueda en las bases de datos PubMed, BVS y LILACS, se seleccionaron artículos en inglés, publicados entre los años 2016 y 2021, que abordaran el tema y profundizaran en los efectos del CBD de enfermedades neurodegenerativas de manera que a las siguientes enfermedades específicamente: Parkinson Enfermedad, Esclerosis Múltiple, Esclerosis Tuberosa, Enfermedad de Alzheimer y Enfermedad de Huntington. Luego de realizar el análisis integrativo, se concluyó que el CBD es un agente neuroprotector y antiinflamatorio, actuando para mejorar el desempeño motor, disminuir el dolor y la espasticidad. Por tanto, es posible concluir que, aunque se necesitan más estudios sobre sus efectos y mecanismos terapéuticos, el cannabidiol es una sustancia viable y beneficiosa para su uso en nuevas terapias para enfermedades neurodegenerativas.As atuais terapias de diversas doenças neurodegenerativas, como doença de Parkinson, doença de Alzheimer e Esclerose múltipla, necessitam de constante aprimoramento, visando trazer progresso na qualidade de vida, melhora sintomatológica, e possivelmente recuperação. Desta forma, essa revisão de literatura integrativa visa entender como o Canabidiol (CBD) pode ser utilizado no tratamento de doenças neurodegenerativas, analisando a sua aplicabilidade, seus efeitos terapêuticos e o método no qual essa substância é usada em sua forma medicinal. A partir de uma busca nas bases de dados PubMed, BVS e LILACS, foram selecionados artigos em língua inglesa, publicados entre os anos de 2016 e 2021, os quais abordaram o assunto e aprofundaram-se nos efeitos do CBD desde as doenças neurodegenerativas de forma geral até as seguintes doenças de forma específica: Doença de Parkinson, Esclerose Múltipla, Esclerose Tuberosa, Doença de Alzheimer e Doença de Huntington. Realizada a análise integrativa, chegou-se à conclusão de que o CBD é um agente neuroprotetor e anti-inflamatório, atuando na melhora do desempenho motor, na diminuição da dor e na espasticidade. Portanto, é possível concluir que, apesar de serem necessários mais estudos acerca dos seus efeitos e mecanismos terapêuticos, o canabidiol é uma substância viável e benéfica na utilização em novas terapias de doenças neurodegenerativas.Research, Society and Development2022-06-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3151510.33448/rsd-v11i8.31515Research, Society and Development; Vol. 11 No. 8; e56411831515Research, Society and Development; Vol. 11 Núm. 8; e56411831515Research, Society and Development; v. 11 n. 8; e564118315152525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/31515/26803Copyright (c) 2022 Ana Luiza Magalhães Silva; Ana Gabriela Hannum Noleto; Ana Laura Barra Borges; Bárbara da Costa Santana Borges; Giovanna Borges Magalhães; Luana Alves Simões; Rodrigo Scaliante de Mourahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Ana Luiza Magalhães Noleto, Ana Gabriela Hannum Borges, Ana Laura Barra Borges, Bárbara da Costa Santana Magalhães, Giovanna Borges Simões, Luana Alves Moura, Rodrigo Scaliante de 2022-07-01T13:34:06Zoai:ojs.pkp.sfu.ca:article/31515Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:47:49.829448Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms Enfoque terapêutico del canabidiol en enfermidades neurodegenerativas: evaluación de los efectos sobre la progresión de estas enfermedades y sus sintomas Abordagem terapêutica do Canabidiol sobre as Doenças Neurodegenerativas: avaliação dos efeitos na progressão dessas doenças e seus sintomas |
| title |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms |
| spellingShingle |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms Silva, Ana Luiza Magalhães Cannabidiol Señalizaciónn de cannabidiol Enfermedades neurodegenerativas Tratamiento. Canabidiol Sinalização de Canabidiol Doenças neurodegenerativas Tratamento. Cannabidiol Cannabidiol signaling Neurodegenerative diseases Treatment. |
| title_short |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms |
| title_full |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms |
| title_fullStr |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms |
| title_full_unstemmed |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms |
| title_sort |
Therapeutic approach of cannabidiol on neurodegenerative diseases: evaluation of the effects on the progression of these diseases and their symptoms |
| author |
Silva, Ana Luiza Magalhães |
| author_facet |
Silva, Ana Luiza Magalhães Noleto, Ana Gabriela Hannum Borges, Ana Laura Barra Borges, Bárbara da Costa Santana Magalhães, Giovanna Borges Simões, Luana Alves Moura, Rodrigo Scaliante de |
| author_role |
author |
| author2 |
Noleto, Ana Gabriela Hannum Borges, Ana Laura Barra Borges, Bárbara da Costa Santana Magalhães, Giovanna Borges Simões, Luana Alves Moura, Rodrigo Scaliante de |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Ana Luiza Magalhães Noleto, Ana Gabriela Hannum Borges, Ana Laura Barra Borges, Bárbara da Costa Santana Magalhães, Giovanna Borges Simões, Luana Alves Moura, Rodrigo Scaliante de |
| dc.subject.por.fl_str_mv |
Cannabidiol Señalizaciónn de cannabidiol Enfermedades neurodegenerativas Tratamiento. Canabidiol Sinalização de Canabidiol Doenças neurodegenerativas Tratamento. Cannabidiol Cannabidiol signaling Neurodegenerative diseases Treatment. |
| topic |
Cannabidiol Señalizaciónn de cannabidiol Enfermedades neurodegenerativas Tratamiento. Canabidiol Sinalização de Canabidiol Doenças neurodegenerativas Tratamento. Cannabidiol Cannabidiol signaling Neurodegenerative diseases Treatment. |
| description |
Several neurodegenerative diseases current therapies, such as for Parkinson’s disease, Alzheimer’s disease and Multiple Sclerosis, need constant improvement, aiming to enhance quality of life, symptomatic improvement, and possibly recovery. Thus, this integrative literature review aims to understand how Cannabidiol (CBD) can be used in the treatment of neurodegenerative diseases, analyzing applicability, therapeutic effects and the method in which this substance is used as this medicinal form. From a search in PubMed, VHL and LILACS databases, articles in English were selected, published between the years 2016 and 2021, which addressed the subject and delved into the effects of CBD on neurodegenerative diseases, specifically: Parkinson's Disease, Multiple Sclerosis, Tuberous Sclerosis, Alzheimer's Disease and Huntington's Disease. After performing the integrative analysis, it was concluded that CBD is a neuroprotective and anti-inflammatory agent, acting to improve motor performance, decrease pain and spasticity. Therefore, it is possible to conclude that, although more studies are needed about its effects and therapeutic mechanisms, cannabidiol is a viable and beneficial substance for use in new therapies for neurodegenerative diseases. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-06-29 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/31515 10.33448/rsd-v11i8.31515 |
| url |
https://rsdjournal.org/index.php/rsd/article/view/31515 |
| identifier_str_mv |
10.33448/rsd-v11i8.31515 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/31515/26803 |
| dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Research, Society and Development |
| publisher.none.fl_str_mv |
Research, Society and Development |
| dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 8; e56411831515 Research, Society and Development; Vol. 11 Núm. 8; e56411831515 Research, Society and Development; v. 11 n. 8; e56411831515 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
| instname_str |
Universidade Federal de Itajubá (UNIFEI) |
| instacron_str |
UNIFEI |
| institution |
UNIFEI |
| reponame_str |
Research, Society and Development |
| collection |
Research, Society and Development |
| repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
| repository.mail.fl_str_mv |
rsd.articles@gmail.com |
| _version_ |
1797052768451559424 |